Patents by Inventor Lars KADERALI

Lars KADERALI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostics and therapy for human respiratory syncytial virus
    Patent number: 11952631
    Abstract: The present invention pertains to a method for the identification of genetic variants that are associated with the severity of an infectious disease. The invention further pertains to a set of genetic factors associated with the severity of Human respiratory syncytial virus (HRSV) infection, for example in human infants. The genetic polymorphisms identified according to the present invention are for use in the diagnostic of infectious diseases and patient stratification in order to avoid or reduce the occurrence of fatal events during infection or to elect the most appropriate therapeutic approach to treat the disease.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: April 9, 2024
    Assignees: MEDIZINISCHE HOCHSCHULE HANNOVER, TWINCORE ZENTRUM FÜR EXPERIMENTELLE UND KLINISCHE INFEKTIONSFORSCHUNG GMBH, TECHNISCHE UNIVERSITÄT DRESDEN
    Inventors: Daniel Todt, Sibylle Haid, Martin Wetzke, Gesine Hansen, Chris Lauber, Lars Kaderali, Thomas Pietschmann
  • DIAGNOSTICS AND THERAPY FOR HUMAN RESPIRATORY SYNCYTIAL VIRUS
    Publication number: 20200283848
    Abstract: The present invention pertains to a method for the identification of genetic variants that are associated with the severity of an infectious disease. The invention further pertains to a set of genetic factors associated with the severity of Human respiratory syncytial virus (HRSV) infection, for example in human infants. The genetic polymorphisms identified according to the present invention are for use in the diagnostic of infectious diseases and patient stratification in order to avoid or reduce the occurrence of fatal events during infection or to elect the most appropriate therapeutic approach to treat the disease.
    Type: Application
    Filed: October 9, 2018
    Publication date: September 10, 2020
    Applicants: MEDIZINISCHE HOCHSCHULE HANNOVER, TWINCORE ZENTRUM FÜR EXPERIMENTELLE UND KLINISCHE INFEKTIONSFORSCHUNG GMBH, TECHNISCHE UNIVERSITÄT DRESDEN
    Inventors: Daniel TODT, Sibylle HAID, Martin WETZKE, Gesine HANSEN, Chris LAUBER, Lars KADERALI, Thomas PIETSCHMANN
  • AGE DETERMINATION OF HUMAN INDIVIDUAL
    Publication number: 20200115754
    Abstract: The present invention relates to a method for determining the biological age of human skin comprising providing human skin cells, determining a methylation level of at least two CpG-dinucleotides of a specific region of at least one chromosome of said skin cells and determining the biological age of said skin cells by comparing said determined methylation level with empirically determined data representing a correlation between the methylation level of the CpG-nucleotide and the chronological age of at least one human individual.
    Type: Application
    Filed: June 12, 2018
    Publication date: April 16, 2020
    Inventors: Marc WINNEFELD, Elisabeth WURZER, Boris KRISTOF, Lars KADERALI