Patents by Inventor Lars Kongsbak Poulsen

Lars Kongsbak Poulsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescent proteins
    Patent number: 7314915
    Abstract: The present invention relates to novel variants of the fluorescent protein GFP having improved fluorescence properties.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: January 1, 2008
    Assignee: Fisher BioImage APS
    Inventors: Ole Thastrup, Søren Tullin, Lars Kongsbak Poulsen, Sara Petersen Bjørn
  • Fluorescent proteins
    Patent number: 6818443
    Abstract: The present invention relates to novel variants of the fluorescent protein GFP having improved fluorescence properties.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: November 16, 2004
    Assignee: BioImage A/S
    Inventors: Ole Thastrup, Søren Tullin, Lars Kongsbak Poulsen, Sara Petersen Bjørn
  • Method of detecting biologically active substances
    Patent number: 6566083
    Abstract: The present invention relates to a method of detecting biologically active substances affecting intracellular processes, an isolated DNA, a vector and a cell for use in the method. More specifically, the present invention provides a method for detecting a biologically active substance that affects intracellular processes mediated through a protein kinase or a second messenger, which comprises incubating a cell with a test substance and measuring any change caused by the test substance in the flourescence of (i) a wild-type or modified green flourescent protein (GFP) having a protein kinase recognition site, (ii) a modified GFP containing a second messenger binding domain, or (iii) a hybrid polypeptide having a wild-type or modified GFP and an attached protein kinase recognition site or a second messenger binding domain.
    Type: Grant
    Filed: July 2, 1999
    Date of Patent: May 20, 2003
    Assignee: Novo Nordisk A/S
    Inventors: Ole Thastrup, Søren Tullin, Lars Kongsbak Poulsen, Sara Petersen Bjørn
  • Novel fluorescent proteins
    Publication number: 20020107362
    Abstract: The present invention relates to novel variants of the fluorescent protein GFP having improved fluorescence properties.
    Type: Application
    Filed: June 1, 2001
    Publication date: August 8, 2002
    Applicant: BIOIMAGE A/S
    Inventors: Ole Thastrup, Soren Tullin, Lars Kongsbak Poulsen, Sara Petersen Bjorn
  • Fluorescent proteins
    Patent number: 6172188
    Abstract: The present invention relates to novel variants of the fluorescent protein GFP having improved fluorescence properties.
    Type: Grant
    Filed: March 17, 1997
    Date of Patent: January 9, 2001
    Inventors: Ole Thastrup, Søren Tullin, Lars Kongsbak Poulsen, Sara Petersen Bjørn
  • Method of detecting biologically active substances by using green fluorescent protein
    Patent number: 5958713
    Abstract: The present invention provides a method for detecting a biologically active substance that affects intracellular processes mediated through a protein kinase or second messenger, which comprises incubating a cell with a test substance and measuring any change caused by the test substance in the fluorescence of (i) green fluorescent protein (GFP) having a protein kinase recognition site or (ii) GFP that has been modified to contain a second messenger binding domain.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: September 28, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Ole Thastrup, S.o slashed.ren Tullin, Lars Kongsbak Poulsen, Sara Petersen Bj.o slashed.rn