Abstract: The present invention relates to a device for providing spongy bone with bone substitute and/or bone reinforcing material, wherein at least one perforating device (4) is provided for making at least one hole (5) in the spongy bone (1) and wherein at least one flushing or rinsing device (6) is provided for flushing or rinsing the hole (5) with a rinsing agent (7). At least one vacuum source (9) is provided for generating a vacuum in the hole (5) in the spongy bone (1) for sucking and/or facilitating insertion or feeding of the bone substitute and/or bone reinforcing material (3) into said spongy bone (1). The invention also relates to bone substitute and/or bone reinforcing material and methods in connection with the invention.

Abstract: The present invention relates to a method for manufacturing a membrane or wall (3) of a material, which is capable of vapour/vacuum deposition, over an opening of an object (2). The method includes: placing the opening with a defined rim against a backing surface (4) coated with a layer (5) repellent to the depositable material; depositing of the depositable material on the object (2) and the backing surface (4) to form an element; separation of the element from the hacking surface (4) leaving a membrane (3) integral with the element. The invention also relates to such an object provided with a membrane (3), and particularly an ultrasonic transducer (11) provided with a front membrane (3).

Abstract: A medical composition is disclosed, which is injectable and which comprises a mixture of native components, which are obtainable by culturing one or more cell samples from a human or animal during normal conditions, said native components being included in the group consisting of growth factors, extracellular matrix proteins, and other substances produced by said cell samples during normal conditions, and a pharmaceutically acceptable carrier, as well as a method for producing the native components, a method for producing the medical composition, a method for treating a subject in need of tissue repair by injection of the medical composition, and use of said mixture of native components for the production of said medical composition for tissue repair via injection.

Abstract: The present invention relates to a device for producing a hardenable mass, preferably bone substitute and/or bone reinforcing material or bone cement or similar material. A mixing container (3) has a mixing space (4) in which at least one powder and at least one liquid component (5, 6) are mixed to provide the hardenable mass (2). A piston means (7) is provided in the mixing space (4) of the mixing container (3). At least one means (8) which is rotatable relative to the mixing container (3) cooperates with the piston means (7) for, in a retaining position (P1), retaining said piston means (7) relative to the mixing container (3) and, by rotation to a release position (P2), releasing the piston means (7) such that said piston means can move in a direction (U) towards at least one opening (49) through which said mass (2) can pass out of the mixing space (4).

Abstract: The invention refers to an injectable composition for a bone mineral substitute material, which comprises a dry powder mixed with an aqueous liquid. The powder comprises a first reaction component comprising a calcium sulphate hemihydrate with the capability of being hardened to calcium sulphate dihydrate when reacting with said aqueous liquid; a second reaction component, which comprises a calcium phosphate with the capability of being hardened to a calcium phosphate cement when reacting with said aqueous liquid; and at least one accelerator for the reaction of said first and/or second reaction component with said aqueous liquid. A method of producing an injectable bone mineral substitute material is also provided, wherein the composition is mixed in a closed mixing and delivery system for delivery.

Abstract: An emergency warning service is described for providing emergency related information to users of communication terminals in a mobile communication system. The service comprises a procedure of establishing a service agreement in relation with a user. The service agreement comprises at least an identification of a user and a time period during which period the user is allowed access to emergency warnings. After receiving an emergency warning message from an emergency warning message provider, the message comprising information at least regarding a type of emergency and an emergency location, it is decided whether or not the user is to receive the warning message. The decision is based at least on said service agreement. Then, depending on the decision, at least said warning message is transmitted to the user.

Abstract: The invention refers to an injectable composition for a bone mineral substitute material, which comprises a dry powder mixed with an aqueous liquid. The powder comprises a first reaction component comprising a calcium suphate hemihydrate with the capability of being hardened to calcium sulphate dihydrate when reacting with said aqueous liquid; a second reaction component, which comprises a calcium phosphate with the capability of being hardened to a calcium phosphate cement when reacting with said aqueous liquid; and at least one accelerator for the reaction of said first and/or second reaction component with said aqueous liquid. A method of producing an injectable bone mineral substitute material is also provided, wherein the composition is mixed in a closed mixing and delivery system for delivery.

Abstract: The invention refers to an injectable composition for a bone mineral substitute material, which comprises a dry powder mixed with an aqueous liquid. The powder comprises a first reaction component comprising a calcium sulphate hemihydrate with the capability of being hardened to calcium sulphate dihydrate when reacting with said aqueous liquid; a second reaction component, which comprises a calcium phosphate with the capability of being hardened to a calcium phosphate cement when reacting with said aqueous liquid; and at least one accelerator for the reaction of said first and/or second reaction component with said aqueous liquid. A method of producing an injectable bone mineral substitute material is also provided, wherein the composition is mixed in a closed mixing and delivery system for delivery.

Abstract: The invention refers to an injectable composition for a bone mineral substitute material, which comprises a dry powder mixed with an aqueous liquid. The powder comprises a first reaction component comprising a calcium sulphate hemihydrate with the capability of being hardened to calcium sulphate dihydrate when reacting with said aqueous liquid; a second reaction component, which comprise a calcium phosphate with the capability of being hardened to a calcium phosphate cement when reacting with said aqueous liquid; and at least one accelerator for the reaction of said first and/or second reaction component with said aqueous liquid. A method of producing an injectable bone mineral substitute material is also provided, wherein the composition is mixed in a closed mixing and delivery system for delivery.

Abstract: The present invention relates to a device for producing a hardenable mass, preferably bone substitute and/or bone reinforcing material or bone cement or similar material. A mixing container (3) has a mixing space (4) in which at least one powder and at least one liquid component (5, 6) are mixed to provide the hardenable mass (2). A piston means (7) is provided in the mixing space (4) of the mixing container (3). At least one means (8) which is rotatable relative to the mixing container (3) cooperates with the piston means (7) for, in a retaining position (P1), retaining said piston means (7) relative to the mixing container (3) and, by rotation to a release position (P2), releasing the piston means (7) such that said piston means can move in a direction (U) towards at least one opening (49) through which said mass (2) can pass out of the mixing space (4).

Abstract: The present invention relates to a device for providing spongy bone with bone substitute and/or bone reinforcing material, wherein at least one perforating device (4) is provided for making at least one hole (5) in the spongy bone (1) and wherein at least one flushing or rinsing device (6) is provided for flushing or rinsing the hole (5) with a rinsing agent (7). At least one vacuum source (9) is provided for generating a vacuum in the hole (5) in the spongy bone (1) for sucking and/or facilitating insertion or feeding of the bone substitute and/or bone reinforcing material (3) into said spongy bone (1). The invention also relates to bone substitute and/or bone reinforcing material and methods in connection with the invention.

Abstract: An injectable bone mineral substitute material composition with the capability of being hardened in a body fluid in vivo, which comprises at least one calcium phosphate component and at least one calcium sulfate component as a dry mixture mixed with an aqueous liquid, and at least one accelerator, the at least one calcium sulfate component being particulate hardened calcium sulfate, which has a specified particle size that is in order to confer injectability to the composition. The invention also concerns the bone mineral substitute material produced from the composition as well as methods and uses thereof.

Abstract: The invention relates to an ultrasound probe having a central opening (22) in an arrangement for ultrasound treatment of a patient. The probe has a front portion adapted to be placed at, against or in an object to be treated and is arranged to emit an ultrasound field having an intensity maximum located in the object for heating thereof. The central opening (22) improves the emitted intensity pattern and enables irrigation of the transmitter.

Abstract: The invention refers to an artificial bone mineral substitute material which comprises at least one ceramic and at least one water soluble non-ionic X-ray contrast agent. The invention refers to a composition for producing the same, which further comprises an aqueous liquid, as well as the use of the composition as a X-ray contrast medium.

Abstract: The present invention relates to a device for mini-invasive ultrasound treatment of an object. At least one therapeutic ultrasound transducer (2) is arranged for treatment of the object (5) by generating an ultrasonic field (3), the temperature focus (F) of which is located in the object (5) for heating thereof. The therapeutic ultrasound transducer (2) comprises a probe (10) adapted to be inserted into the body in the direction towards the object (5) and comprises a front portion (10a) adapted to be located at, against or in the object (5). Said probe (10) comprises at least one transmitter element (11) for generating said ultrasonic field (3). The transmitter element (11) for generating the ultrasonic field (3) is arranged behind the front portion (10a) such that the transmitter element (11) does not heat or substantially not heat the front portion (10a) when in operation.

Abstract: The present invention relates to a device for non-invasive ultrasound treatment of an object (5) of a patient, wherein at least two therapeutic ultrasound transducers (2a, 2b) are arranged for treatment of the object (5) by generating at least one ultrasonic field (3), the temperature focus (F) of which can be located in the object (5). A diagnostic ultrasound transducer (8) is arranged to determine the acoustic properties of the patient's (4) tissue (10) between the area on which the therapeutic ultrasound transducers (2a, 2b) are to be located during treatment and the object (5) in order to, in dependence of the acoustic properties determined by the diagnostic ultrasound transducer (8), set the therapeutic ultrasound transducers (2a, 2b) relative to the object (5).

Abstract: The invention refers to an injectable composition for a bone mineral substitute material, which comprises a dry powder mixed with an aqueous liquid. The powder comprsises a first reaction component comprising a calcium sulphate hemihydrate with the capability of being hardened to calcium sulphate dihydrate when reacting with said aqueous liquid; a second reaction component, which comprise a calcium phosphate with the capability of being hardened to a calcium phosphate cement when reacting with said aqueous liquid; and at least one accelerator for the reaction of said fist and/or second reaction component with said aqueous liquid. A method of producing an injectable bone mineral substitute material is also provided, wherein the composition is mixed in a closed mixing an d delivery system for delivery.

Abstract: An injectable bone mineral substitute material composition comprises an inorganic bone cement powder and a biologically compatible oil. The oil is an intermixture with the cement powder at a concentration of less than 10 wt % of the total weight of the composition in order to improve the rheology of the same. In a method of intermixing a powder of an implant material and a biologically compatible oil to a composition the oil is mixed with the powder of implant material at an elevated temperature.

Abstract: The invention relates to a method for the preparation in a reactor of a UHMWPE material doped with an antioxidant, preferably vitamin E.

Abstract: The present invention relates to a device for non-invasive treatment of biological tissue, whereby the treatment aim at changing or degenerating said tissue. This device has a treatment transducer (2) comprising at least one ultrasonic transducer (3 and/or 4) which is provided to treat intervertebral discs (1), preferably nucleus pulposus (1a), by means of ultrasound, whereby the ultrasonic field of the ultrasonic transducer (3 and/or 4) is focused in said intervertebral disc (1), preferably in nucleus pulposus (1a), for heating the tissue therein, to such temperatures that the tissue in the focal area (5) degenerates, whereby the pressure in the intervertebral disc (1) and thus, the pressure against the spinal cord (6) is reduced.