Patents by Inventor LARS LINDEROTH

LARS LINDEROTH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110166321
    Abstract: The invention relates to a derivative of a GLP-1 analogue, which analogue comprises a first K residue at a position corresponding to position 37 of GLP-1(7-37) (SEQ ID NO: 1), a second K residue at a position corresponding to position 26 of GLP-1(7-37), and a maximum of ten amino acid modifications as compared to GLP-1(7-37), wherein the first K residue is designated K37, and the second K residue is designated K26, which derivative comprises two albumin binding moieties attached to K26 and K37, respectively, wherein the albumin binding moiety comprises a protracting moiety selected from: HOOC—(CH2)x—CO—*??Chem. 1: HOOC—C6H4—O—(CH2)y—CO—*??Chem. 2: R1—C6H4—(CH2)z—CO—*??Chem. 3: HOOC—C4SH2—(CH2)w—CO—*??Chem. 4: in which x is an integer in the range of 6-18, y is an integer in the range of 3-17, z is an integer in the range of 1-5, R1 is a group having a molar mass not higher than 150 Da, and w is an integer in the range of 6-18; with the proviso that when the protracting moiety is Chem.
    Type: Application
    Filed: December 16, 2010
    Publication date: July 7, 2011
    Applicant: NOVO NORDISK A/S
    Inventors: PATRICK WILLIAM GARIBAY, JANE SPETZLER, JÁNOS TIBOR KODRA, LARS LINDEROTH, JESPER LAU, PER SAUERBERG