Abstract: A photon-number resolving (PNR) method and system are described. A PNR detector is calibrated to generate a characteristic pulse plot for each of a plurality of unique photon numbers. A generic tail portion is also stored. A signal is then detected through the PNR detector. The signal includes at least a first pulse and a second pulse, where the second pulse at least partially overlaps with the first pulse. The first photon number of the first pulse may be determined. Then, the characteristic pulse plot that corresponds to the first photon number is subtracted from the first pulse, such that the second photon number of the second pulse may be determined with minimized interference from any signal overlap. The generic tail portion may be scaled and subtracted from any identified stray events to minimize interference of stray signals from unintended light sources.

Abstract: There is described a device and method for utilizing an integrated multiplexer to perform additional functionalities other than signal routing using one or more interleaved input signals. Each interleaved signal includes a data signal interleaved with a proxy signal. In between routing operations of the data signal, the proxy signal from each interleaved signal can be routed to perform phase locking and/or switch bias locking. The routed proxy signal can be interfered with a global reference signal to produce a beat signal, the phase of which can be used to generate a feedback signal to maintain a desired phase relation between the data signal and the global reference signal. The signal strength of the routed proxy signal can also be detected so that a dithering technique may be used to adjust a bias voltage to the MUX switch to maintain an optimal operating state.

Abstract: A photon-number resolving (PNR) method and system are described. A PNR detector is calibrated to generate a characteristic pulse plot for each of a plurality of unique photon numbers. A generic tail portion is also stored. A signal is then detected through the PNR detector. The signal includes at least a first pulse and a second pulse, where the second pulse at least partially overlaps with the first pulse. The first photon number of the first pulse may be determined. Then, the characteristic pulse plot that corresponds to the first photon number is subtracted from the first pulse, such that the second photon number of the second pulse may be determined with minimized interference from any signal overlap. The generic tail portion may be scaled and subtracted from any identified stray events to minimize interference of stray signals from unintended light sources.

Abstract: This invention relates to novel compounds useful as potassium channel modulators. More specifically the invention provides chemical compounds useful as modulators of SKCa and/or IKCa channels.

Abstract: The present invention provides novel benzimidazol-2-one derivatives useful as therapeutic agents.

Abstract: The present invention relates to the use certain compounds for the treatment, prevention or alleviation of a disorder or disease of a subject, which disorder or disease is responsive to modulation of the mast cell or basophil activity of such a subject.