Abstract: The invention relates to compounds capable of inhibiting the visual cycle and/or dark adaptation and their use for treatment and prevention of non-degenerative retinal diseases with specific emphasis on the prevention and treatment of diabetic retinopathy, retinopathy of prematurity, branch retinal vein occlusion, central retinal vein occlusion, open-angle glaucoma, veovascular glaucoma, and other diseases of the retinal and/or optic nerve where an imbalance between metabolic demand and blood supply contribute to the development of tissue damage. The invention furthermore relates to pharmaceutical compositions comprising such compounds.

Abstract: The invention related to a method and a system for non- or minimally disruptive photomanipulation of the lens and/or its constituents collectively or selectively of an animal or human eye, comprising focusing a treatment laser beam into a selected part of the lens and/or its constituents collectively or selectively where treatment is intended to occur, pulsing of said treatment laser beam, scanning the beam over at least a part of the lens, measuring one or more types of radiation from the said selected part and utilizing this measurement to decide to stop the said treatment laser beam or to adjust at least one of the parameters: focus, intensity, wavelength, pulse length, repetition frequency, pulse train length, scan velocity, size of scanned volume, scan repetitions, and scan pattern of said treatment laser beam.

Abstract: The invention related to a method and a system for non- or minimally disruptive photomanipulation of the lens and/or its constituents collectively or selectively of an animal or human eye, comprising focusing a treatment laser beam into a selected part of the lens and/or its constituents collectively or selectively where treatment is intended to occur, pulsing of said treatment laser beam, scanning the beam over at least a part of the lens, measuring one or more types of radiation from the said selected part and utilizing this measurement to decide to stop the said treatment laser beam or to adjust at least one of the parameters: focus, intensity, wavelength, pulse length, repetition frequency, pulse train length, scan velocity, size of scanned volume, scan repetitions, and scan pattern of said treatment laser beam.