Publication number: 20070275962
Abstract: Described are heterobicyclic compounds such as 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]thiopyran 3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid amides, or benzo[b]thiophene-3-carboxylic acid amides and pharmaceutically acceptable salts thereof, the use of these derivatives for the prophylaxis and/or treatment of various diseases such as infectious diseases, including mycobacteriainduced infections and opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, as well as compositions containing at least one heterobicyclic compound and/or pharmaceutically acceptable salts thereof. Furthermore, reaction procedures for the synthesis of the heterobicyclic compound are disclosed.
Type:
Application
Filed:
September 10, 2004
Publication date:
November 29, 2007
Applicant:
GPC BIOTECH AG
Inventors:
Anil Koul, Bert Klebl, Gerhard Muller, Andrea Missio, Wilfried Schwab, Doris Hafenbradl, Lars Neumann, Marc-Nicola Sommer, Stefan Muller, Edmund Hoppe, Achim Freisleben, Alexander Backes, Christian Hartung, Beatrice Felber, Birgit Zech, Ola Engkvist, Gyorgy Keri, Laszlo Orfi, Peter Banhegyi, Zoltan Greff, Zoltan Horvath, Zoltan Varga, Peter Marko, Janos Pato, Istvan Szabadkai, Zsolt Szekelyhid, Frigyes Waczek