Patents by Inventor Lars ØSTERGAARD

Lars ØSTERGAARD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies specific for hyperphosphorylated tau and methods of use thereof
    Patent number: 11739140
    Abstract: The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: August 29, 2023
    Assignee: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Lars Østergaard Pedersen, Justus Claus Alfred Daechsel, Ayodeji Abdur-rasheed Asuni, Nina Helen Rosenqvist, Christiane Volbracht, Lone Helboe, Anders Brandt Elvang, Florence Sotty, Søren Christensen, Jeffrey B. Stavenhagen
  • Method for manufacturing a can
    Patent number: 11512702
    Abstract: A submersible pump assembly includes an electric motor (1) and a centrifugal pump, which is driven by the electric motor (1). A rotor (4) formed of plastic or composite material which is manufactured in the extrusion or pultrusion method.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: November 29, 2022
    Assignee: GRUNDFOS HOLDING A/S
    Inventors: Allan Hjarbæk Holm, Morten Vammen Ørsnæs, Lars Østergaard
  • ANTIBODIES SPECIFIC FOR HYPERPHOSPHORYLATED TAU AND METHODS OF USE THEREOF
    Publication number: 20220177557
    Abstract: The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PH F) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
    Type: Application
    Filed: August 11, 2021
    Publication date: June 9, 2022
    Applicant: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Kristian Kjaergaard, Lars Østergaard Pedersen, Ayodeji Abdur-Rasheed Asuni, Nina Helen Rosenqvist, Justus Claus Alfred Daechsel, Karsten Juhl, Lena Tagmose, Mauro Marigo, Thomas Jensen, Søren Christensen, Laurent David, Christiane Volbracht, Lone Helboe
  • Antibodies specific for hyperphosphorylated tau and methods of use thereof
    Patent number: 11111290
    Abstract: The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: September 7, 2021
    Assignee: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Kristian Kjaergaard, Lars Østergaard Pedersen, Ayodeji Abdur-Rasheed Asuni, Nina Helen Rosenqvist, Justus Claus Alfred Daechsel, Karsten Juhl, Lena Tagmose, Mauro Marigo, Thomas Jensen, Søren Christensen, Laurent David, Christiane Volbracht, Lone Helboe
  • ANTIBODIES SPECIFIC FOR HYPERPHOSPHORYLATED TAU AND METHODS OF USE THEREOF
    Publication number: 20210206843
    Abstract: The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.
    Type: Application
    Filed: January 8, 2021
    Publication date: July 8, 2021
    Applicant: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Lars Østergaard Pedersen, Justus Claus Alfred Daechsel, Ayodeji Abdur-rasheed Asuni, Nina Helen Rosenqvist, Christiane Volbracht, Lone Helboe, Anders Brandt, Florence Sotty, Søren Christensen, Jeffrey B. Stavenhagen
  • Antibodies specific for hyperphosphorlated tau for the treatment of ocular diseases
    Patent number: 10995137
    Abstract: The present invention is based on antibodies which are both highly specific for hyperphosphorylated pathogenic P-S396 tau and highly specific for labelled sections of the human retina, as well as to methods of using these antibodies and their tau binding fragments in the treatment of retinoid amyloidosis, age related macular degeneration (ARMD), and glaucoma.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: May 4, 2021
    Assignee: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Lars Østergaard Pedersen, Justus Claus Daechsel, Ayodeji Abdur-Rasheed Asuni, Nina Helen Rosenqvist
  • Submersible downhole pump
    Patent number: 10989199
    Abstract: A submersible downhole pump (1) includes an elongate pump unit (3) defining a longitudinal pump axis (L) and a pump unit diameter (D), and at least one cable lug (13) for attaching a cable. The at least one cable lug (13) is connected to the pump unit (3) and pivotable around a pivot axis (P) perpendicular to the longitudinal axis (L) between a defined first position and a defined second position. The at least one cable lug (13) is positioned, in the first position, fully within the pump unit diameter (D). In the second position, the at least one cable lug (13) is positioned at least partially protruding outside the pump unit diameter (D).
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: April 27, 2021
    Assignee: GRUNDFOS HOLDING A/S
    Inventors: Lars Østergaard, Brian Nonbo Jensen
  • Antibodies specific for hyperphosphorylated tau and methods of use thereof
    Patent number: 10934348
    Abstract: The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: March 2, 2021
    Assignee: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Lars Østergaard Pedersen, Justus Claus Alfred Daechsel, Ayodeji Abdur-rasheed Asuni, Nina Helen Rosenqvist, Christiane Volbracht, Lone Helboe, Anders Brandt Elvang, Florence Sotty, Søren Christensen, Jeffrey B. Stavenhagen
  • METHOD FOR MANUFACTURING A CAN
    Publication number: 20210010476
    Abstract: A submersible pump assembly includes an electric motor (1) and a centrifugal pump, which is driven by the electric motor (1). A rotor (4) formed of plastic or composite material which is manufactured in the extrusion or pultrusion method.
    Type: Application
    Filed: July 9, 2020
    Publication date: January 14, 2021
    Inventors: Allan Hjarbæk HOLM, Morten Vammen ØRSNÆS, Lars ØSTERGAARD
  • ANTIBODIES SPECIFIC FOR HYPERPHOSPHORYLATED TAU AND METHODS OF USE THEREOF
    Publication number: 20200190178
    Abstract: The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.
    Type: Application
    Filed: December 20, 2019
    Publication date: June 18, 2020
    Inventors: Jan Torleif Pedersen, Lars Østergaard Pedersen, Justus Claus Alfred Daechsel, Ayodeji Abdur-rasheed Asuni, Nina Helen Rosenqvist, Christiane Volbracht, Lone Helboe, Anders Brandt Elvang, Florence Sotty, Søren Christensen, Jeffrey B. Stavenhagen
  • Antibodies specific for hyperphosphorylated tau and methods of use thereof
    Patent number: 10647762
    Abstract: The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: May 12, 2020
    Assignee: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Kristian Kjaergaard, Lars Østergaard Pedersen, Abdur-Rasheed Asuni, Nina Helen Rosenqvist, Justus Claus Daechsel, Karsten Juhl, Lena Tagmose, Mauro Marigo, Thomas Jensen, Søren Christensen, Laurent David, Christiane Volbracht, Lone Helboe
  • ANTIBODIES SPECIFIC FOR HYPERPHOSPHORYLATED TAU AND METHODS OF USE THEREOF
    Publication number: 20200109192
    Abstract: The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PH F) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
    Type: Application
    Filed: September 27, 2019
    Publication date: April 9, 2020
    Inventors: Jan Torleif Pedersen, Kristian Kjaergaard, Lars Østergaard Pedersen, Ayodeji Abdur-Rasheed Asuni, Nina Helen Rosenqvist, Justus Claus Alfred Daechsel, Karsten Juhl, Lena Tagmose, Mauro Marigo, Thomas Jensen, Søren Christensen, Laurent David, Christiane Volbracht, Lone Helboe
  • Antibodies specific for hyperphosphorylated tau and methods of use thereof
    Patent number: 10562962
    Abstract: The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: February 18, 2020
    Assignee: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Lars Østergaard Pedersen, Justus Claus Daechsel, Ayodeji Abdur-rasheed Asuni, Nina Helen Rosenqvist, Christiane Volbracht, Lone Helboe, Anders Brandt Elvang, Florence Sotty, Søren Christensen, Jeffrey B. Stavenhagen
  • Antibodies specific for hyperphosphorylated tau and methods of use thereof
    Patent number: 10487142
    Abstract: The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: November 26, 2019
    Assignee: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Kristian Kjaergaard, Lars Østergaard Pedersen, Abdur-Rasheed Asuni, Nina Helen Rosenqvist, Justus Claus Daechsel, Karsten Juhl, Lena Tagmose, Mauro Marigo, Thomas Jensen, Søren Christensen, Laurent David, Christiane Volbracht, Lone Helboe
  • Antibodies specific for hyperphosphorylated tau and methods of use
    Patent number: 10472415
    Abstract: The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: November 12, 2019
    Assignee: H. Lundbeck A/S
    Inventors: Jan Torleif Pedersen, Kristian Kjærgaard, Lars Østergaard Pedersen, Abdur-Rasheed Asuni, Nina Helen Rosenqvist, Justus Claus Alfred Daechsel, Karsten Juhl, Lena Tagmose, Mauro Marigo, Thomas Jensen, Søren Christensen, Laurent David, Christiane Volbracht, Lone Helboe
  • ANTIBODIES SPECIFIC FOR HYPERPHOSPHORLATED TAU FOR THE TREATMENT OF OCULAR DISEASES
    Publication number: 20190330320
    Abstract: The present invention is based on antibodies which are both highly specific for hyperphosphorylated pathogenic P-S396 tau and highly specific for labelled sections of the human retina, as well as to methods of using these antibodies and their tau binding fragments in the treatment of retinoid amyloidosis, age related macular degeneration (ARMD), and glaucoma.
    Type: Application
    Filed: January 3, 2018
    Publication date: October 31, 2019
    Inventors: Jan Torleif Pedersen, Lars Østergaard Pedersen, Justus Claus Daechsel, Ayodeji Abdur-Rasheed Asuni, Nina Helen Rosenqvist
  • Fan cooled dual-compartment electronic housing for an electric motor
    Patent number: 10439475
    Abstract: An electric motor with a stator housing (2) and with an electronics housing (8), has a first section (A) of the electronics housing arranged on the radial side of the stator housing (2), and a fan (24) arranged on a first axial end (22) of the stator housing (2). The electronics housing (8) extends in the axial direction (X) beyond the first axial end (22) of the stator housing in a manner such that a second section (B) of the electronics housing (8), in whose inside at least one first heat-producing electronic component (58, 60) is arranged, is situated on the radial side of the fan (24). A pump assembly with such an electric motor is also provided.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: October 8, 2019
    Assignee: GRUNDFOS HOLDING A/S
    Inventors: Palle Madsen Obel, Lars Østergaard
  • ANTIBODIES SPECIFIC FOR HYPERPHOSPHORYLATED TAU AND METHODS OF USE THEREOF
    Publication number: 20190284265
    Abstract: The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
    Type: Application
    Filed: April 1, 2019
    Publication date: September 19, 2019
    Inventors: Jan Torleif Pedersen, Kristian Kjaergaard, Lars Østergaard Pedersen, Abdur-Rasheed Asuni, Nina Helen Rosenqvist, Justus Claus Daechsel, Karsten Juhl, Lena Tagmose, Mauro Marigo, Thomas Jensen, Søren Christensen, Laurent David, Christiane Volbracht, Lone Helboe
  • ANTIBODIES SPECIFIC FOR HYPERPHOSPHORYLATED TAU AND METHODS OF USE THEREOF
    Publication number: 20190284266
    Abstract: The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396) with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
    Type: Application
    Filed: April 1, 2019
    Publication date: September 19, 2019
    Inventors: Jan Torleif Pedersen, Kristian Kjaergaard, Lars Østergaard Pedersen, Abdur-Rasheed Asuni, Nina Helen Rosenqvist, Justus Claus Daechsel, Karsten Juhl, Lena Tagmose, Mauro Marigo, Thomas Jensen, Søren Christensen, Laurent David, Christiane Volbracht, Lone Helboe
  • ABETA VARIANTS, ASSAY, METHOD AND TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20190275125
    Abstract: The present invention relates to a new abeta immunogen variants that enables efficient treatment of Alzheimer's Disease patients by raising specific antibodies against oligimeric and toxic abeta deposits in the brain of Alzheimer's patients.
    Type: Application
    Filed: March 7, 2019
    Publication date: September 12, 2019
    Inventors: Lars Østergaard Pedersen, Dorte Kornerup Ditlevsen