Patents by Inventor Lars Stockl

Lars Stockl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR PREPARING SURFACTANT PROTEIN D (SP-D)
    Publication number: 20220042036
    Abstract: Some embodiments of the methods and compositions provided herein relate to the preparation surfactant protein-D (SP-D). Some embodiments include the expression of human SP-D in certain cell lines, and the purification of human SP-D from such cell lines. Some embodiments include the preparation of certain oligomeric forms of human SP-D.
    Type: Application
    Filed: March 25, 2021
    Publication date: February 10, 2022
    Inventors: Jan Susan Rosenbaum, Frederick Gyapon Quast, Matthias Kaup, Lars Stöckl
  • Methods and compositions for preparing surfactant protein D (SP-D)
    Patent number: 10975389
    Abstract: Some embodiments of the methods and compositions provided herein relate to the preparation surfactant protein-D (SP-D). Some embodiments include the expression of human SP-D in certain cell lines, and the purification of human SP-D from such cell lines. Some embodiments include the preparation of certain oligomeric forms of human SP-D.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: April 13, 2021
    Assignee: Airway Therapeutics, Inc.
    Inventors: Jan Susan Rosenbaum, Frederick Gyapon Quast, Matthias Kaup, Lars Stöckl
  • METHODS, COMPOSITIONS AND CELLS FOR PREPARING SURFACTANT PROTEIN D (SP-D)
    Publication number: 20200407747
    Abstract: Some embodiments of the methods and compositions provided herein relate to the preparation surfactant protein-D (SP-D). Some embodiments include the expression of human SP-D in certain cell lines, and the purification of human SP-D from such cell lines. Some embodiments include the preparation of certain oligomeric forms of human SP-D.
    Type: Application
    Filed: July 16, 2020
    Publication date: December 31, 2020
    Inventors: Jan Susan Rosenbaum, Frederick Gyapon Quast, Matthias Kaup, Lars Stöckl
  • Methods, compositions and cells for preparing surfactant protein D (SP-D)
    Patent number: 10752914
    Abstract: Some embodiments of the methods and compositions provided herein relate to the preparation surfactant protein-D (SP-D). Some embodiments include the expression of human SP-D in certain cell lines, and the purification of human SP-D from such cell lines. Some embodiments include the preparation of certain oligomeric forms of human SP-D.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: August 25, 2020
    Assignees: Airway Therapeutics, Inc., Glycotope GmbH
    Inventors: Jan Susan Rosenbaum, Frederick Gyapon Quast, Matthias Kaup, Lars Stöckl
  • METHODS AND COMPOSITIONS FOR PREPARING SURFACTANT PROTEIN D (SP-D)
    Publication number: 20190071694
    Abstract: Some embodiments of the methods and compositions provided herein relate to the preparation surfactant protein-D (SP-D). Some embodiments include the expression of human SP-D in certain cell lines, and the purification of human SP-D from such cell lines. Some embodiments include the preparation of certain oligomeric forms of human SP-D.
    Type: Application
    Filed: September 4, 2018
    Publication date: March 7, 2019
    Inventors: Jan Susan Rosenbaum, Frederick Gyapon Quast, Matthias Kaup, Lars Stöckl
  • METHODS, COMPOSITIONS AND CELLS FOR PREPARING SURFACTANT PROTEIN D (SP-D)
    Publication number: 20190071693
    Abstract: Some embodiments of the methods and compositions provided herein relate to the preparation surfactant protein-D (SP-D). Some embodiments include the expression of human SP-D in certain cell lines, and the purification of human SP-D from such cell lines. Some embodiments include the preparation of certain oligomeric forms of human SP-D.
    Type: Application
    Filed: September 4, 2018
    Publication date: March 7, 2019
    Inventors: Jan Susan Rosenbaum, Frederick Gyapon Quast, Matthias Kaup, Lars Stöckl
  • CONTROLLED OVARIAN HYPERSTIMULATION WITH IMPROVED RECOMBINANT HUMAN FOLLICLE-STIMULATING HORMONE
    Publication number: 20170035854
    Abstract: The present invention pertains to methods for controlled ovarian hyperstimulation in a female subject using improved recombinant human follicle-stimulating hormone (rhFSH). The methods result in a high number of fertilizable oocytes even at low amounts of FSH administered to the female subject.
    Type: Application
    Filed: April 17, 2015
    Publication date: February 9, 2017
    Inventors: Steffen GOLETZ, Lars STÖCKL
  • Recombinant human follicle-stimulating hormone
    Patent number: 9527899
    Abstract: The present invention pertains to improved FSH preparations which are capable of stimulating sex steroid release at much lower concentration than the commonly used urinary FSH or recombinant FSH obtained from CHO cells and which act independent of cAMP signaling These improved FSH preparations can be used in infertility treatment.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: December 27, 2016
    Assignee: Glycotope GmbH
    Inventors: Steffen Goletz, Lars Stöckl
  • Use of human cells of myeloid leukaemia origin for expression of antibodies
    Patent number: 9051356
    Abstract: The invention relates to a method for producing a protein molecule composition having a defined glycosylation pattern, comprising (a) introducing in a host cell which is an immortalized human blood cell at least one nucleic acid encoding at least a part of said protein; and (b) culturing said host cell under conditions which permit the production of said protein molecule composition; and (c) isolating said protein molecule composition.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: June 9, 2015
    Assignee: Glycotope GmbH
    Inventors: Steffen Goletz, Antje Danielczyk, Hans Baumeister, Renate Stahn, Anja Löffler, Lars Stöckl
  • Process for the purification of glycoproteins
    Patent number: 8846344
    Abstract: The present invention relates to a process for the purification of a glycoprotein comprising subjecting a liquid containing said glycoprotein to the steps of: a) reverse phase chromatography, b) size exclusion chromatography, and c) hydrophobic interaction chromatography. Also provided is a manufacturing process for producing a glycoprotein of interest.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: September 30, 2014
    Assignee: Glycotope GmbH
    Inventors: Steffen Goletz, Lars Stockl
  • RECOMBINANT HUMAN FOLLICLE-STIMULATING HORMONE
    Publication number: 20130137636
    Abstract: The present invention pertains to improved FSH preparations which are capable of stimulating sex steroid release at much lower concentration than the commonly used urinary FSH or recombinant FSH obtained from CHO cells and which act independent of cAMP signaling These improved FSH preparations can be used in infertility treatment.
    Type: Application
    Filed: August 4, 2011
    Publication date: May 30, 2013
    Applicant: GLYCOTOPE GMBH
    Inventors: Steffen Goletz, Lars Stockl
  • PROCESS FOR THE PURIFICATION OF GLYCOPROTEINS
    Publication number: 20120329092
    Abstract: The present invention relates to a process for the purification of a glycoprotein comprising subjecting a liquid containing said glycoprotein to the steps of: a) reverse phase chromatography, b) boronate affinity chromatography, and c) size exclusion chromatography. Also provided is a manufacturing process for producing a glycoprotein of interest.
    Type: Application
    Filed: January 25, 2011
    Publication date: December 27, 2012
    Applicant: Glycotope GmbH
    Inventors: Steffen Goletz, Lars Stöckl
  • PROCESS FOR THE PURIFICATION OF GLYCOPROTEINS
    Publication number: 20120252069
    Abstract: The present invention relates to a process for the purification of a glycoprotein comprising subjecting a liquid containing said glycoprotein to the steps of: a) reverse phase chromatography, b) size exclusion chromatography, and c) hydrophobic interaction chromatography. Also provided is a manufacturing process for producing a glycoprotein of interest.
    Type: Application
    Filed: November 24, 2010
    Publication date: October 4, 2012
    Applicant: GLYCOTOPE GmbH
    Inventors: Steffen Goletz, Lars Stockl
  • USE OF HUMAN CELLS OF MYELOID LEUKAEMIA ORIGIN FOR EXPRESSION OF ANTIBODIES
    Publication number: 20100028947
    Abstract: The invention relates to a method for producing a protein molecule composition having a defined glycosylation pattern, comprising (a) introducing in a host cell which is an immortalized human blood cell at least one nucleic acid encoding at least a part of said protein; and (b) culturing said host cell under conditions which permit the production of said protein molecule composition; and (c) isolating said protein molecule composition.
    Type: Application
    Filed: September 10, 2007
    Publication date: February 4, 2010
    Inventors: Steffen Goletz, Antje Danielczyk, Hans Baumeister, Renate Stahn, Anja Löffler, Lars Stöckl