Patents by Inventor Lars Stubberud

Lars Stubberud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Contrast agents
    Publication number: 20070014731
    Abstract: The present invention provides contrast agents for use in diagnostic ultrasound studies comprising microbubbles of gas or a gas precursor encapsulated by non-proteinaceous crosslinked or polymerised amphiphilic moieties.
    Type: Application
    Filed: May 17, 2006
    Publication date: January 18, 2007
    Inventors: Jo Klaveness, Hanno Priebe, Pal Rongved, Lars Stubberud
  • Contrast agents
    Publication number: 20050196342
    Abstract: Contrast agents comprising microbubble-generating carbohydrate microparticles having a surfactant admixed within the microparticulate structure, with the proviso that the surfactant is not a C10-20 fatty acid, are disclosed. Processes for preparing contrast agents also are disclosed.
    Type: Application
    Filed: February 10, 2005
    Publication date: September 8, 2005
    Inventors: Jo Klaveness, Pal Rongved, Lars Stubberud
  • Contrast agents
    Publication number: 20050031543
    Abstract: Contrast agents comprising microbubble-generating carbohydrate microparticles having a surfactant admixed within the microparticulate structure, with the proviso that the surfactant is not a C10-20 fatty acid, are disclosed. Processes for preparing contrast agents also are disclosed.
    Type: Application
    Filed: April 7, 2004
    Publication date: February 10, 2005
    Inventors: Jo Klaveness, Pal Rongved, Lars Stubberud
  • Contrast agents
    Publication number: 20040131548
    Abstract: The present invention provides contrast agents for use in diagnostic ultrasound studies comprising microbubbles of gas or a gas precursor encapsulated by non-proteinaceous crosslinked or polymerised amphiphilic moieties.
    Type: Application
    Filed: May 29, 2003
    Publication date: July 8, 2004
    Applicant: Amersham Health AS
    Inventors: Jo Klaveness, Hanno Priebe, Pal Rongved, Lars Stubberud
  • Contrast agents
    Publication number: 20030059373
    Abstract: Contrast agents comprising microbubble-generating carbohydrate microparticles having a surfactant admixed within the microparticulate structure, with the proviso that the surfactant is not a C10-20 fatty acid, are disclosed. Processes for preparing contrast agents also are disclosed.
    Type: Application
    Filed: February 8, 2002
    Publication date: March 27, 2003
    Applicant: Nycomed Imaging AS
    Inventors: Jo Klaveness, Pal Rongved, Lars Stubberud
  • Contrast agents
    Publication number: 20020172643
    Abstract: The present invention provides contrast agents for use in diagnostic ultrasound studies comprising microbubbles of gas or a gas precursor encapsulated by non-proteinaceous crosslinked or polymerised amphiphilic moieties.
    Type: Application
    Filed: August 10, 2001
    Publication date: November 21, 2002
    Applicant: Nycomed Imaging AS
    Inventors: Jo Klaveness, Hanno Priebe, Pal Rongved, Lars Stubberud
  • Microbubble-containing contrast agents having a non-proteinaceous crosslinked or polymerised amphiphilic shell
    Patent number: 6106806
    Abstract: Ultrasound contrast agents having microbubbles of gas or a gas precursor encapsulated by non-proteinaceous crosslinked or polymerised amphiphilic moieties, e.g. in the form of micelles, exhibit good stability in vivo upon administration and may if desired incorporate biodegradable linkages so as to possess particular desired levels of biodegradability.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 22, 2000
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, Hanno Priebe, P.ang.l Rongved, Lars Stubberud, Roald Skurtveit, Harald Dugstad
  • Contrast agents, consisting of carbohydrate particles
    Patent number: 5928626
    Abstract: The present invention relates to contrast agents comprising water-soluble microbubble-generating carbohydrate microparticles in admixture with at least 10% w/w relative to the overall composition of a non-surface active material which is less water soluble than the carbohydrate. The contrast agents exhibit useful levels of contrast efficiency and/or stability and may be used in diagnostic applications such as ultrasound and MR imaging.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: July 27, 1999
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, P.ang.l Rongved, Lars Stubberud
  • Microparticulate microbubble-generating contrast agents
    Patent number: 5827502
    Abstract: The present invention relates to contrast agents comprising microbubble-generating carbohydrate particles having a surfactant admixed within the microparticulate structure, wherein the microbubbles generated by the microparticles comprise a biocompatible low molecular weight fluorinated hydrocarbon. The contrast agents exhibit useful levels of contrast efficiency and/or stability and may be used in diagnostic applications such as ultrasound and MR imaging.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 27, 1998
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, Pal Rongved, Lars Stubberud
  • Pharmaceutical preparation
    Patent number: 5783215
    Abstract: Controlled release beads containing a core around which is a drug-containing layer e.g. a layer containing furosemid and a process for their preparation and their use in a pharmaceutical preparation. The controlled release beads have excellent mechanical and release characteristics.
    Type: Grant
    Filed: June 22, 1995
    Date of Patent: July 21, 1998
    Assignee: Astra Aktiebolag
    Inventors: Hans Arwidsson, Lars Stubberud
  • Method of ultrasound imaging using microbubble-forming, solid X-ray contrast agents
    Patent number: 5772984
    Abstract: Ultrasound contrast agents comprising a microbubble-generating suspension of a microparticulate X-ray contrast agent in a liquid carrier medium.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 30, 1998
    Assignee: Nycomed Imaging AS
    Inventors: Arne Berg, Jo Klaveness, Per Strande, Lars Stubberud
  • Contrast agents consisting of galactose particles
    Patent number: 5648062
    Abstract: Water soluble microbubble generating microparticle contrast agents which are comprised of a carbohydrate and a non-triglyceride, non-surface active material for use in image enhancement wherein the non-surface active material is less soluble in water than the carbohydrate.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 15, 1997
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, Pal Rongveo, Lars Stubberud
  • Contrast agents, consisting of galactose particles
    Patent number: 5637289
    Abstract: The present invention relates to contrast agents comprising water-soluble microbubble-generating carbohydrate microparticles in admixture with at least 10% w/w relative to the overall composition of a non-surface active material which is less water soluble than the carbohydrate. The contrast agents exhibit useful levels of contrast efficiency and/or stability and may be used in diagnostic applications such as ultrasound and MR imaging.
    Type: Grant
    Filed: November 1, 1994
    Date of Patent: June 10, 1997
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, P.ang.l Rongveo, Lars Stubberud
  • Contrast agents, consisting of galactose particles and an amphilic carboxylic acid
    Patent number: 5614169
    Abstract: The present invention relates to contrast agents comprising microbubble-generating carbohydrate microparticles in admixture with an amphiphilic organic acid containing in excess of 20 carbon atoms. The contrast agents exhibit good stability and/or enhanced contrast effect and may be used in diagnostic applications such as ultrasound and MR imaging.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: March 25, 1997
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, P.ang.l Rongved, Lars Stubberud
  • Aggregates of x-ray microparticles for ultrasound imaging
    Patent number: 5607661
    Abstract: The invention relates to ultrasound contrast agents comprising a microbubble-generating suspension of a microparticulate X-ray contrast agent in a liquid carrier medium.
    Type: Grant
    Filed: February 9, 1994
    Date of Patent: March 4, 1997
    Assignee: Nycomed Imaging AS
    Inventors: Arne Berg, Jo Klaveness, Per Strande, Lars Stubberud
  • Flexible amphiphilic microbubbles for ultrasound
    Patent number: 5567413
    Abstract: The invention relates to diagnostic ultrasound contrast agents comprising vesicles comprising an amphiphilic phospholipid material capable of formation of gas-containing vesicles wherein the vesicles contain gas which comprises a low molecular weight fluorinated hydrocarbon.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 22, 1996
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, Hanno Priebe, P.ang.l Rongved, Lars Stubberud
  • Contrast agents consisting of galactose particles and an amphilic carboxylic acid
    Patent number: 5567412
    Abstract: The present invention relates to contrast agents comprising microbubble-generating carbohydrate microparticles in admixture with an amphiphilic organic acid containing in excess of 20 carbon atoms. The contrast agents exhibit good stability and/or enhanced contrast effect and may be used in diagnostic applications such as ultrasound and MR imaging.
    Type: Grant
    Filed: September 29, 1994
    Date of Patent: October 22, 1996
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, P.ang.l Rongved, Lars Stubberud
  • Microbubble-generating contrast agents for ultrasound and magnetic resonance imaging
    Patent number: 5558856
    Abstract: The present invention relates to contrast agents comprising microbubble-generating carbohydrate particles having a surfactant admixed within the microparticulate structure, with the proviso that the surfactant is not a saturated C.sub.10-20 fatty acid. The contrast agents exhibit useful levels of contrast efficiency and/or stability and may be used in diagnostic applications such as ultrasound and MR imaging.
    Type: Grant
    Filed: December 9, 1994
    Date of Patent: September 24, 1996
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, Pal Rongved, Lars Stubberud
  • Contrast agents
    Patent number: 5536490
    Abstract: The invention relates to diagnostic ultrasound contrast agents comprising vesicles comprising an amphiphilic phospholipid material capable of formation of gas-containing vesicles wherein the vesicles contain gas which comprises sulphur hexafluoride. The contrast agents and vesicles exhibit good stability in vivo upon administration and may if desired incorporate biodegradable linkages so as to possess particularly desired levels of biodegradability.
    Type: Grant
    Filed: October 29, 1993
    Date of Patent: July 16, 1996
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, Hanno Priebe, Pal Rongved, Lars Stubberud