Patents by Inventor Lars Swanson

Lars Swanson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-phenyl-3-methoxy-pyrrolidine derivatives useful as modulators of cortical catecholaminergic neurotransmission
    Patent number: 9035073
    Abstract: The present invention relates to novel 3-phenyl-3-methoxy-pyrrolidine derivatives, useful for modulating extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-3-methoxy-pyrrolidine derivatives of the invention and to the use of these compounds for therapeutic applications.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: May 19, 2015
    Assignee: Integrative Research Laboratories Sweden AB
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson
  • 3-PHENYL-3-METHOXY-PYRROLIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION
    Publication number: 20140135505
    Abstract: The present invention relates to novel 3-phenyl-3-methoxy-pyrrolidine derivatives, useful for modulating extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-3-methoxy-pyrrolidine derivatives of the invention and to the use of these compounds for therapeutic applications.
    Type: Application
    Filed: January 22, 2014
    Publication date: May 15, 2014
    Applicant: INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB
    Inventors: Clas SONESSON, Lars SWANSON, Fredrik PETTERSSON
  • 3-phenyl-3-methoxypyrrolidine derivatives as modulators of cortical catecholaminergic neurotransmission
    Patent number: 8673962
    Abstract: The present invention relates to novel 3-phenyl-3-methoxy-pyrrolidine derivatives, useful for modulating extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-3-methoxy-pyrrolidine derivatives of the invention and to the use of these compounds for therapeutic applications.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: March 18, 2014
    Assignee: Integrative Research Laboratories Sweden AB
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson
  • 3-phenyl-azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission
    Patent number: 8586572
    Abstract: The present invention relates to novel 3-phenyl-azetidine derivatives, useful for modulating extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-azetidine derivatives of the invention and to the use of these compounds for therapeutic applications.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: November 19, 2013
    Assignee: Integrative Research Laboratories Sweden AB
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson
  • Disubstituted phenylpiperdines/piperazines as modulators of dopamine neurotransmission
    Patent number: 8314126
    Abstract: The present invention relates to compounds which have therapeutic effects against disorders in the central nervous system, and in particular new 4-(ortho,meta-disubstituted phenyl)-1-alkypiperidines and piperazines. wherein R1, R2, R3 and X are as defined.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: November 20, 2012
    Assignee: NSAB, Filial af Neurosearch Sweden AB, Sverige
    Inventors: Clas Sonesson, Lars Swanson, Nicholas Ross Waters
  • Disubstituted phenylpyrrolidines as modulators of cortical catecholaminergic neurotransmission
    Patent number: 8188301
    Abstract: The present invention relates to the use of compounds which increase extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically to the use of 3-disubstituted phenyl-1-pyrrolidinols for the treatment of central nervous system disorders.
    Type: Grant
    Filed: June 4, 2008
    Date of Patent: May 29, 2012
    Assignee: NSAB, Filial af NeuroSearch Sweden AB, Sverige
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson, Nicholas Waters, Susanna Waters
  • NOVEL 3-PHENYL-AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION
    Publication number: 20110281835
    Abstract: The present invention relates to novel 3-phenyl-azetidine derivatives, useful for modulating extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-azetidine derivatives of the invention and to the use of these compounds for therapeutic applications.
    Type: Application
    Filed: November 24, 2009
    Publication date: November 17, 2011
    Applicant: NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson
  • NOVEL 1-ALKYL-3-HYDROXY-3-PHENYLAZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION
    Publication number: 20110257148
    Abstract: The present invention relates to novel 3-phenyl-azetidine derivatives, useful for modulating dopamine neurotransmission and extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-azetidine derivatives of the invention and to the use of these compounds for therapeutic applications. X is OH; R1 is F or Cl; R2 is H, F or Cl; and R3 is n-Pr, i-Pr, n-Bu, i-Bu, s-Bu or t-Bu.
    Type: Application
    Filed: November 24, 2009
    Publication date: October 20, 2011
    Applicant: NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson
  • 3-PHENYL-3-METHOXYPYRROLIDINE DERIVATIVES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION
    Publication number: 20110257241
    Abstract: The present invention relates to novel 3-phenyl-3-methoxy-pyrrolidine derivatives, useful for modulating extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-3-methoxy-pyrrolidine derivatives of the invention and to the use of these compounds for therapeutic applications.
    Type: Application
    Filed: November 24, 2009
    Publication date: October 20, 2011
    Applicant: NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson
  • 3-PHENYL-3-METHOXYPYRROLIDINE DERIVATIVES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION
    Publication number: 20110257242
    Abstract: The present invention relates to novel 3-phenyl-3-methoxy-pyrrolidine derivatives, useful for modulating dopamine neurotransmission and extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically for the treatment of central nervous system disorders. In other aspects the invention relates to pharmaceutical compositions comprising the 3-phenyl-3-methoxy-pyrrolidine derivatives of the invention and to the use of these compounds for therapeutic applications.
    Type: Application
    Filed: November 24, 2009
    Publication date: October 20, 2011
    Applicant: NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson
  • Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
    Patent number: 7851629
    Abstract: The present invention relates to compounds which have therapeutic effects against disorders in the central nervous system, and in particular new 4-(ortho,meta-disubstituted phenyl)-1-alkypiperidines. wherein R1, R2, and R3 are as defined.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: December 14, 2010
    Assignee: NSAB, Filial af Neurosearch Sweden AB, Sverige
    Inventors: Clas Sonesson, Lars Swanson, Nicholas Ross Waters
  • DISUBSTITUTED PHENYLPIPERDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION
    Publication number: 20100256163
    Abstract: The present invention relates to compounds which have therapeutic effects against disorders in the central nervous system, and in particular new 4-(ortho,meta-disubstituted phenyl)-1-alkypiperidines and piperazines. wherein R1, R2, R3 and X are as defined.
    Type: Application
    Filed: June 14, 2010
    Publication date: October 7, 2010
    Inventors: Clas Sonesson, Lars Swanson, Nicholas Ross Waters
  • DISUBSTITUTED PHENYLPYRROLIDINES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION
    Publication number: 20100197760
    Abstract: The present invention provides compounds which increase extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically to the use of 3-(disubstituted aryl)-pyrrolidines for the treatment of central nervous system disorders.
    Type: Application
    Filed: June 4, 2008
    Publication date: August 5, 2010
    Applicant: NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson, Nicholas Waters, Susanna Waters
  • Disubstituted phenylpiperidines/piperazines as modulators of dopamine neurotransmission
    Patent number: 7763639
    Abstract: The present invention relates to compounds which have therapeutic effects against disorders in the central nervous system, and in particular new 4-(ortho, meta-disubstituted phenyl)-1-alkypiperidines and piperazines. wherein R1, R2, R3 and X are as defined.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: July 27, 2010
    Assignee: NSAB, Filial AF Neurosearch Sweden AB, Sverige
    Inventors: Clas Sonesson, Lars Swanson, Nicholas Ross Waters
  • DISUBSTITUTED PHENYLPYRROLIDINES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION
    Publication number: 20100179211
    Abstract: The present invention relates to the use of compounds which increase extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically to the use of 3-disubstituted phenyl-1-pyrrolidinols for the treatment of central nervous system disorders.
    Type: Application
    Filed: June 4, 2008
    Publication date: July 15, 2010
    Applicant: NSAB, FILIAL AF NEUROSEARCH SWEDEN AB
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson, Nicholas Waters, Susanna Waters
  • Substituted piperidines as modulators of dopamine neurotransmission
    Patent number: 7579474
    Abstract: The present invention relates to compounds having therapeutic effects against disorders in the central nervous system, and in particular substituted hydroxypiperidines of the formula 1: wherein R1, R2, and R3 are as defined herein.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: August 25, 2009
    Assignee: NSAB, Filial AF Neurosearch AB, Sverige
    Inventors: Clas Sonesson, Lars Swanson, Nicholas Waters
  • Method and use of acidified modified polymers to bind biocides in paints
    Patent number: 7531581
    Abstract: The invention herein relates to the method and use in an antifouling paint that specifically and efficiently impede settlement of for example barnacles on aquatic structures, using imidazole containing compound, such as Medetomidine, bound to a sulfonated, acid sulphate ester, phosphonic acid, carboxylic acid or acid phosphate ester modified polymer backbone such as polystyrene or acrylate polymers. The aim is to employ the biocide-polymer complexes as additives in a self-polishing paint for controlled release purposes.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: May 12, 2009
    Assignee: I-Tech AB
    Inventors: Magnus Nydén, Camilla Fant, Krister Holmberg, Lars Swanson
  • Disubstituted Phenylpiperidines as Modulators of Cortical Catecholaminergic Neurotransmission
    Publication number: 20080269286
    Abstract: The present invention relates to compounds of the formulae (4), (5) or (6), and their use in the treatment of central nervous system disorders.
    Type: Application
    Filed: December 6, 2006
    Publication date: October 30, 2008
    Inventors: Clas Sonesson, Lars Swanson, Fredrik Pettersson, Nicholas Waters, Susanna Waters
  • SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION
    Publication number: 20070270467
    Abstract: The present invention relates to compounds having therapeutic effects against disorders in the central nervous system, and in particular substituted hydroxypiperidines of the formula 1: wherein R1, R2, and R3 are as defined herein.
    Type: Application
    Filed: December 7, 2006
    Publication date: November 22, 2007
    Inventors: Clas Sonesson, Lars Swanson, Nicholas Waters
  • NEW DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF DOPAMINE AND SEROTONIN NEUROTRANSMISSION
    Publication number: 20070179185
    Abstract: The present invention relates to compounds which have therapeutic effects against disorders in the central nervous system, and in particular new 4-(ortho,meta-disubstituted phenyl)-1-alkypiperidines. wherein R1, R2, and R3 are as defined.
    Type: Application
    Filed: December 7, 2006
    Publication date: August 2, 2007
    Inventors: Clas Sonesson, Lars Swanson, Nicholas Waters