Patents by Inventor Lars Thelander

Lars Thelander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7157449
    Abstract: The present invention relates to the use of an inhibitor of CTP synthetase, such as a glutamine analogue, and a substance capable of suppressing toxic effects thereof in vivo, in the manufacture of a medicament for the treatment of a disease caused by a parasitic protozoa. More specifically, said substance capable of suppressing toxic effects may be a nucleobase, such as a purine base or a nucleoside, while the glutamine analogue advantageously is 6-diazo-5-oxo-L-norleucine (DON). The invention also relates to a pharmaceutical composition as such for the treatment and/or prevention of a disease caused by a parasitic protozoa, wherein the disease is selected from the group consisting of malaria, leishmaniasis and trypanosomiasis, e.g. American trypanosomiasis (Chaga's disease), or African trypanosomiasis (African sleeping sickness).
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: January 2, 2007
    Inventors: Anders Hofer, Lars Thelander
  • Publication number: 20030109505
    Abstract: The present invention relates to the use of an inhibitor of CTP synthetase, such as a glutamine analogue, and a substance capable of suppressing toxic effects thereof in vivo, in the manufacture of a medicament for the treatment of a disease caused by a parasitic protozoa. More specifically, said substance capable of suppressing toxic effects may be a nucleobase, such as a purine base or a nucleoside, while the glutamine analogue advantageously is 6-diazo-5-oxo-L-norleucine (DON). The invention also relates to a pharmaceutical composition as such for the treatment and/or prevention of a disease caused by a parasitic protozoa, wherein the disease is selected from the group consisting of malaria, leishmaniasis and trypanosomiasis, e.g. American trypanosomiasis (Chaga's disease), or African trypanosomiasis (African sleeping sickness).
    Type: Application
    Filed: October 28, 2002
    Publication date: June 12, 2003
    Inventors: Anders Hofer, Lars Thelander
  • Patent number: 4331662
    Abstract: Compositions for inhibiting cell growth, particularly compositions for the reatment of virus infections, are provided comprising the nucleoside 2'-azido-2'-desoxycytidine.
    Type: Grant
    Filed: February 4, 1980
    Date of Patent: May 25, 1982
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Fritz Eckstein, John B. Hobbs, Lambert Skoog, Gunnar Bjursell, Lars Thelander