Patents by Inventor Lars Vouilleme

Lars Vouilleme has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapy and kit for the prevention and treatment of cystic fibrosis
    Patent number: 9421239
    Abstract: A combination therapy and kit including an agent that inhibit the interaction between CAL and mutant CFTR proteins, in combination with a CFTR corrector, CFTR potentiator, mucolytic, anti-inflammatory agent or a combination thereof are provided as is a method for preventing or treating cystic fibrosis.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: August 23, 2016
    Assignee: TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguérin, Rudolf Volkmer, Lars Vouilleme
  • Combination therapy and kit for the prevention and treatment of cystic fibrosis
    Patent number: 9333235
    Abstract: A combination therapy and kit including an agent that inhibit the interaction between CAL and mutant CFTR proteins, in combination with a CFTR corrector, CFTR potentiator, mucolytic, anti-inflammatory agent or a combination thereof are provided as is a method for preventing or treating cystic fibrosis.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: May 10, 2016
    Assignee: Trustees of Dartmouth College
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguérin, Rudolf Volkmer, Lars Vouilleme
  • THERAPY AND KIT FOR THE PREVENTION AND TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20150250848
    Abstract: A combination therapy and kit including an agent that inhibit the interaction between CAL and mutant CFTR proteins, in combination with a CFTR corrector, CFTR potentiator, mucolytic, anti-inflammatory agent or a combination thereof are provided as is a method for preventing or treating cystic fibrosis.
    Type: Application
    Filed: May 22, 2015
    Publication date: September 10, 2015
    Applicant: Trustees of Dartmouth College
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguérin, Rudolf Volkmer, Lars Vouilleme
  • Compositions and methods for inhibiting the interaction between CFTR and CAL
    Patent number: 8999919
    Abstract: The present invention features compositions and methods for increasing the cell surface expression of degradation-prone CFTR proteins and preventing or treating cystic fibrosis. The invention provides peptides and peptidomimetics that selectively inhibit the interaction between CAL and mutant CFTR proteins, thereby stabilizing the CFTR and facilitating transport of the same to the cell surface.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: April 7, 2015
    Assignee: Trustees of Dartmouth College
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguearin, Rudolph Volkmer, Lars Vouilleme
  • COMBINATION THERAPY AND KIT FOR THE PREVENTION AND TREATMENT OF CYSTIC FIBROSIS
    Publication number: 20140100155
    Abstract: A combination therapy and kit including an agent that inhibit the interaction between CAL and mutant CFTR proteins, in combination with a CFTR corrector, CFTR potentiator, mucolytic, anti-inflammatory agent or a combination thereof are provided as is a method for preventing or treating cystic fibrosis.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 10, 2014
    Applicant: TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguérin, Rudolf Volkmer, Lars Vouilleme
  • Compositions and methods for inhibiting the interaction between CFTR and CAL
    Patent number: 8415292
    Abstract: The present invention features compositions and methods for increasing the cell surface expression of degradation-prone CFTR proteins and preventing or treating cystic fibrosis. The invention provides peptides and peptidomimetics that selectively inhibit the interaction between CAL and mutant CFTR proteins, thereby stabilizing the CFTR and facilitating transport of the same to the cell surface.
    Type: Grant
    Filed: October 20, 2009
    Date of Patent: April 9, 2013
    Assignee: Trustees of Dartmouth College
    Inventors: Dean Madden, Patrick R. Cushing, Prisca Boinguérin, Rudolf Volkmer, Lars Vouilleme
  • Compositions and Methods for Inhibiting the Interaction Between CFTR and CAL
    Publication number: 20120071396
    Abstract: The present invention features compositions and methods for increasing the cell surface expression of degradation-prone CFTR proteins and preventing or treating cystic fibrosis. The invention provides peptides and peptidomimetics that selectively inhibit the interaction between CAL and mutant CFTR proteins, thereby stabilizing the CFTR and facilitating transport of the same to the cell surface.
    Type: Application
    Filed: November 9, 2011
    Publication date: March 22, 2012
    Applicant: Trustees of Dartmouth College
    Inventors: Dean R. Madden, Patrick R. Cushing, Prisca Boisguearin, Rudolph Volkmer, Lars Vouilleme
  • Compositions and Methods for Inhibiting the Interaction between CFTR and CAL
    Publication number: 20110201544
    Abstract: The present invention features compositions and methods for increasing the cell surface expression of degradation-prone CFTR proteins and preventing or treating cystic fibrosis. The invention provides peptides and peptidomimetics that selectively inhibit the interaction between CAL and mutant CFTR proteins, thereby stabilizing the CFTR and facilitating transport of the same to the cell surface.
    Type: Application
    Filed: October 20, 2009
    Publication date: August 18, 2011
    Inventors: Dean Madden, Patrick R. Cushing, Prisca Boisguerin, Rudolf Volkmer, Lars Vouilleme