Abstract: A cleaning method for cleaning a filling machine for filling at least to one side open packs with products is described and illustrated, wherein the filling machine has a transport device for transporting the at least to one side open packs through the filling machine. To ensure satisfactory cleaning results repeatably in a defined and/or shorter time, it is provided that a preceding plurality of at least to one side open packs is transported at least partially through the filling machine by a transport device and is filled with products, at least one nozzle for dispensing cleaning medium is transported at least partially through the filling machine by the transport device and cleaning medium is thereby dispensed for cleaning the filling machine, and after the filling machine has been cleaned, a subsequent plurality of at least to one side open packs is transported at least partially through the filling machine by the transport device and is thereby filled with products.

Abstract: The present invention relates to a method of identifying a subject being susceptible to a cardiac intervention based on the determination of GDF-15 in a sample of a subject in need of a cardiac intervention. Moreover, the present invention pertains to a method for predicting the risk of mortality or a further acute cardiovascular event for a subject suffering from a cardiovascular complication based on the determination of GDF-15 and a natriuretic peptide and/or a cardiac troponin in a sample the said subject. Also encompassed by the present invention are devices and kits for carrying out the aforementioned methods.

Abstract: Described and illustrated is a device for filling and/or processing packagings, in particular composite cardboard packagings, and/or for processing packages, preferably comprising composite cardboard packagings, with a space delimited at least partially by side walls, in particular for receiving a sterile or aseptic atmosphere, with at least one cell carrier for receiving at least one packaging and/or package and with at least one transport device for transporting the packagings and/or packages at least partially and at least in sections through the space. In order to easily and reliably achieve a sterile or aseptic atmosphere in the limited space, it is provided that at least one side wall with a lower edge is immersed in a liquid bath and that the at least one cell carrier is guided beneath the side wall through the liquid bath outwards to the transport device arranged on the side of the side wall immersed in the liquid bath facing away from the space.

Abstract: The present invention relates to a method of identifying a subject being susceptible to a cardiac intervention based on the determination of GDF-15 in a sample of a subject in need of a cardiac intervention. Moreover, the present invention pertains to a method for predicting the risk of mortality or a further acute cardiovascular event for a subject suffering from a cardiovascular complication based on the determination of GDF-15 and a natriuretic peptide and/or a cardiac troponin in a sample the said subject. Also encompassed by the present invention are devices and kits for carrying out the aforementioned methods.

Abstract: The present invention relates to a method of identifying a subject being susceptible to a cardiac intervention based on the determination of GDF-15 in a sample of a subject in need of a cardiac intervention. Moreover, the present invention pertains to a method for predicting the risk of mortality or a further acute cardiovascular event for a subject suffering from a cardiovascular complication based on the determination of GDF-15 and a natriuretic peptide and/or a cardiac troponin in a sample the said subject. Also encompassed by the present invention, are devices and kits for carrying out the aforementioned methods.

Abstract: The present invention relates to a method of identifying a subject being susceptible to a cardiac intervention based on the determination of GDF-15 in a sample of a subject in need of a cardiac intervention. Moreover, the present invention pertains to a method for predicting the risk of mortality or a further acute cardiovascular event for a subject suffering from a cardiovascular complication based on the determination of GDF-15 and a natriuretic peptide and/or a cardiac troponin in a sample the said subject. Also encompassed by the present invention are devices and kits for carrying out the aforementioned methods.

Abstract: The present invention relates to a method of identifying a subject being susceptible to a cardiac intervention based on the determination of GDF-15 in a sample of a subject in need of a cardiac intervention. Moreover, the present invention pertains to a method for predicting the risk of mortality or a further acute cardiovascular event for a subject suffering from a cardiovascular complication based on the determination of GDF-15 and a natriuretic peptide and/or a cardiac troponin in a sample the said subject. Also encompassed by the present invention are devices and kits for carrying out the aforementioned methods.

Abstract: The invention relates to a method for treatment of unstable coronary artery disease, which is characterised by an early revascularisation together with administration of a low molecular weight heparin. Preferably the low molecular weight heparin is administered up to revascularisation. The methods are also useful for treatment of unstable angina and not worsening chest pain and for treatment of non-Q-wave myocardial infarction (mild heart attack).