Abstract: A syringe system for the administration of lyophilized drugs includes a syringe barrel and a stopper and a needled guard each coupled with the syringe barrel. A reconstitution plunger is removably coupled with the stopper. A diluent is withdrawn from the syringe into a vial containing a lyophilized drug, and the diluent and drug are mixed to form a therapeutic agent. The reconstitution plunger is then replaced by an administration plunger. The length of the reconstitution plunger is greater than the length of the administration plunger in order to prevent activation of the needle guard during reconstitution. Alternatively, a single plunger system may be used in which the plunger can transition from an extended length during reconstitution to a shortened length during administration. During administration, a radial element of the plunger contacts latch members of the needle guard, whereupon the shield advances to an extended position covering the needle.

Abstract: A needle guard for a syringe including tabs and preferably springboards disposed on the needle guard configured to engage a luer lock to prevent rotation of the luer lock during needle exchange. The body of the needle guard preferably includes springboards which are in communication with tabs disposed on the shield when the shield is in a first, retracted position. Inward or radial depression of the tabs forces the springboards to contact the luer lock and prevent rotation of the luer lock. The needle guard further comprises a slot disposed near the proximal end of the shield which is configured to engage an end tab disposed near the distal end of the body. When the needle guard is activated, the shield slides to a second, extended position and the end tab enters into the slot to lock the shield in the extended position.

Abstract: A needle guard for a syringe including tabs and preferably springboards disposed on the needle guard configured to engage a luer lock to prevent rotation of the luer lock during needle exchange. The body of the needle guard preferably includes springboards which are in communication with tabs disposed on the shield when the shield is in a first, retracted position. Inward or radial depression of the tabs forces the springboards to contact the luer lock and prevent rotation of the luer lock. The needle guard further comprises a slot disposed near the proximal end of the shield which is configured to engage an end tab disposed near the distal end of the body. When the needle guard is activated, the shield slides to a second, extended position and the end tab enters into the slot to lock the shield in the extended position.

Abstract: The present invention provides an injection device including a syringe having a distal end for receiving a needle, and a plunger inserted into the proximal end. A guard is slidable on the syringe, has a proximal end, a distal end, and is biased from a first position wherein the needle is exposed toward a second position wherein the guard covers the needle. The syringe includes a body having a central cylindrical opening for receiving medicine and the plunger, and further includes a pair of longitudinally extending members on opposite sides of the body. The guard has an interior configuration for mating with the longitudinal members and sliding thereon. The syringe and guard preferably are formed of plastic. The injection device includes cooperating detents for retaining the guard and syringe in the first and second positions. A latch member extends proximally from the guard and is engageable by the plunger as the plunger is depressed to release the first set of cooperating detents.

Abstract: A needle guard for a syringe including tabs and preferably springboards disposed on the needle guard configured to engage a luer lock to prevent rotation of the luer lock during needle exchange. The body of the needle guard preferably includes springboards which are in communication with tabs disposed on the shield when the shield is in a first, retracted position. Inward or radial depression of the tabs forces the springboards to contact the luer lock and prevent rotation of the luer lock. The needle guard further comprises a slot disposed near the proximal end of the shield which is configured to engage an end tab disposed near the distal end of the body. When the needle guard is activated, the shield slides to a second, extended position and the end tab enters into the slot to lock the shield in the extended position.

Abstract: A syringe system for the administration of lyophilized drugs includes a syringe barrel and a stopper and a needled guard each coupled with the syringe barrel. A reconstitution plunger is removably coupled with the stopper. A diluent is withdrawn from the syringe into a vial containing a lyophilized drug, and the diluent and drug are mixed to form a therapeutic agent. The reconstitution plunger is then replaced by an administration plunger. The length of the reconstitution plunger is greater than the length of the administration plunger in order to prevent activation of the needle guard during reconstitution. Alternatively, a single plunger system may be used in which the plunger can transition from an extended length during reconstitution to a shortened length during administration. During administration, a radial element of the plunger contacts latch members of the needle guard, whereupon the shield advances to an extended position covering the needle.

Abstract: A medical injection system includes a needle guard and an automatic injection system. The needle guard has a cartridge housing coupled with a release mechanism and configured to house a medical cartridge having a needle, a plunger and a carrier configured to carry the dose. Coupled with the cartridge housing and the release mechanism is a shield that is extendable between a retracted and an extended position that substantially covers the needle. The release mechanism is engageable and configured to maintain the shield in the retracted position and allow the shield to extend upon engagement. The automatic injection system can be configured to house the needle guard and configured to inject the dose when activated. The automatic injection system has a drive system configured to depress the plunger and engage the release mechanism when the automatic injection system is activated, and an activation system configured to activate the automatic injection system.