Patents by Inventor Lasantha R. Bandara

Lasantha R. Bandara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide antagonists of DP transcription factors
    Patent number: 7160981
    Abstract: The invention provides a polypeptide consisting essentially of a sequence corresponding to residues 163 to 199 of DP-1 as shown in the Figure, and fragments and variants thereof capable of antagonizing the heterodimerization of a DP protein with an E2F protein. Such peptides may be used to induce apoptosis in a cell by introducing into the cell an effective amount of said peptide. Such cells include cardiovascular cells, and the peptide may be delivered in a stent to treat or prevent restinosis.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: January 9, 2007
    Assignee: Prolifix Limited
    Inventors: Nicholas B. La Thangue, Lasantha R. Bandara
  • Peptide antagonists of DP transcription factors
    Publication number: 20020103121
    Abstract: The invention provides a polypeptide consisting essentially of a sequence corresponding to residues 163 to 199 of DP-1 as shown in the Figure, and fragments and variants thereof capable of antagonizing the heterodimerization of a DP protein with an E2F protein. Such peptides may be used to induce apoptosis in a cell by introducing into the cell an effective amount of said peptide. Such cells include cardiovascular cells, and the peptide may be delivered in a stent to treat or prevent restinosis.
    Type: Application
    Filed: July 9, 2001
    Publication date: August 1, 2002
    Applicant: Prolifix Limited
    Inventors: Nicholas B. La Thangue, Lasantha R. Bandara
  • Peptide antagonists of DP transcription factors
    Patent number: 6268334
    Abstract: The invention provides a polypeptide consisting essentially of a sequence corresponding to residues 163 to 199 of DP-1 as shown in the Figure, and fragments and variants thereof capable of antagonising the heterodimerization of a DP protein with an E2F protein. Such peptides may be used to induce apoptosis in a cell by introducing into the cell an effective amount of said peptide. Such cells include cardiovascular cells, and the peptide may be delivered in a stent to treat or prevent restinosis.
    Type: Grant
    Filed: May 27, 1999
    Date of Patent: July 31, 2001
    Assignee: Prolifix Limited
    Inventors: Nicholas B. La Thangue, Lasantha R. Bandara