Patents by Inventor Lasse Ebdrup Pedersen

Lasse Ebdrup Pedersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered mammalian cells for production of recombinant proteins
    Patent number: 10982191
    Abstract: The present invention relates to mammalian cells modified to provide for improved expression of a recombinant protein of interest. In particular, the invention relates to CHO cells and other host cells in which the expression of one or more endogenous secreted proteins has been disrupted, as well as to the preparation, identification and use of such cells in the production of recombinant proteins.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: April 20, 2021
    Assignees: DANMARKS TEKNISKE UNIVERSITET, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Bjørn Gunnar Voldborg, Lasse Ebdrup Pedersen, Bernhard Palsson
  • METHODS FOR DECOUPLING CELL GROWTH FROM PRODUCTION OF BIOCHEMICALS AND RECOMBINANT POLYPEPTIDES
    Publication number: 20190367930
    Abstract: The present invention generally relates to industrial microbiology, and specifically to the production of biochemical compounds, such as L-serine, L-tyrosine, mevalonate and their derivatives, and recombinant polypeptides using genetically modified microorganisms. More particularly, the present invention pertains to the decoupling of cell growth from production of biochemical compounds, such as L-serine, L-tyrosine, mevalonate and their derivatives, in a microorganism by down regulating the nucleotide biosynthesis in said microorganism.
    Type: Application
    Filed: July 28, 2017
    Publication date: December 5, 2019
    Inventors: Songyuan Li, Christian Bille Jendresen, Lasse Ebdrup Pedersen, Jenny Landberg, Kristoffer Bach Falkenberg, Hemanshu Mundhada, Alex Toftgaard Nielsen
  • ENGINEERED MAMMALIAN CELLS FOR PRODUCTION OF RECOMBINANT PROTEINS
    Publication number: 20190136198
    Abstract: The present invention relates to mammalian cells modified to provide for improved expression of a recombinant protein of interest. In particular, the invention relates to CHO cells and other host cells in which the expression of one or more endogenous secreted proteins has been disrupted, as well as to the preparation, identification and use of such cells in the production of recombinant proteins.
    Type: Application
    Filed: April 25, 2017
    Publication date: May 9, 2019
    Applicant: DANMARKS TEKNISKE UNIVERSITET
    Inventors: Bjørn Gunnar Voldborg, Lasse Ebdrup Pedersen