Abstract: An optical assembly including light sources emitting light beams having multiple wavelengths; fiber combiner(s) arranged to combine light beams into combined beam, light beams enter fiber combiner(s); optical homogenizer(s), combined beam having non-homogenous intensity profile received at third end and combined beam having homogeneous intensity profile exits at fourth end; first optical element(s) second optical element(s), between optical homogenizer(s) and light guide(s), first optical element(s) and second optical(s) element collectively steer combined beam towards light guide(s), when optical assembly in use, second optical element(s) is adjustable to steer combined beam; first actuator(s) coupled to first optical element(s); controller coupled to first actuator(s), controller generate first signal controlling first actuator(s) that combined beam is steered by first optical element(s) also causing vibration of first optical element(s) at randomized pattern.

Abstract: Disclosed is an apparatus and method for fluorescence excitation and detection. The apparatus comprises one or more light sources for providing excitation light for fluorescence excitation at an observation spot along an optical axis for excitation, an optical collection element for collecting fluorescence light generated by the excitation light at two or more different observation spots into two or more different measurement channels with an optical axis for collecting non-parallel to the optical axis for excitation of each of the one or more light sources, and, for each of the two or more measurement channels and thereby for each of the two or more observation spots, a dedicated optical detector for detecting fluorescence from the fluorescence light collected by the optical collection element.

Abstract: An apparatus for stacking and coating of very short cavity laser diode arrays. The apparatus includes an array holder fixture to securely hold the very short cavity laser diode arrays and spacer arrays, and a stacking plate. The array holder fixture including a top-side presser to secure a stack of very short cavity laser arrays and spacer arrays from a first end of the stack, a bottom-side presser to secure the stack of very short cavity laser arrays and spacer arrays from a second end of the stack, and a pair of side clamps. The array holder fixture is operatively coupled to the stacking plate during the stacking of the very short cavity laser diode arrays and spacer arrays.

Abstract: An apparatus for stacking and coating of very short cavity laser diode arrays. The apparatus includes an array holder fixture to securely hold the very short cavity laser diode arrays and spacer arrays, and a stacking plate. The array holder fixture including a top-side presser to secure a stack of very short cavity laser arrays and spacer arrays from a first end of the stack, a bottom-side presser to secure the stack of very short cavity laser arrays and spacer arrays from a second end of the stack, and a pair of side clamps. The array holder fixture is operatively coupled to the stacking plate during the stacking of the very short cavity laser diode arrays and spacer arrays.

Abstract: A theranostic laser system for light-activated drug delivery and monitoring. The system includes a light source, a light receiver and a coupler for simultaneously coupling a first optical delivery fiber to the light source for transmitting one or more first downstream light signals from the light source to the first optical delivery fiber and to the light receiver for transmitting one or more first upstream light signals from the first optical delivery fiber to the light receiver.