Patents by Inventor Laszlo S. Bajzar

Laszlo S. Bajzar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for inhibiting the activation of thrombin-activatable fibrinolysis inhibitor (TAFI)
    Patent number: 5993815
    Abstract: Methods and products for the treatment of a disorder characterized by the cleavage of a C-terminal lysine or arginine from an intact peptide are provided. In the methods of the invention a peptide that inhibits the activation of thrombin-activatable fibrinolysis inhibitor (TAFI) is administered in an effective amount and in a pharmaceutically acceptable carrier to a subject having a disorder characterized by the cleavage of a C-terminal lysine or arginine from an intact peptide. The compositions are pharmaceutical compositions of peptides that inhibit the activation of TAFI. Also provided is a monoclonal antibody that binds TAFI zymogen but that does not bind to active TAFI and inhibits the activation of TAFI.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: November 30, 1999
    Assignee: University of Vermont
    Inventors: Laszlo S. Bajzar, Michael E. Nesheim, William R. Church