Patents by Inventor Latha Narayanan

Latha Narayanan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Implantable device for continuous delivery of interferon
    Patent number: 7655254
    Abstract: An implantable device includes a reservoir containing a suspension of an interferon in an amount sufficient to provide continuous delivery of the interferon at a therapeutically effective rate of 1 ng/day to 600 ?g/day to maintain and achieve therapeutic blood or plasma levels of the interferon throughout a substantial period of the administration period.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: February 2, 2010
    Assignee: Intarcia Therapeutics, Inc.
    Inventors: Paula Dennis, Michael A. Desjardin, Stan Lam, Kui Liu, James E. Matsuura, Latha Narayanan, Catherine M. Rohloff, Pauline C. Zamora
  • Complexation of metal ions with polypeptides
    Publication number: 20070015689
    Abstract: Formulations and methods are provided for improving the stability upon exposure to aqueous media of polypeptides present in non-aqueous suspension vehicles. In particular aspects of the invention, formulations are provided that comprise a complex of a metal ion and a polypeptide suspended in a non-aqueous, biocompatible suspension vehicle. Aggregation of individual polypeptide molecules is reduced when aqueous media is introduced to such formulations, serving to stabilize the polypeptide.
    Type: Application
    Filed: June 21, 2006
    Publication date: January 18, 2007
    Applicant: ALZA CORPORATION
    Inventors: Catherine Rohloff, Guohua Chen, Zhongli Ding, Stephen Berry, Latha Narayanan, Michael Desjardin
  • Suspension formulation of interferon
    Publication number: 20060263433
    Abstract: A suspension formulation of interferon includes a non-aqueous, single-phase vehicle including at least one polymer and at least one solvent, the vehicle exhibiting viscous fluid characteristics, and an interferon contained in a particle formulation dispersed in the vehicle. The particle formulation includes a stabilizing component comprising one or more stabilizers selected from the group consisting of carbohydrates, antioxidants, and amino acids. The suspension formulation is characterized in that less than 10% of the interferon degrades over 3 months under an accelerated storage condition.
    Type: Application
    Filed: February 3, 2006
    Publication date: November 23, 2006
    Inventors: Rupal Ayer, Paula Dennis, Michael Desjardin, Stan Lam, Kui Liu, James Matsuura, Latha Narayanan, Catherine Rohloff, Pauline Zamora
  • Implantable device for continuous delivery of interferon
    Publication number: 20060251618
    Abstract: An implantable device includes a reservoir containing a suspension of an interferon in an amount sufficient to provide continuous delivery of the interferon at a therapeutically effective rate of 1 ng/day to 600 ?g/day to maintain and achieve therapeutic blood or plasma levels of the interferon throughout a substantial period of the administration period.
    Type: Application
    Filed: February 3, 2006
    Publication date: November 9, 2006
    Inventors: Paula Dennis, Michael Desjardin, Stan Lam, Kui Liu, James Matsuura, Latha Narayanan, Catherine Rohloff, Pauline Zamora