Abstract: A positive airway pressure therapy management module includes a user interface, a controller and memory. The module may include ports that capture data from a PAP device and/or from sensors. The user interface may display information and questions, and may receive answers. The controller may store data while offline from the network, and may respond to requests over the network while online with the network. A software product includes instructions that, under control of a computer, perform steps for managing positive airway pressure therapy of a patient. A method for managing positive airway pressure therapy of a patient captures data and communicates the data over a network. The method may capture data from a PAP device and/or from sensors, display questions and receiving answers, and calculate indices and/or metrics, perform a pressure titration, and/or relay commands to a PAP device in response to commands from the network.

Abstract: A system and method for controlling and monitoring externally administered breathing air pressure in a series of cycles. During each cycle, the breathing air pressure starts at a base value and is slowly and progressively increased then rapidly reduced to the base value. If the control and monitoring system detects changes consistent with the presence of upper airway obstruction, the values of breathing air pressure for the next cycle are changed to a higher pressure range. A plurality of vital signs may be monitored and included in the breathing air pressure control system. Information obtained during this procedure is subsequently used to determine the most appropriate externally administered breathing airflow pressure for that person.

Abstract: Method and apparatus are provided for carrying out multiple simultaneous transfers of fluid. The method and apparatus are particularly directed toward immunoassays wherein immunologically active compounds, such as antigens and haptens, are detected through their associated antibodies. The device relies on the ability to transfer fluids, such as biological samples and reagents, between a reservoir and an associated receptacle. By providing a receptacle having a port at its lower end and which is otherwise hermetically sealed, such fluid transfer can be effected by immersing the port beneath the surface of the fluid in the reservoir and manipulating the pressure on the remaining surface area outside the port. The transfer of biological fluids at positive pressure provides enhanced fluids flow characteristics, particularly reduction or elimination of the tendency of these fluids to froth or bubble.

Abstract: Method and apparatus are provided for carrying out simultaneous multiple manipulations. The method and apparatus are particularly directed toward heterogeneous (two phases) immunoassays, particularly radioimmunoassay (RIA) and immunoradiometricassays (IRMA and 2-site IRMA). These assays are primarily concerned with the determination of antibodies and immunologically active compounds (antigens and haptens). The device has a plurality of syringes mounted so as to allow for simultaneous and identical movement of the syringe plungers. In addition, means are provided for mounting open tubes, which are employed as solid phase reagents, to the ends of the syringes for the aspiration and discharge of unknown samples, reagents and wash solutions. A reservoir is provided in an upper portion of the apparatus for receiving solutions or dispensing solutions to the syringes. Individual assays may be carried out by using a single syringe and carrying out the process steps by transfers of solutions through a hollow tube.