Abstract: A product carbon footprint (PCF) orchestrator can include a controller configured to generate a PCF determination package, where the PCF determination package includes a data contract and instructions, and where the data contract is configured to receive a plurality of inputs in the form of emission-related data. The controller can also be configured to send the PCF determination package to a customer. The controller can further be configured to obtain PCF results from the customer after the customer uses the data contract following the instructions of the PCF determination package. The controller can also be configured to evaluate the PCF results. Emission data used by the customer to generate the PCF results may not be accessed by the controller.

Abstract: A product carbon footprint (PCF) orchestrator can include a controller configured to generate a PCF determination package, where the PCF determination package includes a data contract and instructions that are customized for a customer system based on query information provided by a customer system, and where the data contract is configured to receive a plurality of inputs in the form of emission-related data. The controller can also be configured to send the PCF determination package to the customer system, where the emissions-related data remains with the customer system when the instructions are followed to generate the PCF results. The controller can further be configured to obtain PCF results and evaluate from the customer system after the customer system uses the data contract following the instructions of the PCF determination package. Emission data used by the customer system to generate the PCF results may not be accessed by the controller.

Abstract: Recombinant microorganisms and methods of using same. The recombinant microorganisms include one or more modifications that reduce the expression and/or activity of a sortase, a sortase-dependent protein, a fibronectin-binding protein, an autolysin, a surface-layer protein, an aggregation-promoting factor, and/or a collagen-binding protein. The modifications can reduce the adhesion characteristics with respect to the non-modified microbes. The recombinant microorganisms can further include a recombinant gene configured to express a biologic. The recombinant microorganisms can be used as delivery vehicles to deliver the biologics to sites such as the gastrointestinal tract.