Patents by Inventor Laura Amori

Laura Amori has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of nicotinic acid N-oxide, their preparation and their use as inhibitors of enzyme 3-hydroxyanthranilate-3, 4-dioxygenase
    Patent number: 9487486
    Abstract: A derivative of nicotinic acid N-oxide is described having formula (I): that acts as inhibitor of enzyme 3-hydroxyanthranilate-3,4-dioxygenase (3HAO), and is thus able to reduce QUIN biosynthesis in vivo under excitotoxic or pathological conditions, said compound being at the same time also chemically stable towards auto-oxidation.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: November 8, 2016
    Assignees: UNIVERSITY OF MARYLAND, BALTIMORE, UNIVERSITA DELGI STUDI DI PARMA
    Inventors: Robert Schwarcz, Gabriele Costantino, Laura Amori
  • DERIVATIVES OF NICOTINIC ACID N-OXIDE, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF ENZYME 3-HYDROXYANTHRANILATE-3, 4-DIOXYGENASE
    Publication number: 20160052886
    Abstract: A derivative of nicotinic acid N-oxide is described having formula (I): that acts as inhibitor of enzyme 3-hydroxyanthranilate-3,4-dioxygenase (3HAO), and is thus able to reduce QUIN biosynthesis in vivo under excitotoxic or pathological conditions, said compound being at the same time also chemically stable towards auto-oxidation.
    Type: Application
    Filed: November 4, 2015
    Publication date: February 25, 2016
    Inventors: ROBERT SCHWARCZ, GABRIELE COSTANTINO, LAURA AMORI
  • Derivatives of nicotinic acid N-oxide, their preparation and their use as inhibitors of enzyme 3-hydroxyanthranilate-3, 4-dioxygenase
    Patent number: 9260394
    Abstract: A derivative of nicotinic acid N-oxide is described having formula (I): that acts as inhibitor of enzyme 3-hydroxyanthranilate-3,4-dioxygenase (3HAO), and is thus able to reduce QUIN biosynthesis in vivo under excitotoxic or pathological conditions, said compound being at the same time also chemically stable towards auto-oxidation.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: February 16, 2016
    Assignees: UNIVERSITY OF MARYLAND, BALTIMORE, UNIVERSITA' DELGI STUDI DI PARMA
    Inventors: Robert Schwarcz, Gabriele Costantino, Laura Amori
  • DERIVATIVES OF NICOTINIC ACID N-OXIDE, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF ENZYME 3-HYDROXYANTHRANILATE-3, 4-DIOXYGENASE
    Publication number: 20130289081
    Abstract: A derivative of nicotinic acid N-oxide is described having formula (I): that acts as inhibitor of enzyme 3-hydroxyanthranilate-3,4-dioxygenase (3HAO), and is thus able to reduce QUIN biosynthesis in vivo under excitotoxic or pathological conditions, said compound being at the same time also chemically stable towards auto-oxidation.
    Type: Application
    Filed: January 19, 2011
    Publication date: October 31, 2013
    Applicants: UNIVERSITA' DEGLI DI PARMA, UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Robert Schwarcz, Gabriele Costantino, Laura Amori