Patents by Inventor Laura Bergonzoni

Laura Bergonzoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Deletion mutant of basic fibroblast growth factor and production thereof
    Patent number: 5352589
    Abstract: The present invention relates to the production, by recombinant DNA techniques, of derivatives of basic fibroblast growth factor (bFGF). These derivatives of bFGF can act as antagonists and/or superagonists of the wild type molecule in the angiogenic process. These derivatives, as well as wild type bFGF, may be prepared by the use of strains or E. coli which have been transformed with plasmids carrying nucleotide sequence coding for human and bovine bFGF and their derivatives.
    Type: Grant
    Filed: June 2, 1993
    Date of Patent: October 4, 1994
    Assignee: Farmitalia Carlo Erba S.R.L.
    Inventors: Laura Bergonzoni, Antonella Isacchi, Paolo Sarmientos, Gilles Cauet
  • Extracellular form of the human fibroblast growth factor receptor
    Patent number: 5288855
    Abstract: The present invention provides a polypeptide which is capable of binding specifically human basic fibroblast growth factor and human acidic fibroblast growth factor, a DNA sequence which encodes the polypeptide of the invention and a vector which incorporates a DNA sequence of the invention and which is capable, when provided in a transformed host, of expressing the polypeptide of the invention encoded by the DNA sequence. A host transformed with such a vector forms part of the invention also.
    Type: Grant
    Filed: December 28, 1992
    Date of Patent: February 22, 1994
    Assignee: Farmitalia Carlo Erba
    Inventors: Laura Bergonzoni, Guy Mazue, Antonella Isacchi, Romeo Roncucci, Paolo Sarmientos