Patents by Inventor Laura Bohn

Laura Bohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11512075
    Abstract: The invention provides 20-nor-salvinorin A, an analog of the kappa-opioid agonist salvinorin A. The 20-nor-salvinorin A is an active kappa-opioid modulator and can be used for treatment of medical conditions wherein modulation of the kappa-opioid receptor is medically indicated, such as pain, pruritis, depression, or inflammation, or conditions implicating perception and consciousness. 20-nor-salvinorin A can be less additive when used in treatment compared to a mu-opioid receptor agonist, and 20-nor-salvinorin A is more stable in vivo than is parent compound salvinorin A. The invention further provides synthetic intermediates and procedures for preparation of 20-nor-salvinorin A.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: November 29, 2022
    Assignee: The Scripps Research Institute
    Inventors: Ryan Shenvi, Jeremy Roach, Yusuke Sasano, Laura Bohn, Cullen Schmid
  • Patent number: 10829453
    Abstract: The present technology is directed to compounds, compositions, and methods related to non-morphinan-like kappa opioid receptor (KOR) antagonists. The technology is suited to treat addiction, diuresis, depression, post traumatic stress disorder, an eating disorder, panic disorder, social anxiety disorder, general anxiety disorder, obsessive compulsive disorders, excessive or unreasonable specific phobias, and/or other conditions related to anxiety or aversion-reward responses.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: November 10, 2020
    Assignees: University of Kansas, THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Jeffrey Aube, Kevin Frankowski, Thomas Prisinzano, Laura Bohn
  • Publication number: 20200131162
    Abstract: The invention provides 20-nor-salvinorin A, an analog of the kappa-opioid agonist salvinorin A. The 20-nor-salvinorin A is an active kappa-opioid modulator and can be used for treatment of medical conditions wherein modulation of the kappa-opioid receptor is medically indicated, such as pain, pruritis, depression, or inflammation, or conditions implicating perception and consciousness. 20-nor-salvinorin A can be less additive when used in treatment compared to a mu-opioid receptor agonist, and 20-nor-salvinorin A is more stable in vivo than is parent compound salvinorin A. The invention further provides synthetic intermediates and procedures for preparation of 20-nor-salvinorin A.
    Type: Application
    Filed: June 7, 2018
    Publication date: April 30, 2020
    Inventors: Ryan Shenvi, Jeremy Roach, Yusuke Sasano, Laura Bohn, Cullen Schmid
  • Publication number: 20190300486
    Abstract: The present technology is directed to compounds, compositions, and methods related to non-morphinan-like kappa opioid receptor (KOR) antagonists. The technology is suited to treat addiction, diuresis, depression, post traumatic stress disorder, an eating disorder, panic disorder, social anxiety disorder, general anxiety disorder, obsessive compulsive disorders, excessive or unreasonable specific phobias, and/or other conditions related to anxiety or aversion-reward responses.
    Type: Application
    Filed: November 2, 2018
    Publication date: October 3, 2019
    Inventors: Jeffrey Aube, Kevin Frankowski, Thomas Prisinzano, Laura Bohn
  • Patent number: 10118896
    Abstract: The present technology is directed to compounds, compositions, and methods related to non-morphinan-like kappa opioid receptor (KOR) antagonists. The technology is suited to treat addiction, diuresis, depression, post traumatic stress disorder, an eating disorder, panic disorder, social anxiety disorder, general anxiety disorder, obsessive compulsive disorders, excessive or unreasonable specific phobias, and/or other conditions related to anxiety or aversion-reward responses.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: November 6, 2018
    Assignees: UNIVERSITY OF KANSAS, THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Jeffrey Aube, Kevin Frankowski, Thomas Prisinzano, Laura Bohn
  • Patent number: 9941507
    Abstract: A method for production of a thin-film battery includes providing a mount structure, applying of a first unmasked flow of a first electrode material to the mount structure in order to form a first electrode layer, applying a second unmasked flow of a battery material in order to form a battery layer, and applying a third unmasked flow of a second electrode material in order to form a second electrode layer. The applying steps are repeated in order to produce a thin-film battery which consists of a plurality of first electrode layers, a plurality of battery layers, and a plurality of second electrode layers.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: April 10, 2018
    Assignee: Robert Bosch GmbH
    Inventors: Tjalf Pirk, Andreas Krauss, Thomas Teuschel, Laura Bohne
  • Publication number: 20170260141
    Abstract: The present technology is directed to compounds, compositions, and methods related to non-morphinan-like kappa opioid receptor (KOR) antagonists. The technology is suited to treat addiction, diuresis, depression, post traumatic stress disorder, an eating disorder, panic disorder, social anxiety disorder, general anxiety disorder, obsessive compulsive disorders, excessive or unreasonable specific phobias, and/or other conditions related to anxiety or aversion-reward responses.
    Type: Application
    Filed: November 25, 2015
    Publication date: September 14, 2017
    Inventors: Jeffrey Aube, Kevin Frankowski, Thomas Prisinzano, Laura Bohn
  • Patent number: 9608307
    Abstract: A semiconductor substrate-based system for an RFID device, in particular an RFID transponder, having a semiconductor substrate and an electronic circuit system which is structured on the semiconductor substrate is provided. The semiconductor substrate-based system also has a thin-layer battery, likewise structured on the semiconductor substrate, for supplying power to the RFID device. Moreover, an RFID device having a corresponding semiconductor substrate-based system, and a method for manufacturing a corresponding semiconductor substrate-based system are provided.
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: March 28, 2017
    Assignee: ROBERT BOSCH GMBH
    Inventors: Tjalf Pirk, Andreas Krauss, Laura Bohne, Janpeter Wolff
  • Patent number: 9540375
    Abstract: The present invention is a selective kappa opioid receptor effector, or a pharmaceutically acceptable salt thereof, useful for treating ethanol use disorder withdrawal, anxiety and/or depression, schizophrenia, mania or post-traumatic stress disorder.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: January 10, 2017
    Assignees: University of Kansas, The Scripps Research Institute
    Inventors: Jeffrey Aube, Laura Bohn, Thomas Edward Prisinzano, Frank John Schoenen, Kevin J. Frankowski
  • Publication number: 20160257685
    Abstract: The present invention is a selective kappa opioid receptor effector, or a pharmaceutically acceptable salt thereof, useful for treating ethanol use disorder withdrawal, anxiety and/or depression, schizophrenia, mania or post-traumatic stress disorder.
    Type: Application
    Filed: May 17, 2016
    Publication date: September 8, 2016
    Inventors: Jeffrey Aube, Laura Bohn, Thomas Edward Prisinzano, Frank John Schoenen, Kevin J. Frankowski
  • Patent number: 9345703
    Abstract: The present invention is a selective kappa opioid receptor effector, or a pharmaceutically acceptable salt thereof, useful for treating ethanol use disorder withdrawal, anxiety and/or depression, schizophrenia, mania or post-traumatic stress disorder.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: May 24, 2016
    Assignees: University of Kansas, The Scripps Research Institute
    Inventors: Jeffrey Aube, Laura Bohn, Thomas Edward Prisinzano, Frank John Schoenen, Kevin John Frankowski
  • Publication number: 20140371227
    Abstract: The present invention is a selective kappa opioid receptor effector, or a pharmaceutically acceptable salt thereof, useful for treating ethanol use disorder withdrawal, anxiety and/or depression, schizophrenia, mania or post-traumatic stress disorder.
    Type: Application
    Filed: September 14, 2012
    Publication date: December 18, 2014
    Applicants: The Scripps Research Institute, University of Kansas
    Inventors: Jeffrey Aube, Laura Bohn, Thomas Edward Prisinzano, Frank John Schoenen, Kevin John Frankowski
  • Publication number: 20110294015
    Abstract: A method for production of a thin-film battery includes providing a mount structure, applying of a first unmasked flow of a first electrode material to the mount structure in order to form a first electrode layer, applying a second unmasked flow of a battery material in order to form a battery layer, and applying a third unmasked flow of a second electrode material in order to form a second electrode layer. The applying steps are repeated in order to produce a thin-film battery which consists of a plurality of first electrode layers, a plurality of battery layers, and a plurality of second electrode layers.
    Type: Application
    Filed: May 24, 2011
    Publication date: December 1, 2011
    Applicant: Robert Bosch GmbH
    Inventors: Tjalf Pirk, Andreas Krauss, Thomas Teuschel, Laura Bohne
  • Publication number: 20110278363
    Abstract: A semiconductor substrate-based system for an RFID device, in particular an RFID transponder, having a semiconductor substrate and an electronic circuit system which is mounted on the semiconductor substrate is provided. The semiconductor substrate-based system also has a thin-layer battery, likewise mounted on the semiconductor substrate, for supplying power to the RFID device. Moreover, an RFID device having a corresponding semiconductor substrate-based system, and a method for manufacturing a corresponding semiconductor substrate-based system are provided.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 17, 2011
    Inventors: Tjalf Pirk, Andreas Krauss, Laura Bohne, Janpeter Wolff