Patents by Inventor Laura Bortolin

Laura Bortolin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8722347
    Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: May 13, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Todd H. Rider, Laura Bortolin
  • Patent number: 8053744
    Abstract: A method for using information encrypted with a nucleic acid molecule to backtrack an item's path or identify a point of origin. Unique nucleic acid-containing tags are seeded at one or more geographic locations. Using sequence analysis techniques, the person or object of interest is examined for the presence of one or more of the seeded nucleic acids. The geographic location associated with each detected nucleic acid is used to backtrack the item's path or extrapolate a probable point of origin.
    Type: Grant
    Filed: April 13, 2009
    Date of Patent: November 8, 2011
    Assignee: SRC, Inc.
    Inventor: Laura Bortolin
  • Publication number: 20100258743
    Abstract: A method for using information encrypted with a nucleic acid molecule to backtrack an item's path or identify a point of origin. Unique nucleic acid-containing tags are seeded at one or more geographic locations. Using sequence analysis techniques, the person or object of interest is examined for the presence of one or more of the seeded nucleic acids. The geographic location associated with each detected nucleic acid is used to backtrack the item's path or extrapolate a probable point of origin.
    Type: Application
    Filed: April 13, 2009
    Publication date: October 14, 2010
    Applicant: SRC, INC.
    Inventor: Laura Bortolin
  • Publication number: 20100003700
    Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.
    Type: Application
    Filed: February 27, 2009
    Publication date: January 7, 2010
    Applicant: Massachusetts Institute of Technology
    Inventors: Todd H. Rider, Laura Bortolin
  • Patent number: 7517660
    Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: April 14, 2009
    Assignee: Massachusetts Institute of Technology
    Inventors: Todd H. Rider, Laura Bortolin
  • Publication number: 20070087391
    Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.
    Type: Application
    Filed: June 19, 2006
    Publication date: April 19, 2007
    Inventors: Todd Rider, Laura Bortolin
  • Patent number: 7090988
    Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.
    Type: Grant
    Filed: August 3, 2004
    Date of Patent: August 15, 2006
    Assignee: Massachusetts Institute of Technology
    Inventors: Todd H. Rider, Laura Bortolin
  • Publication number: 20060160148
    Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.
    Type: Application
    Filed: August 3, 2004
    Publication date: July 20, 2006
    Applicant: Massachusetts Institute of Technology
    Inventors: Todd Rider, Laura Bortolin
  • Publication number: 20050277204
    Abstract: The present invention provides improved devices for separating and/or detecting targets from biological, environmental, or chemical samples.
    Type: Application
    Filed: February 11, 2005
    Publication date: December 15, 2005
    Applicant: Massachusetts Institute of Technology
    Inventors: Mark Hollis, Nicholas Freeland Judson, Christina Rudzinski, Lalitha Parameswaran, Theodore Fedynyshyn, Catherine Cabrera, Laura Bortolin, Robert King, Matthew Angel
  • Publication number: 20050118570
    Abstract: The present invention provides improved methods, compositions, and devices for separating and/or detecting targets from biological, environmental, or chemical samples.
    Type: Application
    Filed: August 12, 2004
    Publication date: June 2, 2005
    Applicant: Massachusetts Institute of Technology
    Inventors: Mark Hollis, Nicholas Freeland Judson, Christina Rudzinski, Lalitha Parameswaran, Theodore Fedynyshyn, Catherine Cabrera, Laura Bortolin