Patents by Inventor Laura Bortolin
Laura Bortolin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8722347Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.Type: GrantFiled: February 27, 2009Date of Patent: May 13, 2014Assignee: Massachusetts Institute of TechnologyInventors: Todd H. Rider, Laura Bortolin
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Patent number: 8053744Abstract: A method for using information encrypted with a nucleic acid molecule to backtrack an item's path or identify a point of origin. Unique nucleic acid-containing tags are seeded at one or more geographic locations. Using sequence analysis techniques, the person or object of interest is examined for the presence of one or more of the seeded nucleic acids. The geographic location associated with each detected nucleic acid is used to backtrack the item's path or extrapolate a probable point of origin.Type: GrantFiled: April 13, 2009Date of Patent: November 8, 2011Assignee: SRC, Inc.Inventor: Laura Bortolin
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Publication number: 20100258743Abstract: A method for using information encrypted with a nucleic acid molecule to backtrack an item's path or identify a point of origin. Unique nucleic acid-containing tags are seeded at one or more geographic locations. Using sequence analysis techniques, the person or object of interest is examined for the presence of one or more of the seeded nucleic acids. The geographic location associated with each detected nucleic acid is used to backtrack the item's path or extrapolate a probable point of origin.Type: ApplicationFiled: April 13, 2009Publication date: October 14, 2010Applicant: SRC, INC.Inventor: Laura Bortolin
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Publication number: 20100003700Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.Type: ApplicationFiled: February 27, 2009Publication date: January 7, 2010Applicant: Massachusetts Institute of TechnologyInventors: Todd H. Rider, Laura Bortolin
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Patent number: 7517660Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.Type: GrantFiled: June 19, 2006Date of Patent: April 14, 2009Assignee: Massachusetts Institute of TechnologyInventors: Todd H. Rider, Laura Bortolin
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Publication number: 20070087391Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.Type: ApplicationFiled: June 19, 2006Publication date: April 19, 2007Inventors: Todd Rider, Laura Bortolin
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Patent number: 7090988Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.Type: GrantFiled: August 3, 2004Date of Patent: August 15, 2006Assignee: Massachusetts Institute of TechnologyInventors: Todd H. Rider, Laura Bortolin
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Publication number: 20060160148Abstract: A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where binding of the antigen to the antibodies results in an increase in calcium concentration in the cytosol of the cell, the cell further having a emitter molecule which, in response to the increased calcium concentration in the cytosol, emits a photon; (2) a liquid medium for receiving the antigen and in which the cell is immersed; and (3) an optical detector arranged for receiving the photon emitted from the cell.Type: ApplicationFiled: August 3, 2004Publication date: July 20, 2006Applicant: Massachusetts Institute of TechnologyInventors: Todd Rider, Laura Bortolin
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Publication number: 20050277204Abstract: The present invention provides improved devices for separating and/or detecting targets from biological, environmental, or chemical samples.Type: ApplicationFiled: February 11, 2005Publication date: December 15, 2005Applicant: Massachusetts Institute of TechnologyInventors: Mark Hollis, Nicholas Freeland Judson, Christina Rudzinski, Lalitha Parameswaran, Theodore Fedynyshyn, Catherine Cabrera, Laura Bortolin, Robert King, Matthew Angel
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Publication number: 20050118570Abstract: The present invention provides improved methods, compositions, and devices for separating and/or detecting targets from biological, environmental, or chemical samples.Type: ApplicationFiled: August 12, 2004Publication date: June 2, 2005Applicant: Massachusetts Institute of TechnologyInventors: Mark Hollis, Nicholas Freeland Judson, Christina Rudzinski, Lalitha Parameswaran, Theodore Fedynyshyn, Catherine Cabrera, Laura Bortolin