Patents by Inventor Laura CALZA

Laura CALZA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electrospun fibers for a local release of an anti-inflammatory drug and a promyelinating drug
    Patent number: 11992560
    Abstract: The present invention relates to electro spun fibers for a local release in the central nervous system of an anti-inflammatory and a promyelinating agent over a defined time-window, in order to limit secondary neurodegeneration triggered by the glutamate release and supported by on-going inflammation. The combined treatment aimed to reduce inflammation and improve remyelination in the very early stage of the pathology improving the chronic clinical outcome of the lesion. In particular the present invention relates to electrospun polymeric fibers, wherein said fibers are loaded with 3,3,5-Triiodo-L-thyronine (T3) and Ibuprofen.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: May 28, 2024
    Assignee: ALMA MATER STUDIORUM—UNIVERSITÀ DI BOLOGNA
    Inventors: Laura Calza, Luciana Giardino, Maria Letizia Focarete, Chiara Gualandi, Maria-Laura Bolognesi, Nadia Passerini, Giampiero Pagliuca, Teresa Gazzotti, Elisa Zironi
  • AGENT FOR TREATMENT OF DERMATOLOGICAL DISORDERS
    Publication number: 20220064243
    Abstract: The present invention provides a non-natural polypeptide for the treatment or prevention of skin disorders in a mammal. Administration of the polypeptide is well tolerated by the mammal. The non-natural polypeptide is provided at high purity.
    Type: Application
    Filed: September 17, 2019
    Publication date: March 3, 2022
    Inventors: Gino VILLETTI, Bruno Pietro IMBIMBO, Laura CALZÀ
  • ELECTROSPUN FIBERS FOR A LOCAL RELEASE OF AN ANTI-INFLAMMATORY DRUG AND A PROMYELINATING DRUG
    Publication number: 20210244677
    Abstract: The present invention relates to electro spun fibers for a local release in the central nervous system of an anti-inflammatory and a promyelinating agent over a defined time-window, in order to limit secondary neurodegeneration triggered by the glutamate release and supported by on-going inflammation. The combined treatment aimed to reduce inflammation and improve remyelination in the very early stage of the pathology improving the chronic clinical outcome of the lesion. In particular the present invention relates to electrospunpolymeric fibers, wherein said fibers are loaded with 3,3,5-Triiodo-L-thyronine (T3) and Ibuprofen.
    Type: Application
    Filed: June 14, 2018
    Publication date: August 12, 2021
    Applicant: ALMA MATER STUDIORUM - UNIVERSITÀ DI BOLOGNA
    Inventors: Laura CALZA, Luciana GIARDINO, Maria Letizia FOCARETE, Chiara GUALANDI, Maria-Laura BOLOGNESI, Nadia PASSERINI, Giampiero PAGLIUCA, Teresa GAZZOTTI, Elisa ZIRONI
  • 1-(2-FLUOROBIPHENYL-4-YL)-CYCLOPROPANECARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DOWN'S SYNDROME
    Publication number: 20150335596
    Abstract: Derivatives of 1-(2-fluorobiphenyl-4-yl)-cyclopropanecarboxylic acid are useful for improving the cognitive capacity of patients with intellectual disabilities, an IQ of less than 85, diagnosed with mental retardation, and, most specifically, those with Down's syndrome.
    Type: Application
    Filed: May 22, 2015
    Publication date: November 26, 2015
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Bruno Pietro IMBIMBO, Laura CALZÀ, Luciana Giardino