Abstract: Methods and systems for coupling a tube set to an endoscope. An illustrative adaptor for coupling a tube set to an endoscope may include a planar head portion having at least one aperture, at least one floating cylinder extending from a proximal end at least partially disposed within the at least one aperture of the planar head portion to a distal tip and having a first lumen extending therethrough, at least one O-ring positioned at the distal tip of the at least one floating cylinder, and at least one biasing element disposed about an outer surface of the at least one floating cylinder and extending from a first end adjacent the at least one aperture of the planar head portion to a second end proximal to the distal tip of the at least one floating cylinder.

Abstract: Methods and systems for refilling a container during an endoscopic procedure. An illustrative container may comprise a container configured to contain a fluid, a water supply tube including a first end, a second end, and a first lumen extending therethrough and in fluid communication with the bottom portion of the container, a gas supply tube including a first end, a second end, and a second lumen extending therethrough and in operative fluid communication with container, a manifold configured to couple the water supply tube and the gas supply tube to the container and including a first end positioned interior to the container and a second end positioned exterior to the container, and a port positioned adjacent to the top portion of the container. The port may be configured to be in selective fluid communication with an interior of the container.

Abstract: A system for controlling the flow of fluid through a medical device may include a medical device having a lumen that extends to a distal end of the medical device; a fluid source configured to supply fluid having a positive pressure to the lumen of the medical device; and a flow controller configured to apply a negative pressure to the fluid within the lumen, wherein the flow controller is triggered to apply the negative pressure upon a lowering of the positive pressure from the fluid source.

Abstract: A system for controlling the flow of fluid through a medical device may include a medical device having a lumen that extends to a distal end of the medical device; a fluid source configured to supply fluid having a positive pressure to the lumen of the medical device; and a flow controller configured to apply a negative pressure to the fluid within the lumen, wherein the flow controller is triggered to apply the negative pressure upon a lowering of the positive pressure from the fluid source.

Abstract: An implantable medical device may comprise an elongated tubular body having a scaffolding forming a plurality of cells. A polymeric covering may be disposed over at least a portion of the stent. The covering may include a plurality of voids formed in an outer surface thereof. An extracellular matrix material coating may be disposed over the polymeric covering and within the plurality of voids.

Abstract: An implantable medical device may comprise an elongated tubular body having a scaffolding forming a plurality of cells. A polymeric covering may be disposed over at least a portion of the stent. The covering may include a plurality of voids formed in an outer surface thereof. An extracellular matrix material coating may be disposed over the polymeric covering and within the plurality of voids.

Abstract: A stent system may include a stent including a first leg having a first end fixedly attached to the distal end of a main body portion and extending distally from the distal end of the main body portion in a deployed configuration, and a second leg having a first end fixedly attached to the distal end of the main body portion and extending distally from the distal end of the main body portion in the deployed configuration. The second leg may extend proximally from the distal end of the main body portion in a delivery configuration. A stent system may include a bifurcated delivery sheath and two guidewires for delivery of two stents at the same time. A method of treating a body lumen may include delivering a contrast fluid including an anti-gas agent while implanting a stent in the body lumen.

Abstract: A system for measuring a pressure in a vein includes a needle sized and shaped to be inserted through a working channel of an endoscope. The needle is extending longitudinally and including a channel extending longitudinally therethrough. The system also includes a pressure sensing device including a longitudinally extending body sized and shaped to be slidably inserted through the channel of the needle and a sensor mounted on a distal portion of the body and connected to a proximal portion of the pressure sensing device via a connection cable. The sensor is configured to detect information corresponding to a pressure of a flow of blood through a vein.

Abstract: A system for measuring a pressure in a vein includes a needle sized and shaped to be inserted through a working channel of an endoscope. The needle is extending longitudinally and including a channel extending longitudinally therethrough. The system also includes a pressure sensing device including a longitudinally extending body sized and shaped to be slidably inserted through the channel of the needle and a sensor mounted on a distal portion of the body and connected to a proximal portion of the pressure sensing device via a connection cable. The sensor is configured to detect information corresponding to a pressure of a flow of blood through a vein.

Abstract: An implantable medical device may comprise an elongated tubular body having a scaffolding forming a plurality of cells. A polymeric covering may be disposed over at least a portion of the stent. The covering may include a plurality of voids formed in an outer surface thereof. An extracellular matrix material coating may be disposed over the polymeric covering and within the plurality of voids.

Abstract: The present disclosure is directed to a delivery catheter with a mechanism of discharging an adhesive during and/or immediately prior to deployment of the medical device by the delivery catheter.

Abstract: A system for controlling the flow of fluid through a medical device may include a medical device having a lumen that extends to a distal end of the medical device; a fluid source configured to supply fluid having a positive pressure to the lumen of the medical device; and a flow controller configured to apply a negative pressure to the fluid within the lumen, wherein the flow controller is triggered to apply the negative pressure upon a lowering of the positive pressure from the fluid source.

Abstract: Apparatuses for manipulating a collapsible medical device include a sheath, a first shaft including a first grasping member and a second grasping member. The second grasping member is separated from the first grasping member by a distance. The collapsible medical device may be manipulated by actuating the first grasping member and the second grasping member and by increasing the distance between the first grasping member and the second grasping member. Methods of using the apparatuses are provided.

Abstract: A system for inserting an element into a target tissue includes an endoscope comprising a working channel extending therethrough and an end cap comprising a cavity extending therein from an open proximal end sized to receive a distal end of the endoscope therein and a closed distal end. The cavity is open to an exterior of the end cap via a window extending laterally through a side wall thereof so that a target tissue may be received within the cavity via the window. The system also comprises a needle sized to be passed through the working channel of the endoscope so that a distal end of the needle is insertable into the cavity thereby, the needle extending longitudinally from a proximal end to a distal end and comprising a lumen for housing an element to be delivered to the target tissue.

Abstract: Embodiments of the disclosure relate to devices, systems and methods of use and manufacture. One such device is a stent. The stent includes a stent body and a coating over at least a portion of the stent body. The coating includes a shape memory polymer having an outer surface. The outer surface defines a first configuration and a second configuration. In the first configuration the outer surface is smooth. In the second configuration, the outer surface includes a micro pattern.

Abstract: The present disclosure is directed to a delivery catheter with a mechanism of discharging an adhesive during and/or immediately prior to deployment of the medical device by the delivery catheter.

Abstract: Apparatuses for manipulating a collapsible medical device include a sheath, a first shaft including a first grasping member and a second grasping member. The second grasping member is separated from the first grasping member by a distance. The collapsible medical device may be manipulated by actuating the first grasping member and the second grasping member and by increasing the distance between the first grasping member and the second grasping member. Methods of using the apparatuses are provided.