Patents by Inventor Laura Fantappie'

Laura Fantappie' has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTI-ANTIGEN BACTERIAL OUTER MEMBRANE VESICLE AND USE THEREOF
    Publication number: 20230390374
    Abstract: There is disclosed a method for the co-expression of multi-antigens in bacterial outer membrane vesicles, immunogenic compositions containing the isolated vesicles and the use thereof for the prevention or treatment of bacterial infections.
    Type: Application
    Filed: October 19, 2021
    Publication date: December 7, 2023
    Applicant: BIOMVIS SRL
    Inventors: Assunta Gagliardi, Alberto Grandi, Laura Fantappie'
  • METHOD FOR THE PRODUCTION OF OUTER MEMBRANE VESICLES AND IMMUNOGENIC COMPOSITIONS THEREOF
    Publication number: 20220175903
    Abstract: The invention relates to gram-negative bacteria carrying gene-inactivating mutations that cause deletion of proteins belonging to the OMV proteome, to Outer Membrane Vesicles (OMVs) produced by these bacteria and immunogenic compositions thereof.
    Type: Application
    Filed: April 16, 2020
    Publication date: June 9, 2022
    Applicant: BIOMVIS S.R.L.
    Inventors: Guido Grandi, Alberto Grandi, Laura Fantappie', Ilaria Zanella, Enrico Koenig, Assunta Gagliardi
  • Immunogenic compositions containing bacterial outer membrane vesicles and therapeutic uses thereof
    Patent number: 11066453
    Abstract: The present invention provides means and products for the stimulation of an immune response against tumors in a subject in need thereof. More specifically the invention provides immunogenic compositions containing bacterial outer membrane vesicles loaded with tumor antigens, fusion proteins comprising a bacterial protein and a tumor antigen, and isolated bacterial outer membrane vesicles (OMVs) containing said fusion proteins. The fusion proteins, OMVs and immunogenic compositions according to the invention are used in the prevention and treatment of tumors.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: July 20, 2021
    Assignee: BIOMVIS SRL
    Inventors: Guido Grandi, Valeria Cafardi, Laura Fantappie′, Renata Grifantini, Alberto Grandi
  • Immunogenic compositions containing bacterial outer membrane vesicles
    Patent number: 11027004
    Abstract: This invention relates to outer membrane vesicles (OMVs) from Gram-negative bacteria. The vesicles comprise heterologous proteins or immunogenic fragments thereof expressed as lipoproteins in their membrane. The OMVs of the invention are capable of eliciting an immune response to the heterologous protein or to a fragment thereof when administered to a mammal. Other aspects of the invention relate to methods of preparing the OMVs and immunogenic compositions containing the same.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: June 8, 2021
    Assignee: BIOMVIS SRL
    Inventors: Guido Grandi, Laura Fantappie', Carmela Irene
  • IMMUNOGENIC COMPOSITIONS CONTAINING BACTERIAL OUTER MEMBRANE VESICLES AND THERAPEUTIC USES THEREOF
    Publication number: 20180353587
    Abstract: The present invention provides means and products for the stimulation of an immune response against tumors in a subject in need thereof. More specifically the invention provides immunogenic compositions containing bacterial outer membrane vesicles loaded with tumor antigens, fusion proteins comprising a bacterial protein and a tumor antigen, and isolated bacterial outer membrane vesicles (OMVs) containing said fusion proteins. The fusion proteins, OMVs and immunogenic compositions according to the invention are used in the prevention and treatment of tumors.
    Type: Application
    Filed: May 17, 2016
    Publication date: December 13, 2018
    Applicant: UNIVERSITA' DEGLI STUDI DI TRENTO
    Inventors: Guido Grandi, Valeria Cafardi, Laura Fantappie', Renata Grifantini, Alberto Grandi
  • IMMUNOGENIC COMPOSITIONS CONTAINING BACTERIAL OUTER MEMBRANE VESICLES
    Publication number: 20180207255
    Abstract: This invention relates to outer membrane vesicles (OMVs) from Gram-negative bacteria. The vesicles comprise heterologous proteins or immunogenic fragments thereof expressed as lipoproteins in their membrane. The OMVs of the invention are capable of eliciting an immune response to the heterologous protein or to a fragment thereof when administered to a mammal. Other aspects of the invention relate to methods of preparing the OMVs and immunogenic compositions containing the same.
    Type: Application
    Filed: October 23, 2017
    Publication date: July 26, 2018
    Applicant: UNIVERSITA' DEGLI STUDI DI TRENTO
    Inventors: Guido Grandi, Laura Fantappie', Carmela Irene