Abstract: A MRS (magnetic resonance spectroscopy or nuclear magnetic resonance NMR)-based PTSD (post-traumatic stress disorder) and mTBI (mild traumatic brain injury) diagnostic system and method uses MRS signals, already pre-processed by the MRS scanner software. The signals are collected in vivo from specific regions of the brain. A wavelet decomposition is applied to the MRS signals, and the amplitude of the wavelet coefficients and their location in the MRS signals are used as features for training diagnostic classifiers of disease states. These classifiers are identified through analysis of features of individuals whose health status is known. Once the classifiers are trained, patients can be diagnosed by using the same wavelet features extracted from in vivo MRS scans of their brain regions.

Abstract: A method and a system for analysis of raw MRS data, in the form of signal strength versus chemical shift (ppm), from multiple scanners, includes “signal estimation” from each raw data set, followed by cross-scanner “data harmonization” of results. The final resulting MRS signals are consistent from one scanner to another, and are used for analysis by radiologists and other physicians.

Abstract: A method and a system for analysis of raw MRS data, in the form of signal strength versus chemical shift (ppm), from multiple scanners, includes “signal estimation” from each raw data set, followed by cross-scanner “data harmonization” of results. The final resulting MRS signals are consistent from one scanner to another, and are used for analysis by radiologists and other physicians.

Abstract: A 2-D MRS (magnetic resonance spectroscopy), or equivalently, NMR (nuclear magnetic resonance), pre-processing method produces clean MRS signals from raw data for possible use, among other applications, for diagnoses of neurological disorders such as PTSD and mTBI of the brain. The specific 2-D MRS data referred to in this invention are the 2-D MRS Correlation Spectroscopy or 2-D COSY data.

Abstract: A MRS (magnetic resonance spectroscopy or nuclear magnetic resonance NMR)-based PTSD (post-traumatic stress disorder) and mTBI (mild traumatic brain injury) diagnostic system and method uses MRS signals, already pre-processed by the MRS scanner software. The signals are collected in vivo from specific regions of the brain. A wavelet decomposition is applied to the MRS signals, and the amplitude of the wavelet coefficients and their location in the MRS signals are used as features for training diagnostic classifiers of disease states. These classifiers are identified through analysis of features of individuals whose health status is known. Once the classifiers are trained, patients can be diagnosed by using the same wavelet features extracted from in vivo MRS scans of their brain regions.

Abstract: Existing approaches for deception detection are primarily based on polygraph systems that measure specific channels of physiology in highly structured interviews and that are interpreted by trained polygraph examiners. Existing approaches for predicting interviewer accuracy involve interviewers' own estimates of their performances which inevitably are biased. The methods and systems described herein provides objective, quantitative and automated metrics to detect deception and predict interviewer accuracy. Physiological information of the interviewer during the interview is recorded by at least a first sensor. The physiological information includes a time series of physiological data. An interview assessment is calculated by a computer. By processing the recorded physiological information, the interview assessment indicates at least one of whether a statement made by the interviewee is likely to be deceitful and whether the interviewer is likely to be accurate in estimating truthfulness of the interviewee.

Abstract: Existing approaches for deception detection are primarily based on polygraph systems that measure specific channels of physiology in highly structured interviews and that are interpreted by trained polygraph examiners. Existing approaches for predicting interviewer accuracy involve interviewers' own estimates of their performances which inevitably are biased. The methods and systems described herein provides objective, quantitative and automated metrics to detect deception and predict interviewer accuracy. Physiological information of the interviewer during the interview is recorded by at least a first sensor. The physiological information includes a time series of physiological data. An interview assessment is calculated by a computer. By processing the recorded physiological information, the interview assessment indicates at least one of whether a statement made by the interviewee is likely to be deceitful and whether the interviewer is likely to be accurate in estimating truthfulness of the interviewee.