Patents by Inventor Laura Knight

Laura Knight has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190127805
    Abstract: A molecular subgroup of cancer is characterised by misregulation of the MAPK signalling pathway and the epithelial-mesenchymal transition (EMT) pathway. Biomarker signatures can be used to identify cancers within the molecular subgroup. The signatures are also useful for identifying the treatment that is best suited for a given patient. A method for selecting a treatment for a subject having a cancer, comprises measuring the expression level(s) of at least biomarker selected from Table A or Table B in a sample from the subject. By assessing the expression level(s) of the at least 1 biomarker it can be determined whether the sample from the subject is positive or negative for a biomarker signature comprising the at least 1 biomarker. Based on the outcome of this assessment different treatments selected from MAPK pathway 10 inhibitors, EMT pathway inhibitors, SRC pathway inhibitors, taxanes and anti-angiogenic therapeutic agents may be indicated. Related treatment methods and products are also provided.
    Type: Application
    Filed: March 13, 2017
    Publication date: May 2, 2019
    Inventors: Aya EL-HELALI, Niamh MCGIVERN, Andrena MCCAVIGAN, Bethanie PRICE, Laura KNIGHT, Nuala MCCABE, Richard KENNEDY, Paul HARKIN, Charlie GOURLEY
  • Publication number: 20090163630
    Abstract: A solid filler composition suitable for applying directly to a substrate comprising i) binder polymer ii) fatty acid salt of linear chain length of from 12 to 26 carbon atoms iii) pigment said composition capable of being formed into a self-supporting, dimensionally stable filler body.
    Type: Application
    Filed: March 15, 2007
    Publication date: June 25, 2009
    Inventors: Gary Jefferson, Laura Knight