Patents by Inventor Laura LOVELOCK

Laura LOVELOCK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of activated clostridial neurotoxins
    Patent number: 11453903
    Abstract: Method of producing an activated clostridial neurotoxin. Composition comprising an activated clostridial neurotoxin. Method of treatment using a composition comprising an activated clostridial neurotoxin.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: September 27, 2022
    Assignee: IPSEN BIOPHARM LIMITED
    Inventors: Laura Lovelock, Daniel Kwan, Peter Daniel Horrocks, Malgorzata Field, Philip Marks
  • Clostridial Neurotoxins Comprising an Exogenous Activation Loop
    Publication number: 20220211823
    Abstract: An engineered clostridial neurotoxin comprising an activation loop that comprises an amino acid sequence of the formula Cys-(Xaa)a-Ile-Asp/Glu-Gly-Arg-(Yaa)b-Cys, wherein a is an integer from 1 to 10, b is an integer from 4 to 15, each iteration of Xaa and Yaa individually represents an amino acid, and the engineered clostridial neurotoxin is not BoNT/C1, a method for producing the same, a method of treating a disease or condition comprising administering the engineered clostridial neurotoxin or the corresponding di-chain clostridial neurotoxin, a composition comprising the engineered clostridial neurotoxin or the corresponding di-chain clostridial neurotoxin, and a polynucleotide encoding the engineered clostridial neurotoxin.
    Type: Application
    Filed: September 27, 2019
    Publication date: July 7, 2022
    Inventors: Adam KUPINSKI, Laura LOVELOCK
  • PRODUCTION OF ACTIVATED CLOSTRIDIAL NEUROTOXINS
    Publication number: 20190161783
    Abstract: The present invention relates to a method of producing activated clostridial neurotoxins that are essentially free of unactivated products, to compositions comprising such and to their use in therapy.
    Type: Application
    Filed: June 30, 2017
    Publication date: May 30, 2019
    Applicant: Ipsen Biopharm Limited
    Inventors: Laura LOVELOCK, Daniel KWAN, Peter Daniel HORROCKS, Malgorzata FIELD, Philip MARKS