Patents by Inventor Laura M. Currie

Laura M. Currie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prolonged preservation of blood platelets
    Patent number: 6221669
    Abstract: This invention provides a method for prolonging the preservation of human blood platelets at reduced temperatures. The method uses an inhibitor system that enables blood platelets to retain their functional integrity during storage. In addition, the inhibitor system prevents the generation of cytokines in the platelet preparation during storage at both 22° C. and 4° C. This is accomplished by interrupting normal platelet function during storage, so as to help keep platelets from activating and losing their shape. Before using the platelets in a transfusion, they are returned to their normal functional level by washing the inhibitor system away from the platelets.
    Type: Grant
    Filed: February 13, 1996
    Date of Patent: April 24, 2001
    Assignee: LifeCell Corporation
    Inventors: Stephen A. Livesey, Jerome Connor, Laura M. Currie
  • Composition comprising three platelet lesion inhibitors for platelet storage
    Patent number: 5919614
    Abstract: This invention provides a method for prolonging the preservation of human blood platelets at reduced temperatures. The method uses an inhibitor system that enables blood platelets to maintain their discoid shape and retain their functional integrity during storage. This is accomplished by interrupting normal platelet function during storage, so as to help keep platelets from activating and losing their shape. Before using the platelets in a transfusion, they are returned to their normal functional level by washing the inhibitor system away from the platelets. In particular, compositions comprising amiloride, adenosine and sodium nitroprusside are disclosed.
    Type: Grant
    Filed: May 8, 1997
    Date of Patent: July 6, 1999
    Assignee: LifeCell Corporation
    Inventors: Stephen A. Livesey, Jerome Connor, Laura M. Currie
  • Prolonged preservation of blood platelets
    Patent number: 5622867
    Abstract: This invention provides a method for prolonging the preservation of human blood platelets at reduced temperatures. The method uses an inhibitor system that enables blood platelets to maintain their discoid shape and retain their functional integrity during storage. This is accomplished by interrupting normal platelet function during storage, so as to help keep platelets from activating and losing their shape. Before using the platelets in a transfusion, they are returned to their normal functional level by washing the inhibitor system away from the platelets.
    Type: Grant
    Filed: October 19, 1994
    Date of Patent: April 22, 1997
    Assignee: Lifecell Corporation
    Inventors: Stephen A. Livesey, Jerome Connor, Laura M. Currie