Patents by Inventor Laura Moschcovich

Laura Moschcovich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Long-acting coagulation factors and methods of producing same
    Patent number: 11976106
    Abstract: Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotropin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions and pharmaceutical formulations comprising the polypeptides and polynucleotides of the disclosure and methods of using and producing same are also disclosed.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: May 7, 2024
    Assignee: OPKO BIOLOGICS LTD.
    Inventors: Oren Hershkovitz, Laura Moschcovich
  • METHODS OF PRODUCING LONG ACTING CTP-MODIFIED POLYPEPTIDES
    Publication number: 20210371487
    Abstract: Disclosed herein is a method for manufacturing a recombinant polypeptide of interest modified by a CTP extension in a mammalian cells culture system.
    Type: Application
    Filed: February 1, 2021
    Publication date: December 2, 2021
    Applicant: OPKO BIOLOGICS LTD.
    Inventors: Oren HERSHKOVITZ, Laura MOSCHCOVICH
  • LONG-ACTING IGF-1 OR IGF-1 VARIANTS AND METHODS OF PRODUCING SAME
    Publication number: 20210008172
    Abstract: Compositions which include polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotropin attached to the carboxy terminus or amino terminus of an insulin-like growth factor 1 (IGF-1) or IGF-1 variant. Polynucleotides encoding the same are disclosed. Pharmaceutical compositions and pharmaceutical formulations comprising the polypeptides and polynucleotides of the invention and methods of using and producing same are also disclosed.
    Type: Application
    Filed: July 9, 2020
    Publication date: January 14, 2021
    Applicant: OPKO Biologics Ltd.
    Inventors: OREN HERSHKOVITZ, Lital Israeli-Yagev, Ahuva Bar-Ilan, Laura Moschcovich, Moran Golan
  • LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME
    Publication number: 20200354430
    Abstract: Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotropin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions and pharmaceutical formulations comprising the polypeptides and polynucleotides of the disclosure and methods of using and producing same are also disclosed.
    Type: Application
    Filed: July 11, 2017
    Publication date: November 12, 2020
    Applicant: OPKO BIOLOGICS LTD.
    Inventors: Oren HERSHKOVITZ, Laura MOSCHCOVICH
  • METHODS OF PRODUCING LONG ACTING CTP-MODIFIED GROWTH HORMONE POLYPEPTIDES
    Publication number: 20180111974
    Abstract: Disclosed herein is a method for manufacturing a recombinant human growth hormone (h GH) modified by a CTP extension in a mammalian cells culture system.
    Type: Application
    Filed: December 10, 2015
    Publication date: April 26, 2018
    Inventors: Oren HERSHKOVITZ, Laura MOSCHCOVICH
  • METHODS OF PRODUCING LONG ACTING CTP-MODIFIED POLYPEPTIDES
    Publication number: 20160168588
    Abstract: Disclosed herein is a method for manufacturing a recombinant polypeptide of interest modified by a CTP extension in a mammalian cells culture system.
    Type: Application
    Filed: December 10, 2015
    Publication date: June 16, 2016
    Applicant: Opko Biologics Ltd
    Inventors: Oren HERSHKOVITZ, Laura Moschcovich