Patents by Inventor Laura PHILIPS

Laura PHILIPS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Holographic characterization of irregular particles
    Patent number: 11921023
    Abstract: Holographic Video Microscopy analysis of non-spherical particles is disclosed herein. Properties of the particles are determined by application of light scattering theory to holography data. Effective sphere theory is applied to provide information regarding the reflective index of a sphere that includes a target particle. Known particles may be co-dispersed with unknown particles in a medium and the holographic video microscopy is used to determine properties, such as porosity, of the unknown particles.
    Type: Grant
    Filed: December 30, 2022
    Date of Patent: March 5, 2024
    Assignees: New York University, Spheryx, Inc.
    Inventors: David G. Grier, Mary Ann Odete, Fook Chiong Cheong, Annemarie Winters, Jesse J. Elliott, Laura A. Philips
  • Holographic characterization of protein aggregates
    Patent number: 11747258
    Abstract: Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.
    Type: Grant
    Filed: May 27, 2022
    Date of Patent: September 5, 2023
    Assignee: New York University
    Inventors: David G. Grier, Michael D. Ward, Xiao Zhong, Chen Wang, Laura A. Philips, David B. Ruffner, Fook Chiong Cheong
  • HOLOGRAPHIC CHARACTERIZATION OF IRREGULAR PARTICLES
    Publication number: 20230213425
    Abstract: Holographic Video Microscopy analysis of non-spherical particles is disclosed herein. Properties of the particles are determined by application of light scattering theory to holography data. Effective sphere theory is applied to provide information regarding the reflective index of a sphere that includes a target particle. Known particles may be co-dispersed with unknown particles in a medium and the holographic video microscopy is used to determine properties, such as porosity, of the unknown particles.
    Type: Application
    Filed: December 30, 2022
    Publication date: July 6, 2023
    Applicants: NEW YORK UNIVERSITY, SPHERYX, INC.
    Inventors: David G. GRIER, Mary Ann ODETE, Fook Chiong CHEONG, Annemarie WINTERS, Jesse J. ELLIOTT, Laura A. PHILIPS
  • HOLOGRAPHIC VIDEO MICROSCOPY CELL VIABILITY ASSAY
    Publication number: 20230137843
    Abstract: A holographic microscopy characterization (HMC) process for utilizing holographic video microscopy to provide an efficient, automated, label-free method of accurately identifying cell viability. Optical properties of a sample of cells are determined by HMC. The optical properties are compared to known samples or compared over time to observe changes in the optical properties, enabling identification of cells as viable or not viable, or as extra-cellular or degraded cellular materials.
    Type: Application
    Filed: October 28, 2022
    Publication date: May 4, 2023
    Applicant: SPHERYX, INC.
    Inventors: Mary Ann ODETE, Rostislav BOLTYANSKIY, Fook Chiong CHEONG, Laura A. PHILIPS
  • Holographic characterization of irregular particles
    Patent number: 11543338
    Abstract: Holographic Video Microscopy analysis of non-spherical particles is disclosed herein. Properties of the particles are determined by application of light scattering theory to holography data. Effective sphere theory is applied to provide information regarding the reflective index of a sphere that includes a target particle. Known particles may be co-dispersed with unknown particles in a medium and the holographic video microscopy is used to determine properties, such as porosity, of the unknown particles.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: January 3, 2023
    Assignees: New York University, Spheryx, Inc.
    Inventors: David G. Grier, Mary Ann Odete, Fook Chiong Cheong, Annemarie Winters, Jesse J. Elliott, Laura A. Philips
  • HOLOGRAPHIC CHARACTERIZATION OF PROTEIN AGGREGATES
    Publication number: 20220326130
    Abstract: Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.
    Type: Application
    Filed: May 27, 2022
    Publication date: October 13, 2022
    Applicant: NEW YORK UNIVERSITY
    Inventors: David G. Grier, Michael D. WARD, Xiao ZHONG, Chen WANG, Laura A. PHILIPS, David B. RUFFNER, Fook Chiong CHEONG
  • Holographic characterization of protein aggregates
    Patent number: 11385157
    Abstract: Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: July 12, 2022
    Assignee: New York University
    Inventors: David G. Grier, Michael D. Ward, Xiao Zhong, Chen Wang, Laura A. Philips, David B. Ruffner, Fook Chiong Cheong
  • Holographic characterization of protein aggregates
    Patent number: 11346761
    Abstract: Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: May 31, 2022
    Assignee: New York University
    Inventors: David G. Grier, Michael D. Ward, Xiao Zhong, Chen Wang, Laura A. Philips, David B. Ruffner, Fook Chiong Cheong
  • HOLOGRAPHIC CHARACTERIZATION OF PROTEIN AGGREGATES
    Publication number: 20210199551
    Abstract: Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.
    Type: Application
    Filed: February 7, 2017
    Publication date: July 1, 2021
    Inventors: David G. GRIER, Michael D. WARD, Xiao ZHONG, Chen WANG, Laura A. PHILIPS, David B. RUFFNER, Fook Chiong CHEONG
  • HOLOGRAPHIC CHARACTERIZATION OF IRREGULAR PARTICLES
    Publication number: 20210123848
    Abstract: Holographic Video Microscopy analysis of non-spherical particles is disclosed herein. Properties of the particles are determined by application of light scattering theory to holography data. Effective sphere theory is applied to provide information regarding the reflective index of a sphere that includes a target particle. Known particles may be co-dispersed with unknown particles in a medium and the holographic video microscopy is used to determine properties, such as porosity, of the unknown particles.
    Type: Application
    Filed: October 23, 2020
    Publication date: April 29, 2021
    Inventors: David G. GRIER, Mary Ann ODETE, Fook Chiong CHEONG, Annemarie WINTERS, Jesse J. ELLIOTT, Laura A. PHILIPS
  • Holographic detection and characterization of large impurity particles in precision slurries
    Patent number: 10641696
    Abstract: Impurities within a sample are detected by use of holographic video microscopy. The sample flows through the microscope and holographic images are generated. The holographic image is analyzed to identify regions associated with large impurities in the sample. The contribution of the particles of the sample to the holographic images is determined and the impurities are characterized.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: May 5, 2020
    Assignee: NEW YORK UNIVERSITY
    Inventors: David B. Ruffner, David G. Grier, Laura Philips
  • HOLOGRAPHIC CHARACTERIZATION USING HU MOMENTS
    Publication number: 20190234853
    Abstract: Holographic microscopy analysis system and methods for determining morphology of a particle in a sample. A bright-field reconstruction image is generated from a recorded hologram from a holographic microscopy system. Morphology of particles imaged by the system may be determined. Hu moments are calculated, either from the hologram or from the bright-field reconstruction, or both, to provide an indication of morphology.
    Type: Application
    Filed: August 24, 2017
    Publication date: August 1, 2019
    Inventors: David B. RUFFNER, Laura PHILIPS, Fook Chiong CHEONG
  • HOLOGRAPHIC DETECTION AND CHARACTERIZATION OF LARGE IMPURITY PARTICLES IN PRECISION SLURRIES
    Publication number: 20180252628
    Abstract: Impurities within a sample are detected by use of holographic video microscopy. The sample flows through the microscope and holographic images are generated. The holographic image is analyzed to identify regions associated with large impurities in the sample. The contribution of the particles of the sample to the holographic images is determined and the impurities are characterized.
    Type: Application
    Filed: September 15, 2016
    Publication date: September 6, 2018
    Inventors: David B. RUFFNER, David G. GRIER, Laura PHILIPS