Patents by Inventor Laura Poliseno

Laura Poliseno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Micro-RNA inhibitors and their uses in disease
    Patent number: 11274301
    Abstract: The invention relates to the treatment and prevention of cancer by administering agents that inhibit the activity of microRNAs that modulate tumor suppressor genes, which can include PTEN, p53, and INPP4B, among others. Inhibitors can include oligonucleotides that are at least partially complementary to these miRNAs. In some embodiments, these inhibitors are chemically modified oligonucleotides, including locked nucleic acids (LNAs).
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: March 15, 2022
    Assignee: BETH ISRAEL DEACONESS MEDICAL CENTER
    Inventors: Pier Paolo Pandolfi, Laura Poliseno, Yvonne Tay, Leonardo Salmena
  • Micro-RNA inhibitors and their uses in disease
    Patent number: 10131905
    Abstract: The invention relates to the treatment and prevention of cancer by administering agents that inhibit the activity of microRNAs that modulate tumor suppressor genes, which can include PTEN, p53, and INPP4B, among others. Inhibitors can include oligonucleotides that are at least partially complementary to these miRNAs. In some embodiments, these inhibitors are chemically modified oliognucleotides, including locked nucleic acids (LNAs).
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: November 20, 2018
    Assignee: BETH ISRAEL DEACONESS MEDICAL CENTER
    Inventors: Pier Paolo Pandolfi, Laura Poliseno, Yvonne Tay, Leonardo Salmena
  • Micro-RNA Inhibitors and Their Uses in Disease
    Publication number: 20180073025
    Abstract: The invention relates to the treatment and prevention of cancer by administering agents that inhibit the activity of microRNAs that modulate tumor suppressor genes, which can include PTEN, p53, and INPP4B, among others. Inhibitors can include oligonucleotides that are at least partially complementary to these miRNAs. In some embodiments, these inhibitors are chemically modified oliognucleotides, including locked nucleic acids (LNAs).
    Type: Application
    Filed: October 6, 2017
    Publication date: March 15, 2018
    Inventors: Pier Paolo Pandolfi, Laura Poliseno, Yvonne Tay, Leonardo Salmena
  • MICRO-RNA INHIBITORS AND THEIR USES IN DISEASE
    Publication number: 20150126579
    Abstract: The invention relates to the treatment and prevention of cancer by administering agents that inhibit the activity of microRNAs that modulate tumor suppressor genes, which can include PTEN, p53, and INPP4B, among others. Inhibitors can include oligonucleotides that are at least partially complementary to these miRNAs. In some embodiments, these inhibitors are chemically modified oliognucleotides, including locked nucleic acids (LNAs).
    Type: Application
    Filed: April 12, 2012
    Publication date: May 7, 2015
    Applicant: BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
    Inventors: Pier Paolo Pandolfi, Laura Poliseno, Yvonne Tay, Leonardo Salmena