Patents by Inventor Laura S. Grosmaire

Laura S. Grosmaire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD37 immunotherapeutics and uses thereof
    Patent number: 10307481
    Abstract: The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: June 4, 2019
    Assignee: Aptevo Research and Development LLC
    Inventors: Laura S. Grosmaire, Martha S. Hayden-Ledbetter, Jeffrey A. Ledbetter, Peter A. Thompson, Sandy A. Simon, William Brady
  • B-CELL REDUCTION USING CD37-SPECIFIC AND CD20-SPECIFIC BINDING MOLECULES
    Publication number: 20090214539
    Abstract: The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.
    Type: Application
    Filed: May 7, 2009
    Publication date: August 27, 2009
    Applicant: Trubion Pharmaceuticals, Inc.
    Inventors: Laura S. Grosmaire, Martha S. Hayden-Ledbetter, Jeffrey A. Ledbetter, Peter A. Thompson, Sandy A. Simon, William Brady
  • Compositions and methods for regulating lymphocyte activation
    Publication number: 20040253250
    Abstract: The present invention relates to regulation of lymphocyte activation. In particular, it relates to compositions and methods for regulating lymphocyte activation by selectively binding multiple cell surface antigens expressed by the same lymphocyte.
    Type: Application
    Filed: August 21, 2003
    Publication date: December 16, 2004
    Applicant: XCYTE Therapies, Inc.
    Inventors: Jeffrey A. Ledbetter, Martha Hayden-Ledbetter, William A. Brady, Laura S. Grosmaire, Che-Leung Law, Raj Dua
  • COMPOSITIONS AND METHODS FOR REGULATING LYMPHOCYTE ACTIVATION
    Publication number: 20020155604
    Abstract: The present invention relates to regulation of lymphocyte activation. In particular, it relates to compositions and methods for regulating lymphocyte activation by selectively binding multiple cell surface antigens expressed by the same lymphocyte.
    Type: Application
    Filed: February 18, 1999
    Publication date: October 24, 2002
    Inventors: JEFFREY A. LEDBETTER, MARTHA HAYDEN LEDBETTER, WILLIAM A. BRADY, LAURA S. GROSMAIRE, CHE-LEUNG LAW, RAJ DUA