Patents by Inventor Laura Sacolick

Laura Sacolick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11467239
    Abstract: A magnetic resonance imaging (MRI) system, comprising: a magnetics system comprising: a B0 magnet configured to provide a B0 field for the MRI system; gradient coils configured to provide gradient fields for the MRI system; and at least one RF coil configured to detect magnetic resonance (MR) signals; and a controller configured to: control the magnetics system to acquire MR spatial frequency data using non-Cartesian sampling; and generate an MR image from the acquired MR spatial frequency data using a neural network model comprising one or more neural network blocks including a first neural network block, wherein the first neural network block is configured to perform data consistency processing using a non-uniform Fourier transformation.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: October 11, 2022
    Assignee: Hyperfine Operations, Inc.
    Inventors: Jo Schlemper, Seyed Sadegh Mosheni Salehi, Michal Sofka, Prantik Kundu, Ziyi Wang, Carole Lazarus, Hadrien A. Dyvorne, Laura Sacolick, Rafael O'Halloran, Jonathan M. Rothberg
  • Publication number: 20220283253
    Abstract: Techniques are provided for imaging a subject. The method may comprise receiving an indication to image the subject using an magnetic resonance imaging (MRI) system, and in response to receiving the indication, with at least one controller: generating, using at least one RF coil, an initial MR data set for generating an initial image of the subject; determining, using the initial MR image, a difference in orientation between a current orientation of the subject in the initial MR image and a target orientation of the subject; determining, using the determined difference in orientation, an adjustment to a gradient pulse sequence for controlling at least one gradient coil; applying the determined adjustment to the gradient pulse sequence to obtain an adjusted gradient pulse sequence; generating an adjusted MR data set using the adjusted gradient pulse sequence; and generating a second MR image of the subject using the adjusted MR data set.
    Type: Application
    Filed: March 4, 2022
    Publication date: September 8, 2022
    Applicant: Hyperfine Operations, Inc.
    Inventors: Laura Sacolick, Rafael O'Halloran, Hadrien A. Dyvorne, Khan Mohammad Siddiqui, Michal Sofka, Prantik Kundu, Tianrui Luo
  • Patent number: 11422216
    Abstract: Systems and methods for generating a gradient waveform for use by a low-field MRI system to generate a gradient magnetic field are provided herein. The gradient waveform can be determined using first information indicative of the gradient waveform and second information indicative of hardware constraints of the low-field MRI system including a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil. In some embodiments, the gradient waveform can be a trapezoidal gradient waveform determined to have a non-linear ramp-up portion and/or a non-linear ramp-down portion.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: August 23, 2022
    Assignee: Hyperfine Operations, Inc.
    Inventors: Hadrien A. Dyvorne, Laura Sacolick, Rafael O'Halloran, Carole Lazarus, Michael Twieg
  • Publication number: 20220244334
    Abstract: Systems and methods are provided herein for determining whether to extend scanning performed by a magnetic resonance imaging (MRI) system. According to some embodiments, there is provided a method for imaging a subject using an MRI system, comprising: obtaining data for generating at least one magnetic resonance image of the subject by operating the MRI system in accordance with a first pulse sequence; prior to completing the obtaining the data in accordance with the first pulse sequence, determining to collect additional data to augment and/or replace at least some of the obtained data; determining a second pulse sequence to use for obtaining the additional data; and after completing the obtaining the data in accordance with the first pulse sequence, obtaining the additional data by operating the MRI system in accordance with the second pulse sequence.
    Type: Application
    Filed: January 24, 2022
    Publication date: August 4, 2022
    Inventors: Laura Sacolick, Carlos Lazarus, Rafael O'Halloran, Hadrien A. Dyvorne
  • Publication number: 20220214417
    Abstract: A magnetic resonance imaging (MRI) system, comprising: a magnetics system comprising: a B0 magnet configured to provide a B0 field for the MRI system; gradient coils configured to provide gradient fields for the MRI system; and at least one RF coil configured. to detect magnetic resonance (MR) signals; and a controller configured to: control the magnetics system to acquire MR spatial frequency data using non-Cartesian sampling; and generate an MR image from the acquired MR spatial frequency data using a neural network model comprising one or more neural network blocks including a first neural network block, wherein the first neural network block is configured to perform data consistency processing using a non-uniform Fourier transformation.
    Type: Application
    Filed: March 23, 2022
    Publication date: July 7, 2022
    Applicant: Hyperfine Operations, Inc.
    Inventors: Jo Schlemper, Seyed Sadegh Mohseni Salehi, Michal Sofka, Prantik Kundu, Ziyi Wang, Carole Lazarus, Hadrien A. Dyvorne, Laura Sacolick, Rafael O'Halloran, Jonathan M. Rothberg
  • Patent number: 11366188
    Abstract: According to some aspects, a portable magnetic resonance imaging system is provided, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging. The magnetics system comprises a permanent B0 magnet configured to produce a B0 field for the magnetic resonance imaging system, and a plurality of gradient coils configured to, when operated, generate magnetic fields to provide spatial encoding of emitted magnetic resonance signals, a power system comprising one or more power components configured to provide power to the magnetics system to operate the magnetic resonance imaging system to perform image acquisition, and a base that supports the magnetics system and houses the power system, the base comprising at least one conveyance mechanism allowing the portable magnetic resonance imaging system to be transported to different locations.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: June 21, 2022
    Assignee: Hyperfine Operations, Inc.
    Inventors: Michael Stephen Poole, Cedric Hugon, Hadrien A. Dyvorne, Laura Sacolick, William J. Mileski, Jeremy Christopher Jordan, Alan B. Katze, Jr., Jonathan M. Rothberg, Todd Rearick, Christopher Thomas McNulty
  • Patent number: 11333726
    Abstract: Methods and apparatus for operating a low-field magnetic resonance imaging (MRI) system to perform diffusion weighted imaging, the low-field MRI system including a plurality of magnetics components including a B0 magnet configured to produce a low-field main magnetic field B0, at least one gradient coil configured to, when operated, provide spatial encoding of emitted magnetic resonance signals, and at least one radio frequency (RF) component configured to acquire, when operated, the emitted magnetic resonance signals. The method comprises controlling one or more of the plurality of magnetics components in accordance with at least one pulse sequence having a diffusion-weighted gradient encoding period followed by multiple echo periods during which magnetic resonance signals are produced and detected, wherein at least two of the multiple echo periods correspond to respective encoded echoes having an opposite gradient polarity.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: May 17, 2022
    Assignee: Hypefine Operations, Inc.
    Inventors: Rafael O'Halloran, Laura Sacolick
  • Patent number: 11300645
    Abstract: A magnetic resonance imaging (MRI) system, comprising: a magnetics system comprising: a B0 magnet configured to provide a B0 field for the MRI system; gradient coils configured to provide gradient fields for the MRI system; and at least one RF coil configured to detect magnetic resonance (MR) signals; and a controller configured to: control the magnetics system to acquire MR spatial frequency data using non-Cartesian sampling; and generate an MR image from the acquired MR spatial frequency data using a neural network model comprising one or more neural network blocks including a first neural network block, wherein the first neural network block is configured to perform data consistency processing using a non-uniform Fourier transformation.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: April 12, 2022
    Assignee: Hyperfine Operations, Inc.
    Inventors: Jo Schlemper, Seyed Sadegh Moshen Salehi, Michal Sofka, Prantik Kundu, Ziyi Wang, Carole Lazarus, Hadrien A. Dyvorne, Laura Sacolick, Rafael O'Halloran, Jonathan M. Rothberg
  • Publication number: 20220043094
    Abstract: An apparatus for controlling at least one gradient coil of a magnetic resonance imaging (MRI) system. The apparatus may include at least one computer hardware processor; and at least one computer-readable storage medium storing processor executable instructions that, when executed by the at least one computer hardware processor, cause the at least one computer hardware processor to perform a method. The method may include receiving information specifying at least one target pulse sequence; determining a corrected pulse sequence to control the at least one gradient coil based on the at least one target pulse sequence and a hysteresis model of induced magnetization in the MRI system caused by operation of the at least one gradient coil; and controlling, using the corrected gradient pulse sequence, the at least one gradient coil to generate one or more gradient pulses for imaging a patient.
    Type: Application
    Filed: September 24, 2021
    Publication date: February 10, 2022
    Applicant: Hyperfine, Inc.
    Inventors: Rafael O'Halloran, Cedric Hugon, Laura Sacolick, Hadrien A. Dyvorne
  • Publication number: 20210373107
    Abstract: A magnetic resonance imaging (MRI) system and method for acquiring magnetic resonance (MR) images using a pulse sequence implementing driven equilibrium and quadratic phase cycling techniques is provided. The method includes, during a pulse repetition period of a pulse sequence and using a quadratic phase cycling scheme, applying a first RF pulse to deflect a net magnetization vector associated with the subject from a longitudinal plane into a transverse plane; after applying the first RF pulse, applying a first sequence of RF pulses each of which flips the net magnetization vector by approximately 180 degrees within the transverse plane; and after applying the first sequence of RF pulses, applying a second RF pulse to deflect the net magnetization vector from the transverse plane to the longitudinal plane.
    Type: Application
    Filed: May 28, 2021
    Publication date: December 2, 2021
    Applicant: Hyperfine, Inc.
    Inventors: Hadrien A. Dyvorne, Laura Sacolick, Rafael O'Halloran, Carole Lazarus
  • Patent number: 11156688
    Abstract: An apparatus for controlling at least one gradient coil of a magnetic resonance imaging (MRI) system. The apparatus may include at least one computer hardware processor; and at least one computer-readable storage medium storing processor executable instructions that, when executed by the at least one computer hardware processor, cause the at least one computer hardware processor to perform a method. The method may include receiving information specifying at least one target pulse sequence; determining a corrected pulse sequence to control the at least one gradient coil based on the at least one target pulse sequence and a hysteresis model of induced magnetization in the MRI system caused by operation of the at least one gradient coil; and controlling, using the corrected gradient pulse sequence, the at least one gradient coil to generate one or more gradient pulses for imaging a patient.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: October 26, 2021
    Assignee: Hyperfine, Inc.
    Inventors: Rafael O'Halloran, Cedric Hugon, Laura Sacolick, Hadrien A. Dyvorne
  • Publication number: 20210302518
    Abstract: Systems and methods for generating a gradient waveform for use by a low-field MRI system to generate a gradient magnetic field are provided herein. The gradient waveform can be determined using first information indicative of the gradient waveform and second information indicative of hardware constraints of the low-field MRI system including a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil. In some embodiments, the gradient waveform can be a trapezoidal gradient waveform determined to have a non-linear ramp-up portion and/or a non-linear ramp-down portion.
    Type: Application
    Filed: March 23, 2021
    Publication date: September 30, 2021
    Inventors: Hadrien A. Dyvorne, Laura Sacolick, Rafael O'Halloran, Carole Lazarus, Michael Twieg
  • Publication number: 20210302519
    Abstract: Systems and methods for generating a gradient waveform for use by a low-field MRI system to generate a gradient magnetic field are provided herein. The gradient waveform can be determined using first information indicative of the gradient waveform and second information indicative of hardware constraints of the low-field MRI system including a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil. In some embodiments, the gradient waveform can be a trapezoidal gradient waveform determined to have a non-linear ramp-up portion and/or a non-linear ramp-down portion.
    Type: Application
    Filed: March 23, 2021
    Publication date: September 30, 2021
    Inventors: Hadrien A. Dyvorne, Laura Sacolick, Rafael O'Halloran, Carole Lazarus, Michael Twieg
  • Publication number: 20210223340
    Abstract: A low-field magnetic resonance imaging (MRI) system. The system includes a plurality of magnetics components comprising at least one first magnetics component configured to produce a low-field main magnetic field B0 and at least one second magnetics component configured to acquire magnetic resonance data when operated, and at least one controller configured to operate one or more of the plurality of magnetics components in accordance with at least one low-field zero echo time (LF-ZTE) pulse sequence.
    Type: Application
    Filed: March 8, 2021
    Publication date: July 22, 2021
    Applicant: Hyperfine Research, Inc.
    Inventors: Laura Sacolick, Matthew Scot Rosen, Gregory L. Charvat, Jonathan M. Rothberg, Mathieu Sarracanie
  • Publication number: 20210165060
    Abstract: According to some aspects, a low-field magnetic resonance imaging system is provided. The low-field magnetic resonance imaging system comprises a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the magnetics system comprising, a B0 magnet configured to produce a B0 field for the magnetic resonance imaging system at a low-field strength of less than 0.
    Type: Application
    Filed: January 11, 2021
    Publication date: June 3, 2021
    Applicant: Hyperfine Research, Inc,
    Inventors: Michael Stephen Poole, Cedric Hugon, Hadrien A. Dyvorne, Laura Sacolick, William J. Mileski, Jeremy Christopher Jordan, Alan B. Katze, JR., Jonathan M. Rothberg, Todd Rearick, Christopher Thomas McNulty
  • Publication number: 20210153765
    Abstract: Techniques for suppressing noise in an environment of a magnetic resonance (MR) imaging system having at least one primary coil and at least one auxiliary sensor. The techniques involve estimating a transform, that, when applied to noise received by the at least one auxiliary sensor, provides an estimate of noise received by the at least one primary coil. The transform is estimated from data obtained by the at least one primary coil and the least one auxiliary sensor, with the data being weighted prior to estimation to remove or suppress data in regions with a high signal to noise ratio. In turn, the estimated transform may be applied to noise measured by the at least one auxiliary sensor during imaging of a patient, to estimate and suppress noise present in the MR signals received by the at least one primary coil during imaging.
    Type: Application
    Filed: November 19, 2020
    Publication date: May 27, 2021
    Inventors: Laura Sacolick, Hadrien A. Dyvorne
  • Publication number: 20210109174
    Abstract: Methods and apparatus for operating a low-field magnetic resonance imaging (MRI) system to perform diffusion weighted imaging, the low-field MRI system including a plurality of magnetics components including a B0 magnet configured to produce a low-field main magnetic field B0, at least one gradient coil configured to, when operated, provide spatial encoding of emitted magnetic resonance signals, and at least one radio frequency (RF) component configured to acquire, when operated, the emitted magnetic resonance signals. The method comprises controlling one or more of the plurality of magnetics components in accordance with at least one pulse sequence having a diffusion-weighted gradient encoding period followed by multiple echo periods during which magnetic resonance signals are produced and detected, wherein at least two of the multiple echo periods correspond to respective encoded echoes having an opposite gradient polarity.
    Type: Application
    Filed: November 2, 2020
    Publication date: April 15, 2021
    Applicant: Hyperfine Research, Inc.
    Inventors: Rafael O'Halloran, Laura Sacolick
  • Publication number: 20210100474
    Abstract: A magnetic resonance (MR) imaging system, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, and a sensor configured to detect electromagnetic interference conducted by a patient into an imaging region of the MR imaging system. The sensor may comprise at least one electrical conductor configured for electrically coupling to the patient. The MR imaging system may further comprise a noise reduction system configured to receive the electromagnetic interference from the sensor and to suppress electromagnetic interference in detected MR signals received by the MR imaging system based on the electromagnetic interference detected by the sensor.
    Type: Application
    Filed: October 7, 2020
    Publication date: April 8, 2021
    Applicant: Hyperfine Research, Inc.
    Inventors: Hadrien A. Dyvorne, Laura Sacolick, Carole Lazarus, Eddy B. Boskamp, Jeremy Christopher Jordan
  • Publication number: 20210103017
    Abstract: A magnetic resonance (MR) imaging system, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, and a sensor configured to detect electromagnetic interference conducted by a patient into an imaging region of the MR imaging system. The sensor may comprise at least one electrical conductor configured for electrically coupling to the patient. The MR imaging system may further comprise a noise reduction system configured to receive the electromagnetic interference from the sensor and to suppress electromagnetic interference in detected MR signals received by the MR imaging system based on the electromagnetic interference detected by the sensor.
    Type: Application
    Filed: October 7, 2020
    Publication date: April 8, 2021
    Applicant: Hyperfine Research, Inc.
    Inventors: Hadrien A. Dyvorne, Laura Sacolick, Carole Lazarus, Eddy B. Boskamp, Jeremy Christopher Jordan
  • Patent number: 10955500
    Abstract: A low-field magnetic resonance imaging (MRI) system. The system includes a plurality of magnetics components comprising at least one first magnetics component configured to produce a low-field main magnetic field B0 and at least one second magnetics component configured to acquire magnetic resonance data when operated, and at least one controller configured to operate one or more of the plurality of magnetics components in accordance with at least one low-field zero echo time (LF-ZTE) pulse sequence.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: March 23, 2021
    Assignee: Hyperfine Research, Inc.
    Inventors: Laura Sacolick, Matthew Scot Rosen, Gregory L. Charvat, Jonathan M. Rothberg, Mathieu Sarracanie