Abstract: Systems and methods for generating a processed fortified human milk product from raw human milk, and processed fortified human milk product compositions obtained thereby, are provided. The processed fortified human milk product composition possesses high nutritional content such as high concentrations of protein and human milk oligosaccharides. The processed fortified human milk product composition exhibits low overall bioburden and is non-allogenic and non-immunogenic. When ingested by an individual, the processed fortified human milk product composition achieves high bioavailability and reduces inflammatory processes.

Abstract: Systems and methods for generating a sterilized human milk product from raw human milk, and sterilized human milk product compositions obtained thereby, are provided. The method includes sterilizing the milk using a countercurrent heating process. The temperature of the milk is raised to a target temperature for a duration of time that is refined to provide a sterilized human milk product with low overall bioburden while also maintaining nutritional quality. As such, the sterilized milk product is suitable for ingestion by premature infants.