Patents by Inventor Laura Tatjer Recorda

Laura Tatjer Recorda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Demethylation of Reticuline and Derivatives Thereof with Fungal Cytochrome P450
    Publication number: 20240150804
    Abstract: The invention relates to recombinant host cells that expresses one or more genes encoding a cytochrome P450 enzyme capable of N-demethylating and/O-demethylating reticuline and/or derivatives thereof, and also methods of producing a N-demethylated and/or O-demethylated reticuline and/or derivatives thereof, comprising cultivating the recombinant host of the invention in a culture medium under conditions in which the one or more genes encoding the cytochrome P450 enzymes is/are expressed. The reticuline and derivatives thereof are useful for providing access to naturally unavailable and chemically difficult-to-produce starting materials for opioids.
    Type: Application
    Filed: August 18, 2023
    Publication date: May 9, 2024
    Inventors: Markus Schwab, Sumire Honda Malca, Philipp Friedrich Berninger, Jon Richard Heal, Joseph Michael Sheridan, Laura Tatjer Recorda, Rubini Maya Kannangara, Esben Halkjaer Hansen, Angela Manuela Ribeiro de Carvalho
  • Glycosylated Opioids
    Publication number: 20240150805
    Abstract: The present invention relate to a method for producing an oripavine glycoside and/or nororipavine glycoside comprising providing (i) a oripavine acceptor and/or nororipavine acceptor, (ii) a glycosyl donor, and (iii) a glycosyl transferase (UGT), and contacting the oripavine acceptor and/or nororipavine acceptor, the glycosyl donor, and the UGT at conditions allowing the UGT to transfer a glycosyl moiety from the glycosyl donor to the oripavine acceptor and/or nororipavine acceptor and thereby produce the oripavine glycoside and/or nororipavine glycoside.
    Type: Application
    Filed: May 5, 2022
    Publication date: May 9, 2024
    Inventors: Jens Houghton-Larsen, Rubini Kannangara, Esben Halkjaer Hansen, Evan Chaberski, Laura Tatjer-Recordá
  • Demethylation of reticuline and derivatives thereof with fungal cytochrome P450
    Patent number: 11781164
    Abstract: The invention relates to recombinant host cells that expresses one or more genes encoding a cytochrome P450 enzyme capable of N-demethylating and/O-demethylating reticuline and/or derivatives thereof, and also methods of producing a N-demethylated and/or O-demethylated reticuline and/or derivatives thereof, comprising cultivating the recombinant host of the invention in a culture medium under conditions in which the one or more genes encoding the cytochrome P450 enzymes is/are expressed. The reticuline and derivatives thereof are useful for providing access to naturally unavailable and chemically difficult-to-produce starting materials for opioids.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: October 10, 2023
    Assignee: RIVER STONE BIOTECH, LLC
    Inventors: Markus Schwab, Sumire Honda Malca, Philipp Friedrich Berninger, Jon Richard Heal, Joseph Michael Sheridan, Laura Tatjer Recorda, Rubini Maya Kannangara, Esben Halkjaer Hansen, Angela Manuela Ribeiro de Carvalho
  • Demethylation of Reticuline and Derivatives Thereof with Fungal Cytochrome P450
    Publication number: 20210230655
    Abstract: The invention relates to recombinant host cells that expresses one or more genes encoding a cytochrome P450 enzyme capable of N-demethylating and/O-demethylating reticuline and/or derivatives thereof, and also methods of producing a N-demethylated and/or O-demethylated reticuline and/or derivatives thereof, comprising cultivating the recombinant host of the invention in a culture medium under conditions in which the one or more genes encoding the cytochrome P450 enzymes is/are expressed. The reticuline and derivatives thereof are useful for providing access to naturally unavailable and chemically difficult-to-produce starting materials for opioids.
    Type: Application
    Filed: June 18, 2018
    Publication date: July 29, 2021
    Inventors: Markus Schwab, Sumire Honda Malca, Philipp Friedrich Berninger, Jon Richard Heal, Joseph Michael Sheridan, Laura Tatjer Recorda, Rubini Maya Kannangara, Esben Halkjaer Hansen, Angela Manuela Ribeiro de Carvalho
  • PRODUCTION OF STEVIOL GLYCOSIDES IN RECOMBINANT HOSTS
    Publication number: 20210155966
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosides of steviol precursors, and steviol glycoside precursors.
    Type: Application
    Filed: September 8, 2020
    Publication date: May 27, 2021
    Inventors: Kim Olsson, Joseph Michael Sheridan, Laura Tatjer Recorda, Christian Nyffengger, Veronique Douchin
  • Production of steviol glycosides in recombinant hosts
    Patent number: 10815514
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosides of steviol precursors, and steviol glycoside precursors.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: October 27, 2020
    Assignee: Evolva SA
    Inventors: Kim Olsson, Joseph Michael Sheridan, Laura Tatjer Recorda, Christian Nyffengger, Veronique Douchin
  • PRODUCTION OF STEVIOL GLYCOSIDES IN RECOMBINANT HOSTS
    Publication number: 20190153495
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosides of steviol precursors, and steviol glycoside precursors.
    Type: Application
    Filed: May 16, 2017
    Publication date: May 23, 2019
    Applicant: EVOLVA SA
    Inventors: Kim Olsson, Joseph Michael Sheridan, Laura Tatjer Recorda, Christian Nyffengger, Veronique Douchin