Patents by Inventor Laurel Kathryn Mcgrane

Laurel Kathryn Mcgrane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-MANNOSIDE COMPOUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS
    Publication number: 20230287028
    Abstract: Disclosed herein are C-mannoside compounds, compositions thereof and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (CD) and Inflammatory Bowel Disease (IBD).
    Type: Application
    Filed: April 28, 2023
    Publication date: September 14, 2023
    Inventors: Michael Joseph BISHOP, Eugene L. Stewart, Katherine Louisa Widdowson, James Walter Janetka, Laurel Kathryn McGrane
  • C-mannoside compounds useful for the treatment of urinary tract infections
    Patent number: 11697665
    Abstract: Disclosed herein are C-mannoside compounds, compositions thereof and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (CD) and Inflammatory Bowel Disease (IBD).
    Type: Grant
    Filed: July 9, 2021
    Date of Patent: July 11, 2023
    Assignees: Fimbrion Therapeutics, Inc., GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Michael Joseph Bishop, Eugene L. Stewart, Katherine Louisa Widdowson, James Walter Janetka, Laurel Kathryn McGrane
  • NOVEL COMPOUNDS
    Publication number: 20220298197
    Abstract: Disclosed herein are new C-mannoside compounds and compositions and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in human subjects are also provided for the treatment diseases such as urinary tract infection.
    Type: Application
    Filed: May 6, 2020
    Publication date: September 22, 2022
    Inventors: Michael Joseph BISHOP, James Walter JANETKA, Laurel Kathryn MCGRANE, Eugene Lee STEWART, Katherine Louisa WIDDOWSON
  • SUBSTITUTED BIPHENYL OR PHENYLHETEROARYL-MANNOSIDES AS ANTAGONISTS OF FIMH
    Publication number: 20220242900
    Abstract: Disclosed herein are new O-biphenyl- and O-phenylheteroarylmannoside compounds and compositions and their application as pharmaceuticals for use in the treatment of human disease. Methods of inhibition of FimH activity in human subjects are also provided for the treatment of diseases such as urinary tract infection.
    Type: Application
    Filed: June 17, 2020
    Publication date: August 4, 2022
    Inventors: Michael Joseph BISHOP, James Walter JANETKA, Laurel Kathryn MCGRANE, Katherine Louisa WIDDOWSON
  • C-MANNOSIDE COMPOUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS
    Publication number: 20210395287
    Abstract: Disclosed herein are C-mannoside compounds, compositions thereof and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (CD) and Inflammatory Bowel Disease (IBD).
    Type: Application
    Filed: July 9, 2021
    Publication date: December 23, 2021
    Inventors: Michael Joseph BISHOP, Eugene L. STEWART, Katherine Louisa WIDDOWSON, James Walter JANETKA, Laurel Kathryn MCGRANE
  • C-mannoside compounds useful for the treatment of urinary tract infections
    Patent number: 11111262
    Abstract: Disclosed herein are new C-mannoside compounds and compositions and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment diseases such as urinary tract infection.
    Type: Grant
    Filed: October 6, 2020
    Date of Patent: September 7, 2021
    Assignees: GlaxoSmithKline Intellectual Property Development Limited, Fimbrion Therapeutics, Inc.
    Inventors: Michael Joseph Bishop, Eugene L. Stewart, Katherine Louisa Widdowson, James Walter Janetka, Laurel Kathryn McGrane
  • C-MANNOSIDE COMPOUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS
    Publication number: 20210017212
    Abstract: Disclosed herein are new C-mannoside compounds and compositions and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment diseases such as urinary tract infection.
    Type: Application
    Filed: October 6, 2020
    Publication date: January 21, 2021
    Inventors: Michael Joseph BISHOP, Vincent J. Colandrea, Yuehu Li, Eugene L. Stewart, Iulia Strambeanu, Katherine Louisa Widdowson, James Walter Janetka, Laurel Kathryn Mcgrane