Abstract: Implementations of a device configured to induce vasodilation of a superficial vein and methods of using the device are provided. The device is configured to ease the process of venipuncture by increasing blood flow to a superficial vein. The device is configured to increase local blood flow to a superficial vein by applying heat and/or vibration at, or near, a prospective puncture site. In this way, vasodilation of the superficial vein may be induced. The device comprises a strap, a flexible heating element, at least one vibration element, a power source, and an ON/OFF switch for selectively energizing both the heating element and the at least one vibration element. In some implementations, the device may further comprise a thermal control switch configured to vary the temperature reached by the heating element and/or a vibratory element control switch configured to vary the vibratory intensity of the at least one vibration element.