Patents by Inventor Lauren Olinski

Lauren Olinski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Humanized complement 5A receptor 1 antibodies and methods of use thereof
    Patent number: 11912781
    Abstract: The present disclosure provides, among other things, two different formats of humanized antibodies against human complement component 5a receptor I. The disclosure also provides a method of treating a subject having dysfunctions of C5a/C5aR1 axis pathway, including but not limited to ANCA-associated vasculitis, comprising administering to the subject in need thereof a an effective amount of antibody or a nucleic encoding an antibodies binding to C5aR1 described herein, and wherein administering results in a decrease in symptoms associated with C5a/C5aR1 associated dysfunction in the subject.
    Type: Grant
    Filed: January 13, 2022
    Date of Patent: February 27, 2024
    Assignee: Visterra, Inc.
    Inventors: Karthik Viswanathan, Brian Booth, Boopathy Ramakrishnan, Andrew Wollacott, Gregory Babcock, Zachary Shriver, Lauren Olinski
  • IMMUNOSILENCING Fc VARIANTS
    Publication number: 20230416372
    Abstract: The present disclosure provides, among other things Fc variants that have significantly reduced ADCC, ADCP and CDC function As described herein, the present disclosure is, in part based on identification of novel combinations of mutations that abolish binding to all Fc?RI, Fc?RIIa, Fc?RIIb, Fc?RIIIa, Fc?RIIb, and C1q.
    Type: Application
    Filed: August 29, 2023
    Publication date: December 28, 2023
    Applicant: VISTERRA, INC.
    Inventors: Karthik Viswanathan, Lauren Olinski, Ramki Ramakrishnan, Aditi Deshpande, Gregory Babcock, Zachary Shriver