Abstract: A device is provided for overcoming freezing of gait. Suitably, the device includes a sleeve sized and shaped to be worn on a leg of a human subject, an array of electrodes carried by the sleeve and positioned to make surface contact with a skin of the leg when the sleeve is worn on by the human subject, and a controller in communication with the array of electrodes. The controller is operative to receive muscle activity data from the array of electrodes indicative of muscle activity in the leg, identify an onset of a freezing of gait episode based on the received muscle activity data, and trigger energization of one or more targeted electrodes in response to identification of the onset of the freezing of gait episode to mitigate against the freezing of gait episode.

Abstract: In a method of neurological assessment, multichannel electromyography (EMG) data are acquired for an anatomical region. A pairwise EMG channel-EMG channel similarity matrix is generated from the acquired multichannel EMG data. Network analysis is performed on the similarity matrix to generate a network representing the similarity matrix. One or more metrics of the network are computed. One or more biomarkers are determined for the anatomical region based on the one or more metrics. In another method, EMG data are acquired using an electrode array contacting skin of a target anatomy, the EMG data are processed to produce reduced-dimensionality data; and time-invariant muscle synergies and corresponding time-varying activation functions are determined in the reduced-dimensionality data.