Abstract: Provided is a chimeric antigen receptor (CAR) comprising a domain that binds a V? region of a T cell receptor. Also provided is a T cell genetically modified to express the CAR, and methods for treating cancer in a subject in need thereof.

Abstract: The present invention discloses a load-bearing interactive pole video display system. This device allows for graphical video content to be displayed on the surface of a load-bearing pole-shaped structure that may be used in applications such as, but not limited to, railings, beams and dance poles. The core components of the invention are load-bearing internal structure, LED display, light transmissive covering, modular end fittings, power source, sensing and control electronics, which, generally speaking, are configured as follows: the LEDs are mounted to the internal load-bearing structure contained within the external light transmissive tube. Located at one or both ends of the railing are modular end fittings, which allow for connecting power, data and mechanical attachment of the pole or railing to support structures such as permanent or impermanent infrastructure or other modular installations.

Abstract: The present invention provides a method of producing trehalulose, the method comprising: (a) contacting a sucrose solution with a sucrose isomerase enzyme to produce a sucrose-enzyme mixture; and (b) incubating the sucrose-enzyme mixture of (a) at a temperature of less than 10° C. for a period of time sufficient to convert the sucrose in the sucrose-enzyme mixture to a product comprising trehalulose.