Patents by Inventor Laurence Françoise Bernadette Marconnet-Decrane

Laurence Françoise Bernadette Marconnet-Decrane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
    Patent number: 9078896
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: July 14, 2015
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Laurence Francoise Bernadette Marconnet-Decrane, Sandrine Francoise Dominique Gaurrand, Patrick René Angibaud
  • Quinolinone derivatives as PARP and tank inhibitors
    Patent number: 8778966
    Abstract: The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, n, m and X have defined meanings.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: July 15, 2014
    Assignee: Janssen Pharmaceutica, NV
    Inventors: Jorge Eduardo Vialard, Patrick René Angibaud, Laurence Anne Mevellec, Christophe Meyer, Eddy Jean Edgard Freyne, Isabelle Noëlle Constance Pilatte, Bruno Roux, Elisabeth Thèrése Jeanne Pasquier, Xavier Marc Bourdrez, Christophe Denis Adelinet, Laurence Françoise Bernadette Marconnet-Decrane, Jacqueline Anne Macritchie, James Edward Stewart Duffy, Andrew Pate Owens, Pierre-Henri Storck, Virginie Sophie Poncelet
  • Pyridine And Pyrimidine Derivatives As Inhibitors Of Histone Deacetylase
    Publication number: 20140135341
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: January 10, 2014
    Publication date: May 15, 2014
    Applicant: JANSSEN PHARMACEUTICA N.V.
    Inventors: Laurence Francoise Bernadette MARCONNET-DECRANE, Sandrine Francoise Dominique GAURRAND, Patrick René ANGIBAUD
  • Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
    Patent number: 8664223
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: January 10, 2012
    Date of Patent: March 4, 2014
    Assignee: Janssen Pharmaceutica N.V
    Inventors: Laurence Françoise Bernadette Marconnet-Decrane, Sandrine Françoise Dominique Gaurrand, Patrick René Angibaud
  • PYRIDINE AND PYRIMIDINE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE
    Publication number: 20130143898
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: January 10, 2012
    Publication date: June 6, 2013
    Applicant: JANSSEN PHARMACEUTICA N.V.
    Inventors: Laurence Françoise Bernadette MARCONNET-DECRANE, Sandrine Françoise Dominique Gaurrand, Patrick René Angibaud
  • Substituted propenyl piperazine derivatives as novel inhibitors of histone deacetylase
    Patent number: 8426416
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: April 23, 2013
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Sven Franciscus Anna Van Brandt, Kristof Van Emelen, Patrick Rene Angibaud, Laurence Francoise Bernadette Marconnet-Decrane, Janine Arts
  • Quinolinone derivatives as PARP inhibitors
    Patent number: 8404713
    Abstract: Compounds of formula (I): wherein R1, R2, R3, R4, R5, Z and n have defined meanings, the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary ammonium salts and the stereochemically isomeric forms thereof, and their use for the treatment of PARP-mediated disorders.
    Type: Grant
    Filed: October 22, 2008
    Date of Patent: March 26, 2013
    Assignee: Janssen Pharmaceutica NV
    Inventors: Patrick René Angibaud, Laurence Françoise Bernadette Marconnet-Decrane, Jorge Eduardo Vialard, Laurence Anne Mevellec, Christophe Meyer, Pierre-Henri Storck
  • Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase
    Patent number: 8377935
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: February 19, 2013
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Patrick René Angibaud, Laurence Françoise Bernadette Marconnet-Decrane, Sven Franciscus Anna Van Brandt, Isabelle Noëlle Constance Pilatte
  • QUINOLINONE DERIVATIVES AS PARP AND TANK INHIBITORS
    Publication number: 20130018017
    Abstract: The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, n, m and X have defined meanings.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 17, 2013
    Inventors: Jorge Eduardo VIALARD, Patrick René ANGIBAUD, Laurence Anne MEVELLEC, Christophe MEYER, Eddy Jean Edgard FREYNE, Isabelle Noëlle Constance PILATTE, Bruno ROUX, Elizabeth Thérèse Jeanne PASQUIER, Xavier Marc BOURDREZ, Christophe Denis ADELINET, Laurence Françoise Bernadette MARCONNET-DECRANE, Jacqueline Anne MACRITCHIE, James Edward Stewart DUFFY, Andrew Pate OWENS, Pierre-Henri STORCK, Virginie Sophie PONCELET
  • Quinolinone derivatives as PARP and TANK inhibitors
    Patent number: 8299256
    Abstract: The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, n, m and X have defined meanings.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: October 30, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: Jorge Eduardo Vialard, Patrick René Angibaud, Laurence Anne Mevellec, Christophe Meyer, Eddy Jean Edgard Freyne, Isabelle Noëlle Constance Pilatte, Bruno Roux, Elisabeth Thérèse Jeanne Pasquier, Xavier Marc Bourdrez, Christophe Denis Adelinet, Laurence Françoise Bernadette Marconnet-Decrane, Jacqueline Anne Macritchie, James Edward Stewart Duffy, Andrew Pate Owens, Pierre-Henri Storck, Virginie Sophie Poncelet
  • SUBSTITUTED AMINOPROPENYL PIPERIDINE OR MORPHOLINE DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
    Publication number: 20120157456
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: November 22, 2011
    Publication date: June 21, 2012
    Applicant: JANSSEN PHARMACEUTICA N.V.
    Inventors: Patrick René Angibaud, Laurence Françoise Bernadette Marconnet-Decrane, Sven Franciscus Anna Van Brandt, Isabelle Noëlle Constance Pilatte
  • Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase
    Patent number: 8138198
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: March 20, 2012
    Inventors: Patrick René Angibaud, Laurence Françoise Bernadette Marconnet-Decrane, Sven Franciscus Anna Van Brandt, Isabelle Noëlle Constance Pilatte
  • Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
    Patent number: 8114876
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: February 14, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Laurence Françoise Bernadette Marconnet-Decrane, Sandrine Françoise Dominique Gaurrand, Patrick René Angibaud
  • Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
    Patent number: 8101616
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: January 24, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Patrick René Angibaud, Laurence Françoise Bernadette Marconnet-Decrane, Janine Arts
  • SUBSTITUTED PROPENYL PIPERAZINE DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
    Publication number: 20110237585
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: March 15, 2011
    Publication date: September 29, 2011
    Applicant: JANSSEN PHARMACEUTICA N.V.
    Inventors: Sven Franciscus Anna Van Brandt, Kristof Van Emelen, Patrick René Angibaud, Laurence Françoise Bernadette Marconnet-Decrane, Janine Arts
  • Substituted propenyl piperazine derivatives as novel inhibitors of histone deacetylase
    Patent number: 7947830
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: May 24, 2011
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Sven Franciscus Anna Van Brandt, Kristof Van Emelen, Patrick René Angibaud, Laurence Françoise Bernadette Marconnet-Decrane, Janine Arts
  • Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
    Patent number: 7888360
    Abstract: This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, X, Y and Z have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: February 15, 2011
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Patrick René Angibaud, Sven Franciscus Anna Van Brandt, Laurence Françoise Bernadette Marconnet-Decrane, Bruno Roux
  • QUINOLINONE DERIVATIVES AS PARP INHIBITORS
    Publication number: 20100222348
    Abstract: Compounds of formula (I): wherein R1, R2, R3, R4, R5, Z and n have defined meanings, the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary ammonium salts and the stereochemically isomeric forms thereof, and their use for the treatment of PARP-mediated disorders.
    Type: Application
    Filed: October 22, 2008
    Publication date: September 2, 2010
    Inventors: Patrick René Angibaud, Laurence Francoise Bernadette Marconnet-Decrane, Jorge Eduardo Vialard, Laurence Anne Mevellec, Christophe Meyer, Pierre-Henri Storck
  • QUINOLINONE DERIVATIVES AS PARP AND TANK INHIBITORS
    Publication number: 20100168065
    Abstract: The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, n, m and X have defined meanings.
    Type: Application
    Filed: March 7, 2008
    Publication date: July 1, 2010
    Applicant: Janssen Pharmaceutica NV
    Inventors: Jorge Eduardo Vialard, Patrick René Angibaud, Laurence Anne Mevellec, Christophe Meyer, Eddy Jean Edgard Freyne, Isabelle Noëlle Pilatte, Bruno Roux, Elisabeth Thérèse Jeanne Pasquier, Xavier Marc Bourdrez, Christophe Denis Adelinet, Laurence Francoise Bernadette Marconnet-Decrane, Jacqueline Anne Macritchie, James Edward Stewart Duffy, Andrew Pate Owens, Pierre-Henri Storck, Virginie Sophie Poncelet