Abstract: Various embodiments disclose systems and methods for tracking regions (e.g., tumor locations) within living organisms. Some embodiments provide real-time, highly accurate, low latency measurements of tumor location even as the tumor moves with internal body motions. Such measurements may be suitable for closed-loop radiation delivery applications where radiation therapy may be continuously guided to the tumor site even as the tumor moves. Tumor motion may be associated with periodic motion (e.g., respiratory, cardiac) or aperiodic motion (e.g., gross patient motion, internal bowel motion). Various embodiments facilitate accurate radiation delivery to tumor sites exhibiting significant motion, e.g., lung, breast, and liver tumors.

Abstract: A receiver for determining the location of a marker that is excited with an exciting waveform. A sensing array having coils is used to sense magnetic flux from the resonating marker. The coils provide inputs to the receiver. The receiver includes a correlation processor for analyzing the inputs in a coherent manner. Further, the receiver is adapted to tune to the resonant frequency of a marker.

Abstract: Various embodiments disclose systems and methods for tracking regions (e.g., tumor locations) within living organisms. Some embodiments provide real-time, highly accurate, low latency measurements of tumor location even as the tumor moves with internal body motions. Such measurements may be suitable for closed-loop radiation delivery applications where radiation therapy may be continuously guided to the tumor site even as the tumor moves. Tumor motion may be associated with periodic motion (e.g., respiratory, cardiac) or aperiodic motion (e.g., gross patient motion, internal bowel motion). Various embodiments facilitate accurate radiation delivery to tumor sites exhibiting significant motion, e.g., lung, breast, and liver tumors.

Abstract: Embodiments of the invention are directed to an apparatus for use in a system that senses an excitable wireless target capable of being implanted in a body or tissue. The apparatus includes multiple electromagnetic field sensors arranged approximately in a common plane, and multiple sense signal output paths coupled to the sensors. Each one of the sensors and corresponding output paths is configured to provide an output signal representing at least a portion of an electromagnetic field provided by the marker, where the output signal is proportional to a component of the field at the sensor, where that component is substantially perpendicular to the plane. Various other configurations regarding this apparatus, as well as the overall system and methods of exciting and receiving signals from wireless markers, are also disclosed.

Abstract: Embodiments of the invention are directed to an apparatus for use in a system that senses an excitable wireless target capable of being implanted in a body or tissue. The apparatus includes multiple electromagnetic field sensors arranged approximately in a common plane, and multiple sense signal output paths coupled to the sensors. Each one of the sensors and corresponding output paths is configured to provide an output signal representing at least a portion of an electromagnetic field provided by the marker, where the output signal is proportional to a component of the field at the sensor, where that component is substantially perpendicular to the plane. Various other configurations regarding this apparatus, as well as the overall system and methods of exciting and receiving signals from wireless markers, are also disclosed.

Abstract: A receiver for determining the location of a marker that is excited with an exciting waveform. A sensing array having coils is used to sense magnetic flux from the resonating marker. The coils provide inputs to the receiver. The receiver includes a correlation processor for analyzing the inputs in a coherent manner. Further, the receiver is synchronized to act on inputs that are gathered when a treatment radiation source is inactive.

Abstract: Attenuation caused by dispersion in an optical fiber communications system is compensated. A number of low-speed channels is to be transmitted across an optical fiber. Each low-speed channel is allocated a different frequency band for transmission. The attenuation caused by dispersion is estimated for each of the frequency bands. The power of each low-speed channel is adjusted to compensate for the estimated attenuation. The power-adjusted low-speed channels are frequency division multiplexed together to produce an electrical high-speed channel suitable for transmission across the communications system.

Abstract: A heterodyne communication system uses coherent data modulation that is resistant to phase noise. In particular, a pilot tone and reference clock signal are transmitted along with the modulated data to form the basis of an electrical demodulation local oscillator at the receiver. The pilot tone and/or reference clock signal carry phase noise which is correlated with the phase noise in the data signal. At the receiver, the local oscillator is generated from the pilot tone and reference clock signal in a manner so that the local oscillator also has phase noise which is correlated with the phase noise in the data signal. Thus, the two noise components can be used to cancel each other during demodulation of the data signal using the local oscillator.

Abstract: Systems and methods for locating and tracking a target, i.e., measuring the position and/or rotation of a target during setup and treatment of a patient in guided radiation therapy applications for the head and neck. One embodiment is directed toward a device having a body and markers, such as excitable transponders and/or radiographic fiducials, fixable in or on the body for localizing the body. For example, the body can be a mouthpiece body having a channel configured to receive a patient's teeth such that the mouthpiece is repeatedly and consistently placed in the same relative position in the patient when the patient bites down on the mouthpiece. The transponders can be alternating magnetic transponders and the fiducials can be gold seeds. Other embodiments include a device having a two-piece body, a first piece of the body having excitable transponders and a second piece of the body having radiographic fiducials.

Abstract: A transmitter subsystem generates an optical signal which contains multiple subbands of information. The subbands have different polarizations. For example, in one approach, two or more optical transmitters generate optical signals which have different polarizations. An optical combiner optically combines the optical signals into a composite optical signal for transmission across an optical fiber. In another aspect, each optical transmitter generates an optical signal containing both a lower optical sideband and an upper optical sideband (i.e., a double sideband optical signal). An optical filter selects the upper optical sideband of one optical signal and the lower optical sideband of another optical signal to produce a composite optical signal.

Abstract: A heterodyne communication system uses coherent data modulation that is resistant to phase noise. In particular, a pilot tone and reference clock signal are transmitted along with the modulated data to form the basis of an electrical demodulation local oscillator at the receiver. The pilot tone and/or reference clock signal carry phase noise which is correlated with the phase noise in the data signal. At the receiver, the local oscillator is generated from the pilot tone and reference clock signal in a manner so that the local oscillator also has phase noise which is correlated with the phase noise in the data signal. Thus, the two noise components can be used to cancel each other during demodulation of the data signal using the local oscillator.

Abstract: A heterodyne communication system uses coherent data modulation that is resistant to phase noise. In particular, a pilot tone and reference clock signal are transmitted along with the modulated data to form the basis of an electrical demodulation local oscillator at the receiver. The pilot tone and/or reference clock signal carry phase noise which is correlated with the phase noise in the data signal. At the receiver, the local oscillator is generated from the pilot tone and reference clock signal in a manner so that the local oscillator also has phase noise which is correlated with the phase noise in the data signal. Thus, the two noise components can be used to cancel each other during demodulation of the data signal using the local oscillator.

Abstract: Attenuation caused by dispersion in an optical fiber communications system is compensated. A number of low-speed channels is to be transmitted across an optical fiber. Each low-speed channel is allocated a different frequency band for transmission. The attenuation caused by dispersion is estimated for each of the frequency bands. The power of each low-speed channel is adjusted to compensate for the estimated attenuation. The power-adjusted low-speed channels are frequency division multiplexed together to produce an electrical high-speed channel suitable for transmission across the communications system.

Abstract: Data is transmitted across an optical fiber communications system by splitting an incoming tributary into multiple low-speed data channels, modulating each of these into a stream of symbols (e.g., by using QAM modulation) and then frequency division multiplexing a number of symbol streams into a single high-speed channel to be transmitted across a fiber. The receiver reverses this process. In order to preserve the jitter tolerance for the overal system, reference clocks are used to remove unwanted jitter in the timing of the system.

Abstract: A transmitter subsystem generates an optical signal which contains multiple subbands of information. The subbands have different polarization. For example, in one approach, two or more optical transmitters generate optical signals which have different polarization. An optical combiner optically combines the optical signals into a composite optical signal for transmission across an optical fiber. In another aspect, each optical transmitter generates an optical signal containing both a lower optical sideband and an upper optical sideband (i.e., a double sideband optical signal). An optical filter selects the upper optical sideband of one optical signal and the lower optical sideband of another optical signal to produce a composite optical signal.

Abstract: A receiver for determining the location of a marker that is excited with an exciting waveform. A sensing array having coils is used to sense magnetic flux from the resonating marker. The coils provide inputs to the receiver. The receiver includes a correlation processor for analyzing the inputs in a coherent manner. Further, the exciting waveform is repeated with random dithering in order to eliminate system noise.

Abstract: A receiver for determining the location of a marker that is excited with an exciting waveform. A sensing array having coils is used to sense magnetic flux from the resonating marker. The coils provide inputs to the receiver. The receiver includes a correlation processor for analyzing the inputs in a coherent manner. The receiver determines the phase component of each of the inputs and compensates for differences.

Abstract: Embodiments of the invention are directed to an apparatus for use in a system that senses an excitable wireless target capable of being implanted in a body or tissue. The apparatus includes multiple electromagnetic field sensors arranged approximately in a common plane, and multiple sense signal output paths coupled to the sensors. Each one of the sensors and corresponding output paths is configured to provide an output signal representing at least a portion of an electromagnetic field provided by the marker, where the output signal is proportional to a component of the field at the sensor, where that component is substantially perpendicular to the plane. Various other configurations regarding this apparatus, as well as the overall system and methods of exciting and receiving signals from wireless markers, are also disclosed.

Abstract: A frequency division multiplexing (FDM) node used in optical communications networks provides add-drop multiplexing (ADM) functionality between optical high-speed channels and electrical low-speed channels. The FDM node includes a high-speed system and an ADM crosspoint. The high-speed system converts between an optical high-speed channel and its constituent electrical low-speed channels through the use of frequency division multiplexing and preferably also QAM modulation. The ADM crosspoint couples incoming low-speed channels to outgoing low-speed channels, thus implementing the ADM functionality for the FDM node.

Abstract: A frequency division multiplexing (FDM) node used in optical communications networks provides add-drop multiplexing (ADM) functionality between optical high-speed channels and electrical low-speed channels. The FDM node includes a high-speed system and an ADM crosspoint. The high-speed system converts between an optical high-speed channel and its constituent electrical low-speed channels through the use of frequency division multiplexing and preferably also QAM modulation. The ADM crosspoint couples incoming low-speed channels to outgoing low-speed channels, thus implementing the ADM functionality for the FDM node.