Abstract: The present invention provides a biocompatible and hydrophilic polymer conjugate comprising a linear, aliphatic copolymer backbone to which is conjugated a binding moiety and an agent. The binding moiety is conjugated to an end of the copolymer backbone and facilitates targeted delivery of the agent. Also provided are methods for preparing such polymer conjugates via free radical polymerisation techniques such as reversible addition fragmentation chain transfer (RAFT) polymerisation and uses of such polymer conjugates in diagnosis or therapy.

Abstract: The present invention relates to a method of adversely affecting a biofilm, the method comprising exposing the biofilm to a composition comprising an effective amount of polymer that incorporates within its backbone structure a first polymerised residue of ethylenically unsaturated monomer, said first polymerised monomer residue comprising a covalently bound moiety that (i) presents pendant from the backbone structure, and (ii) comprises a cationic functional group or precursor functional group thereof.

Abstract: The present invention relates to a method of adversely affecting a biofilm, the method comprising exposing the biofilm to a composition comprising an effective amount of polymer that incorporates within its backbone structure a first polymerised residue of ethylenically unsaturated monomer, said first polymerised monomer residue comprising a covalently bound moiety that (i) presents pendant from the backbone structure, and (ii) comprises a cationic functional group or precursor functional group thereof.

Abstract: A process for modifying a polymeric surface, the process comprising; contacting the polymeric surface with a solution comprising at least one ethylenically unsaturated monomer; and exposing the polymeric surface in contact with the solution to ultra-violet light to provide a graft-polymer of the monomer coated on the polymeric surface.

Abstract: The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerization initiators and a plurality of surface binding groups. Pendant polymers may be grafted from at least some of the polymerization initiators.

Abstract: The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerisation initiators and a plurality of surface binding groups. Pendant polymers may be grafted from at least some of the polymerisation initiators.

Abstract: The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerization initiators and a plurality of surface binding groups; and pendant polymers grafted from at least some of the polymerization initiators.

Abstract: The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerisation initiators and a plurality of surface binding groups; and pendant polymers grafted from at least some of the polymerisation initiators.