Patents by Inventor Laurence R. McCarthy

Laurence R. McCarthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9127309
    Abstract: Described are approaches for the identification, detection, and quantification of nucleic acids in a biological sample. These methods are based, in part, on the elucidation of anomalous migration properties of short nucleic acid molecules when conjugated to a fluorescent label, such as fluorescein labels, such that a smaller nucleic acid reliably migrates slower than a larger nucleic acid under the same conditions of separation.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: September 8, 2015
    Assignee: Qiagen Mansfield, Inc.
    Inventors: Ming-Chou Lee, Sergey V. Voronov, Laurence R. McCarthy, Lilly I. Kong, Vesselin Tenkov Diankov
  • Publication number: 20140178872
    Abstract: Described are approaches for the identification, detection, and quantification of nucleic acids in a biological sample. These methods are based, in part, on the elucidation of anomalous migration properties of short nucleic acid molecules when conjugated to a fluorescent label, such as fluorescein labels, such that a smaller nucleic acid reliably migrates slower than a larger nucleic acid under the same conditions of separation.
    Type: Application
    Filed: January 31, 2012
    Publication date: June 26, 2014
    Applicant: PRIMERADX, INC.
    Inventors: Ming-Chou Lee, Sergey V. Voronov, Laurence R. McCarthy, Lilly I. Kong, Vesselin Tenkov Diankov
  • Patent number: 5155019
    Abstract: A method and apparatus for detecting the presence of biological activity in a sample of material. In the method, a sample of the material is placed in a closed container with a growth medium which includes a carbon source which may be metabolized to produce carbon dioxide. The medium with the sample therein is exposed to conditions conducive to the occurrence of normal metabolic process for a period of time sufficient to cause production of CO.sub.2 by the metabolism of the carbon source. Thereafter, the presence of CO.sub.2 in the gaseous atmosphere above the medium is detected by measuring the infrared absorbance of the gaseous atmosphere with the container by passing an infrared beam through the container and the gaseous atmosphere and detecting the infrared absorbance of the gaseous atmosphere.
    Type: Grant
    Filed: July 28, 1988
    Date of Patent: October 13, 1992
    Assignee: Becton, Dickinson and Company
    Inventors: Mark L. Sussman, Joseph E. Ahnell, Laurence R. McCarthy
  • Patent number: 4659658
    Abstract: A method for identification of a microorganism includes combining in a suitable fluid the microorganism and a latex containing a particle coated with about 1 to 150 .mu.g per ml of latex of a lectin specific for the microorganism. Binding of the microorganism and lectin causes agglutination which is detected. The microorganism is identified by the agglutination as that organism which is specific for the lectin. The invention includes a reagent which may be included with other materials in a kit of materials useful for performing the method of the invention.
    Type: Grant
    Filed: December 26, 1984
    Date of Patent: April 21, 1987
    Assignee: Becton, Dickinson and Company
    Inventors: Laurence R. McCarthy, H. Mark Perks