Abstract: An inhaler for delivery of medicament from a canister which is compressible to deliver a dose of medicament. The inhaler comprises a housing (1) for holding a canister (2), the housing having a mouthpiece (5) for inhalation of a dose of medicament delivered by the canister (2) and a breath-actuated actuation mechanism (6) for compressing a canister (2) held in the housing (1) in response to inhalation at the mouthpiece (5). The actuation mechanism (6) includes a vane in the form of a flap (13) disposed across a duct (24, 32) extending from the mouth piece (5) arranged to lock the canister (2) in a compressed state and being responsive to the inhalation at the mouthpiece (5) to release the canister (2) when the level of inhalation at the mouthpiece falls below a predetermined threshold.

Abstract: An inhaler for delivery of medicament from a canister which is compressible to deliver a dose of medicament. The inhaler comprises a housing (1) for holding a canister (2), the housing having a mouthpiece (5) for inhalation of a dose of medicament delivered by the canister (2) and a breath-actuated actuation mechanism (6) for compressing a canister (2) held in the housing (1) in response to inhalation at the mouthpiece (5). The actuation mechanism (6) includes a vane in the form of a flap (13) disposed across a duct (24, 32) extending from the mouth piece (5) arranged to lock the canister (2) in a compressed state and being responsive to the inhalation at the mouthpiece (5) to release the canister (2) when the level of inhalation at the mouthpiece falls below a predetermined threshold.

Abstract: A combined filter and HME has a rectangular housing with an inlet port and an outlet port. A pleated filter element is located in the housing towards the outlet port and an HME element is located towards the inlet port. An oval deflector between the HME element and the inlet port is oriented with its longer axis aligned with the shorter lateral dimension of the housing, so that gas from the inlet is deflected preferentially along the longer lateral dimension of the housing, thereby giving a more evenly distributed gas flow over the surface of the HME element.